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Due to the diversity of brain anatomy and the scarcity of annotated data, supervised anomaly detection for brain MRI remains challenging, driving the development of unsupervised anomaly detection (UAD) approaches. Current UAD methods…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Li , Zhenfeng Zhuang , Jingyu Lin , Yu Liu , Yifei Chen , Qiong Peng , Lequan Yu , Liansheng Wang

Normative modeling has emerged as a pivotal approach for characterizing heterogeneity and individual variance in neurodegenerative diseases, notably Alzheimer's disease(AD). One of the challenges of cortical normative modeling is the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-13 Jianwei Zhang , Yonggang Shi

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

Known for their impressive performance in generative modeling, diffusion models are attractive candidates for density-based anomaly detection. This paper investigates different variations of diffusion modeling for unsupervised and…

Machine Learning · Computer Science 2026-05-11 Victor Livernoche , Vineet Jain , Yashar Hezaveh , Siamak Ravanbakhsh

Purpose/Objective: Brain tumors result in 20 years of lost life on average. Standard therapies induce complex structural changes in the brain that are monitored through MRI. Recent developments in artificial intelligence (AI) enable…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Selena Huisman , Nordin Belkacemi , Vera Keil , Joost Verhoeff , Szabolcs David

Most deep anomaly detection models are based on learning normality from datasets due to the difficulty of defining abnormality by its diverse and inconsistent nature. Therefore, it has been a common practice to learn normality under the…

Machine Learning · Computer Science 2023-09-19 Minkyung Kim , Jongmin Yu , Junsik Kim , Tae-Hyun Oh , Jun Kyun Choi

In the context of flexible manufacturing systems that are required to produce different types and quantities of products with minimal reconfiguration, this paper addresses the problem of unsupervised multi-class anomaly detection: develop a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Haonan Yin , Guanlong Jiao , Qianhui Wu , Borje F. Karlsson , Biqing Huang , Chin Yew Lin

Collective insights from a group of experts have always proven to outperform an individual's best diagnostic for clinical tasks. For the task of medical image segmentation, existing research on AI-based alternatives focuses more on…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Aimon Rahman , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Diffusion models generate high-quality images through progressive denoising but are computationally intensive due to large model sizes and repeated sampling. Knowledge distillation, which transfers knowledge from a complex teacher to a…

Machine Learning · Computer Science 2025-04-04 Dohyun Kim , Sehwan Park , Geonhee Han , Seung Wook Kim , Paul Hongsuck Seo

Magnetic Resonance Fingerprinting (MRF) is a time-efficient approach to quantitative MRI, enabling the mapping of multiple tissue properties from a single, accelerated scan. However, achieving accurate reconstructions remains challenging,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Perla Mayo , Carolin M. Pirkl , Alin Achim , Bjoern H. Menze , Mohammad Golbabaee

Conditional image generation has paved the way for several breakthroughs in image editing, generating stock photos and 3-D object generation. This continues to be a significant area of interest with the rise of new state-of-the-art methods…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Vedant Singh , Surgan Jandial , Ayush Chopra , Siddharth Ramesh , Balaji Krishnamurthy , Vineeth N. Balasubramanian

In order to navigate safely and reliably in off-road and unstructured environments, robots must detect anomalies that are out-of-distribution (OOD) with respect to the training data. We present an analysis-by-synthesis approach for…

Detecting visual anomalies in diverse, multi-class real-world images is a significant challenge. We introduce \ours, a novel unsupervised multi-class visual anomaly detection framework. It integrates a Latent Diffusion Model (LDM) with a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Samet Hicsonmez , Abd El Rahman Shabayek , Djamila Aouada

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

Recently, a number of image-mixing-based augmentation techniques have been introduced to improve the generalization of deep neural networks. In these techniques, two or more randomly selected natural images are mixed together to generate an…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Khawar Islam , Muhammad Zaigham Zaheer , Arif Mahmood , Karthik Nandakumar

Unsupervised anomaly detection is a daunting task, as it relies solely on normality patterns from the training data to identify unseen anomalies during testing. Recent approaches have focused on leveraging domain-specific transformations or…

Machine Learning · Computer Science 2024-09-17 Hyuntae Kim , Changhee Lee

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Diffusion MRI (dMRI) is an important neuroimaging technique with high acquisition costs. Deep learning approaches have been used to enhance dMRI and predict diffusion biomarkers through undersampled dMRI. To generate more comprehensive raw…

Image and Video Processing · Electrical Eng. & Systems 2024-07-11 Juanhua Zhang , Ruodan Yan , Alessandro Perelli , Xi Chen , Chao Li

We present the first diffusion-based framework that can learn an unknown distribution using only highly-corrupted samples. This problem arises in scientific applications where access to uncorrupted samples is impossible or expensive to…

Machine Learning · Computer Science 2023-05-31 Giannis Daras , Kulin Shah , Yuval Dagan , Aravind Gollakota , Alexandros G. Dimakis , Adam Klivans
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