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Background: Antimicrobial resistance (AMR) is a major global public health problem, contributing to an estimated 4.95 million deaths in 2019 and projected to cause up to 10 million deaths annually and 100 trillion dollars in cumulative…

Populations and Evolution · Quantitative Biology 2026-01-06 Felipe Schardong , Claudio Jose Struchiner , Luiz Max Carvalho

Antimicrobial resistance is an emerging global health crisis that is undermining advances in modern medicine and, if unmitigated, threatens to kill 10 million people per year worldwide by 2050. Research over the last decade has demonstrated…

Quantitative Methods · Quantitative Biology 2020-09-24 K. Farquhar , H. Flohr , D. A. Charlebois

Swimming bacteria detect chemical gradients by performing temporal comparisons of recent measurements of chemical concentration. These comparisons are described quantitatively by the chemotactic response function, which we expect to…

Cell Behavior · Quantitative Biology 2009-11-13 Damon A. Clark , Lars C. Grant

Insects like dragonflies and cicadas possess nanoprotusions on their wings that rupture bacterial membranes upon contact, inspiring synthetic antibacterial surfaces mimicking this phenomenon. Designing such biomimetic surfaces requires…

Soft Condensed Matter · Physics 2025-01-22 Akash Singh , Yi Zhang , Qing Cao , Yumeng Li

Antibiotic resistance poses a significant threat in in-patient settings with high mortality. Using MIMIC-III data, we generated Sentence-BERT embeddings from clinical notes and applied Neural Networks and XGBoost to predict antibiotic…

Computation and Language · Computer Science 2025-09-19 Mahmoud Alwakeel , Michael E. Yarrington , Rebekah H. Wrenn , Ethan Fang , Jian Pei , Anand Chowdhury , An-Kwok Ian Wong

Analysis of microscopy images is one important tool in many fields of biomedical research, as it allows the quantification of a multitude of parameters at the cellular level. However, manual counting of these images is both tiring and…

Computer Vision and Pattern Recognition · Computer Science 2013-11-13 P. A Nogueira

Contrastive learning and self-supervised techniques have gained prevalence in computer vision for the past few years. It is essential for medical image analysis, which is often notorious for its lack of annotations. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Jun Li , Quan Quan , S. Kevin Zhou

Portable low-cost sensors and sensing systems for the identification and quantitative measurement of bacteria in field water are critical in preventing drinking water from being contaminated by bacteria. In this article, we reported the…

Quantitative Methods · Quantitative Biology 2013-12-03 Jing Jiang , Xinhao Wang , Ran Chao , Yukun Ren , Chengpeng Hu , Zhida Xu , Gang Logan Liu

Rapid and non-destructive assessment of milk quality is crucial to ensuring both nutritional value and food safety. In this study, we investigated the potential of visible and hyperspectral imaging as cost-effective and quick-response…

Centrifugation is a widespread laboratory technique used to separate mixtures into fractions characterized by a specific size, weight or density. We demonstrate that centrifugation can be also used to separate swimming cells having…

Soft Condensed Matter · Physics 2014-11-07 Claudio Maggi , Alessia Lepore , Jacopo Solari , Alessandro Rizzo , Roberto Di Leonardo

Fast and efficient calculations of optical responses using electromagnetic models require computational acceleration and compression techniques. A hierarchical matrix approach is adopted for this purpose. In order to model large-scale…

Non-invasive light scattering methods provide data on biological macromolecules (i.e. proteins, nucleic acids, as well as assemblies and larger entities composed of them) that are complementary with those of size exclusion chromatography,…

Biomolecules · Quantitative Biology 2018-10-02 Bernard Lorber

The technological progress in spatial-light modulators (SLM) technology has made it possible to use those devices as programmable active focal-plane phase coronagraphic masks, opening the door to novel versatile and adaptive high-contrast…

Instrumentation and Methods for Astrophysics · Physics 2022-11-09 J. G. Kuhn , P. Patapis

We propose a general parametrizable model to capture the dynamic interaction among bacteria in the formation of micro-colonies. micro-colonies represent the first social step towards the formation of structured multicellular communities…

Populations and Evolution · Quantitative Biology 2014-10-30 Luca Canzian , Kun Zhao , Gerard C. L. Wong , Mihaela van der Schaar

Optical microscopy contributes to the ever-increasing progress in biological and biomedical studies, as it allows the implementation of minimally invasive experimental pipelines to translate the data of measured samples into valuable…

Quantitative Methods · Quantitative Biology 2025-04-03 Elena Corbetta , Thomas Bocklitz

Identification of antimicrobial peptides is an important and necessary issue in today's era. Antimicrobial peptides are essential as an alternative to antibiotics for biomedical applications and many other practical applications. These…

Machine Learning · Computer Science 2025-12-17 Reyhaneh Keshavarzpour , Eghbal Mansoori

The skin microbiome plays an important role in the maintenance of a healthy skin. It is an ecosystem, composed of several species, competing for resources and interacting with the skin cells. Imbalance in the cutaneous microbiome, also…

Quantitative Methods · Quantitative Biology 2022-06-22 Eléa Thibault Greugny , Georgios N Stamatas , François Fages

Biological interactions with material surfaces span a wide range of length scales, yet conventional surface measurements often fail to account for scale, limiting the insights they provide for surface engineering. Here, we investigate how…

Development of the new antimicrobial agents against antibiotic resistance pathogens is the nowadays challenge. Antimicrobial peptides (AMP) occur as important defence agents in many organisms and offer a viable alternative to conventional…

Biomolecules · Quantitative Biology 2013-07-24 M. Pirtskhalava , B. Vishnepolsky , M. Grigolava

Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance…

Applications · Statistics 2018-01-31 Rajita Menon , Vivek Ramanan , Kirill S. Korolev