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Evaluating large language models (LLMs) in the biomedical domain requires benchmarks that can distinguish reasoning from pattern matching and remain discriminative as model capabilities improve. Existing biomedical question answering (QA)…

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare,…

Artificial Intelligence · Computer Science 2025-02-27 Guoxin Wang , Minyu Gao , Shuai Yang , Ya Zhang , Lizhi He , Liang Huang , Hanlin Xiao , Yexuan Zhang , Wanyue Li , Lu Chen , Jintao Fei , Xin Li

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…

Artificial Intelligence · Computer Science 2025-08-27 Armin Berger , Sarthak Khanna , David Berghaus , Rafet Sifa

Medical dialogue systems (MDSs) aim to assist doctors and patients with a range of professional medical services, i.e., diagnosis, treatment and consultation. The development of MDSs is hindered because of a lack of resources. In…

Computation and Language · Computer Science 2022-03-02 Guojun Yan , Jiahuan Pei , Pengjie Ren , Zhaochun Ren , Xin Xin , Huasheng Liang , Maarten de Rijke , Zhumin Chen

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

Recent advances in fine-tuning large language models (LLMs) with reinforcement learning (RL) have shown promising improvements in complex reasoning tasks, particularly when paired with chain-of-thought (CoT) prompting. However, these…

Machine Learning · Computer Science 2025-04-04 Hung Le , Dai Do , Dung Nguyen , Svetha Venkatesh

Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective…

Computation and Language · Computer Science 2026-02-02 Congying Liu , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Large Language Models (LLMs) offer powerful capabilities in code generation, natural language understanding, and domain-specific reasoning. Their application to quantum software development remains limited, in part because of the lack of…

Software Engineering · Computer Science 2026-04-20 Abdul Basit , Nouhaila Innan , Muhammad Haider Asif , Minghao Shao , Muhammad Kashif , Alberto Marchisio , Muhammad Shafique

Large language models (LLMs) make remarkable progress in reasoning tasks. Among different reasoning modes, inductive reasoning, due to its better alignment with human learning, attracts increasing interest. However, research on inductive…

Computation and Language · Computer Science 2025-10-17 Kedi Chen , Zhikai Lei , Xu Guo , Xuecheng Wu , Siyuan Zeng , Jianghao Yin , Yinqi Zhang , Qin Chen , Jie Zhou , Liang He , Qipeng Guo , Kai Chen , Wei Zhang

Recently, large language model (LLM) based artificial intelligence (AI) systems have demonstrated remarkable capabilities in natural language understanding and generation. However, these models face a significant challenge when it comes to…

This work introduces MediQAl, a French medical question answering dataset designed to evaluate the capabilities of language models in factual medical recall and reasoning over real-world clinical scenarios. MediQAl contains 32,603 questions…

Computation and Language · Computer Science 2026-05-19 Adrien Bazoge

Large Reasoning Models (LRMs) have introduced a new paradigm in AI by enabling models to ``think before responding" via chain-of-thought reasoning. However, the absence of open and reproducible recipes for building reasoning-centric medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Xiaoke Huang , Juncheng Wu , Hui Liu , Xianfeng Tang , Yuyin Zhou

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

Logical reasoning consistently plays a fundamental and significant role in the domains of knowledge engineering and artificial intelligence. Recently, Large Language Models (LLMs) have emerged as a noteworthy innovation in natural language…

Computation and Language · Computer Science 2024-09-17 Fangzhi Xu , Qika Lin , Jiawei Han , Tianzhe Zhao , Jun Liu , Erik Cambria

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Answering complex real-world questions in the medical domain often requires accurate retrieval from medical Textual Knowledge Graphs (medical TKGs), as the relational path information from TKGs could enhance the inference ability of Large…

Computation and Language · Computer Science 2026-04-14 Jiatan Huang , Mingchen Li , Zonghai Yao , Dawei Li , Yuxin Zhang , Zhichao Yang , Yongkang Xiao , Feiyun Ouyang , Xiaohan Li , Shuo Han , Hong Yu

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable…

Computation and Language · Computer Science 2025-05-30 Yakun Zhu , Zhongzhen Huang , Linjie Mu , Yutong Huang , Wei Nie , Jiaji Liu , Shaoting Zhang , Pengfei Liu , Xiaofan Zhang

Multimodal large language models (MLLMs) have shown promising reasoning abilities, yet evaluating their performance in specialized domains remains challenging. STEM reasoning is a particularly valuable testbed because it provides highly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Jing Jin , Hao Liu , Yan Bai , Yihang Lou , Zhenke Wang , Tianrun Yuan , Juntong Chen , Yongkang Zhu , Fanhu Zeng , Xuanyu Zhu , Tao Feng , Yige Xu

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Large language models (LLMs) have obtained promising results in mathematical reasoning, which is a foundational skill for human intelligence. Most previous studies focus on improving and measuring the performance of LLMs based on textual…

Computation and Language · Computer Science 2024-11-04 Wentao Liu , Qianjun Pan , Yi Zhang , Zhuo Liu , Ji Wu , Jie Zhou , Aimin Zhou , Qin Chen , Bo Jiang , Liang He