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Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

Large vision-language models (LVMs) hold a great promise for automating medical report generation, potentially reducing the burden of manual reporting. State-of-the-art (SOTA) research fine-tunes general LVMs with medical data to align…

Computation and Language · Computer Science 2025-04-07 Hao Wang , Shuchang Ye , Jinghao Lin , Usman Naseem , Jinman Kim

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is…

Computation and Language · Computer Science 2026-04-28 Yurui Xiang , Xingyi Mao , Rui Sheng , Zixin Chen , Zelin Zang , Yuyang Wu , Haipeng Zeng , Huamin Qu , Yushi Sun , Yanna Lin

Large Language Models (LLMs) have demonstrated potential in predicting mental health outcomes from online text, yet traditional classification methods often lack interpretability and robustness. This study evaluates structured reasoning…

Computation and Language · Computer Science 2026-01-09 Avinash Patil , Amardeep Kour Gedhu

Large Reasoning Models (LRMs) with long chain-of-thought reasoning have recently achieved remarkable success. Yet, equipping domain-specialized models with such reasoning capabilities, referred to as "Reasoning + X", remains a significant…

Computation and Language · Computer Science 2026-01-12 Junyao Yang , Chen Qian , Dongrui Liu , Wen Shen , Yong Liu , Jing Shao

Large Language Models (LLMs) show promise in medicine but are prone to factual and logical errors, which is unacceptable in this high-stakes field. To address this, we introduce the "Haibu Mathematical-Medical Intelligent Agent" (MMIA), an…

Artificial Intelligence · Computer Science 2025-10-10 Yilun Zhang , Dexing Kong

Large language models with reasoning capabilities have demonstrated impressive performance across a wide range of domains. In clinical applications, a transparent, step-by-step reasoning process provides physicians with strong evidence to…

Artificial Intelligence · Computer Science 2025-12-16 Linjie Mu , Yannian Gu , Zhongzhen Huang , Yakun Zhu , Shaoting Zhang , Xiaofan Zhang

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

Computation and Language · Computer Science 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Large language models (LLMs) have saturated standard medical benchmarks that test factual recall, yet their ability to perform higher-order reasoning, such as synthesizing evidence from multiple sources, remains critically under-explored.…

Computation and Language · Computer Science 2026-05-12 Huy Hoang Ha , Benoit Favre , Francois Portet

Large language models (LLMs) are increasingly deployed in settings where reasoning, such as multi-step problem solving and chain-of-thought, is essential. Yet, current evaluation practices overwhelmingly report single-run accuracy while…

Artificial Intelligence · Computer Science 2025-12-09 Nearchos Potamitis , Lars Klein , Akhil Arora

Despite recent progress in text-prompt-based medical image segmentation, these methods are limited to single-round dialogues and fail to support multi-round reasoning, which is important for medical education scenarios. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Qinyue Tong , Ziqian Lu , Jun Liu , Rui Zuo , Zheming Lu , Yueming Jin

Understanding human instructions to identify the target objects is vital for perception systems. In recent years, the advancements of Large Language Models (LLMs) have introduced new possibilities for image segmentation. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Junchi Wang , Lei Ke

While large language models (LLMs) have demonstrated exceptional performance in recent natural language processing (NLP) tasks, their deployment poses substantial challenges due to high computational and memory demands in real-world…

Computation and Language · Computer Science 2024-02-27 Chenglin Li , Qianglong Chen , Liangyue Li , Caiyu Wang , Yicheng Li , Zulong Chen , Yin Zhang

Large Language Models (LLMs) are predominantly assessed based on their common sense reasoning, language comprehension, and logical reasoning abilities. While models trained in specialized domains like mathematics or coding have demonstrated…

Software Engineering · Computer Science 2026-01-08 Danny Brahman , Mohammad Mahoor

In current Large Language Models we can trust the production of smoothly flowing prose on the basis of the principles of machine learning. However, there is no comparably principled basis to justify trust in the content of the text…

Artificial Intelligence · Computer Science 2026-05-15 Leslie G. Valiant

Biomedical researchers increasingly rely on large-scale structured databases for complex analytical tasks. However, current text-to-SQL systems often struggle to map qualitative scientific questions into executable SQL, particularly when…

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang