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In recent years, diffusion models have gained popularity for their ability to generate higher-quality images in comparison to GAN models. However, like any other large generative models, these models require a huge amount of data,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Rajesh Shrestha , Bowen Xie

In this paper we consider the problem of acoustic inversion in the context of the optoacoustic tomography image reconstruction problem. By leveraging the ability of the recently proposed diffusion models for image generative tasks among…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 M. G. González , M. Vera , A. Dreszman , L. J. Rey Vega

Machine learning is a powerful approach for fitting microstructural models to diffusion MRI data. Early machine learning microstructure imaging implementations trained regressors to estimate model parameters in a supervised way, using…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Jason P. Lim , Stefano B. Blumberg , Neil Narayan , Sean C. Epstein , Daniel C. Alexander , Marco Palombo , Paddy J. Slator

Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…

Weakly-supervised diffusion models (DMs) in anomaly segmentation, leveraging image-level labels, have attracted significant attention for their superior performance compared to unsupervised methods. It eliminates the need for pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Yiming Che , Fazle Rafsani , Jay Shah , Md Mahfuzur Rahman Siddiquee , Teresa Wu

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Anomaly detection in computational pathology aims to identify rare and scarce anomalies where disease-related data are often limited or missing. Existing anomaly detection methods, primarily designed for industrial settings, face…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Jinsol Song , Jiamu Wang , Anh Tien Nguyen , Keunho Byeon , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Recent progress in image generation has sparked research into controlling these models through condition signals, with various methods addressing specific challenges in conditional generation. Instead of proposing another specialized…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Xirui Li , Charles Herrmann , Kelvin C. K. Chan , Yinxiao Li , Deqing Sun , Chao Ma , Ming-Hsuan Yang

Time series anomaly detection (TSAD) has been an important area of research for decades, with reconstruction-based methods, mostly based on generative models, gaining popularity and demonstrating success. Diffusion models have recently…

Machine Learning · Computer Science 2026-03-02 Kohei Obata , Zheng Chen , Yasuko Matsubara , Lingwei Zhu , Yasushi Sakurai

Diffusion models have advanced unsupervised anomaly detection by improving the transformation of pathological images into pseudo-healthy equivalents. Nonetheless, standard approaches may compromise critical information during pathology…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Cosmin I. Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Anomaly detection is the process of identifying atypical data samples that significantly deviate from the majority of the dataset. In the realm of clinical screening and diagnosis, detecting abnormalities in medical images holds great…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xianyao Hu , Congming Jin

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Diffusion models have recently been shown to excel in many image reconstruction tasks that involve inverse problems based on a forward measurement operator. A common framework uses task-agnostic unconditional models that are later…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Alper Güngör , Bahri Batuhan Bilecen , Tolga Çukur

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Unsupervised pathology detection can be implemented by training a model on healthy data only and measuring the deviation from the training set upon inference, for example with CNN-based feature extraction and one-class classifiers, or…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Aissam Djahnine , Alexandre Popoff , Emilien Jupin-Delevaux , Vincent Cottin , Olivier Nempont , Loic Boussel

Motion artifacts remain a significant challenge in Magnetic Resonance Imaging (MRI), compromising diagnostic quality and potentially leading to misdiagnosis or repeated scans. Existing deep learning approaches for motion artifact correction…

Image and Video Processing · Electrical Eng. & Systems 2025-11-24 Paolo Angella , Luca Balbi , Fabrizio Ferrando , Paolo Traverso , Rosario Varriale , Vito Paolo Pastore , Matteo Santacesaria

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström