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With the flourishing of social media platforms, vision-language pre-training (VLP) recently has received great attention and many remarkable progresses have been achieved. The success of VLP largely benefits from the information…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Zhiyuan Ma , Jianjun Li , Guohui Li , Kaiyan Huang

Aligning signals from different modalities is an important step in vision-language representation learning as it affects the performance of later stages such as cross-modality fusion. Since image and text typically reside in different…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Jiali Duan , Liqun Chen , Son Tran , Jinyu Yang , Yi Xu , Belinda Zeng , Trishul Chilimbi

In clinical practice, many diagnosis tasks rely on the identification of cells in histopathology images. While supervised machine learning techniques require labels, providing manual cell annotations is time-consuming due to the large…

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

Medical image understanding plays a crucial role in enabling automated diagnosis and data-driven clinical decision support. However, its progress is impeded by two primary challenges: the limited availability of high-quality annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tianchen Fang , Guiru Liu

Content-based medical image retrieval is an important diagnostic tool that improves the explainability of computer-aided diagnosis systems and provides decision making support to healthcare professionals. Medical imaging data, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Yunyan Xing , Benjamin J. Meyer , Mehrtash Harandi , Tom Drummond , Zongyuan Ge

Scribble annotations significantly reduce the cost and labor required for dense labeling in large medical datasets with complex anatomical structures. However, current scribble-supervised learning methods are limited in their ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Luyi Qiu , Tristan Till , Xiaobao Guo , Adams Wai-Kin Kong

Medical anomaly detection (MAD) and segmentation play a critical role in assisting clinical diagnosis by identifying abnormal regions in medical images and localizing pathological regions. Recent CLIP-based studies are promising for anomaly…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Thuy Truong Tran , Minh Kha Do , Phuc Nguyen Duy , Min Hun Lee

Visual grounding (VG) is the capability to identify the specific regions in an image associated with a particular text description. In medical imaging, VG enhances interpretability by highlighting relevant pathological features…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Ta Duc Huy , Duy Anh Huynh , Yutong Xie , Yuankai Qi , Qi Chen , Phi Le Nguyen , Sen Kim Tran , Son Lam Phung , Anton van den Hengel , Zhibin Liao , Minh-Son To , Johan W. Verjans , Vu Minh Hieu Phan

Medical language-guided segmentation, integrating textual clinical reports as auxiliary guidance to enhance image segmentation, has demonstrated significant improvements over unimodal approaches. However, its inherent reliance on paired…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Shuchang Ye , Usman Naseem , Mingyuan Meng , Jinman Kim

As artificial intelligence (AI) becomes increasingly central to healthcare, the demand for explainable and trustworthy models is paramount. Current report generation systems for chest X-rays (CXR) often lack mechanisms for validating…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier

While current research has shown the importance of Multi-parametric MRI (mpMRI) in diagnosing prostate cancer (PCa), further investigation is needed for how to incorporate the specific structures of the mpMRI data, such as the regional…

Machine Learning · Statistics 2021-11-04 Jin Jin , Lin Zhang , Ethan Leng , Gregory J. Metzger , Joseph S. Koopmeiners

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Vision-Language Models (VLMs) such as CLIP learn a shared embedding space for images and text, yet their representations remain geometrically separated, a phenomenon known as the modality gap. This gap limits tasks requiring cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Hongyuan Liu , Qinli Yang , Wen Li , Zhong Zhang , Jiaming Liu , Wei Han , Zhili Qin , Jinxia Guo , Junming Shao

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

Recent advances in computational pathology have leveraged vision-language models to learn joint representations of Hematoxylin and Eosin (HE) images with spatial transcriptomic (ST) profiles. However, existing approaches typically align HE…

Learning medical visual representations directly from paired images and reports through multimodal self-supervised learning has emerged as a novel and efficient approach to digital diagnosis in recent years. However, existing models suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Juan Zhou , Xiaofei Zhu , Yongmei Li , Yudong Zhang , Xin Luo

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Accurate analysis of pathological images is essential for automated tumor diagnosis but remains challenging due to high structural similarity and subtle morphological variations in tissue images. Current vision-language (VL) models often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yating Huang , Ziyan Huang , Lintao Xiang , Qijun Yang , Hujun Yin