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Instruction-guided image editing has seen remarkable progress with models like FLUX.2 and Qwen-Image-Edit, yet they still struggle with complex scenarios with multiple similar instances each requiring individual edits. We observe that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Ziqian Liu , Stephan Alaniz

Multimodal large language models (MLLMs) have recently demonstrated remarkable reasoning abilities with reinforcement learning paradigm. Although several multimodal reasoning models have been explored in the medical domain, most of them…

Artificial Intelligence · Computer Science 2025-09-11 Ruiqi Wu , Yuang Yao , Tengfei Ma , Chenran Zhang , Na Su , Tao Zhou , Geng Chen , Wen Fan , Yi Zhou

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

Multimodal AI systems have achieved remarkable performance across a broad range of real-world tasks, yet the mechanisms underlying visual-language reasoning remain surprisingly poorly understood. We report three findings that challenge…

Artificial Intelligence · Computer Science 2026-04-03 Mohammad Asadi , Jack W. O'Sullivan , Fang Cao , Tahoura Nedaee , Kamyar Rajabalifardi , Fei-Fei Li , Ehsan Adeli , Euan Ashley

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

Image and Video Processing · Electrical Eng. & Systems 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

Surgical procedures unfold in complex environments demanding coordination between surgical teams, tools, imaging and increasingly, intelligent robotic systems. Ensuring safety and efficiency in ORs of the future requires intelligent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Ege Özsoy , Chantal Pellegrini , David Bani-Harouni , Kun Yuan , Matthias Keicher , Nassir Navab

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM…

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Xiang He , Weiye Song , Yiming Wang , Fabio Poiesi , Ji Yi , Manishi Desai , Quanqing Xu , Kongzheng Yang , Yi Wan

Artificial Intelligence (AI) is necessary to address the large and growing deficit in retina and healthcare access globally. And mobile AI diagnostic platforms running in the Cloud may effectively and efficiently distribute such AI…

Retinal template matching and registration is an important challenge in teleophthalmology with low-cost imaging devices. However, the images from such devices generally have a small field of view (FOV) and image quality degradations, making…

Image and Video Processing · Electrical Eng. & Systems 2018-11-30 Chen Gong , N. Benjamin Erichson , John P. Kelly , Laura Trutoiu , Brian T. Schowengerdt , Steven L. Brunton , Eric J. Seibel

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Appreciating multi-figure paintings requires understanding how characters relate through subtle cues like gaze alignment, gesture, and spatial arrangement. We present MIRAGE, an evidence-centric framework designed to scaffold the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jui-Cheng Chiu , Yu-Chao Wang , Shengyang Luo , Tongyan Wang , Qi Yang , Nabin Khanal , Yingjie Victor Chen

Large Multimodal Models (LMMs) have made significant strides in visual question-answering for single images. Recent advancements like long-context LMMs have allowed them to ingest larger, or even multiple, images. However, the ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Tsung-Han Wu , Giscard Biamby , Jerome Quenum , Ritwik Gupta , Joseph E. Gonzalez , Trevor Darrell , David M. Chan

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

Large Multimodal Models (LMMs) have achieved remarkable progress in generating photorealistic and prompt-aligned images, but they often produce outputs that contradict verifiable knowledge, especially when prompts involve fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yang Tian , Fan Liu , Jingyuan Zhang , Wei Bi , Yupeng Hu , Liqiang Nie

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…