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Ising machines, including quantum annealing machines, are promising next-generation computers for combinatorial optimization problems. However, due to hardware limitations, most Ising-type hardware can only solve objective functions…

Statistical Mechanics · Physics 2025-10-29 Kazuki Ikeuchi , Yoshiki Matsuda , Shu Tanaka

This paper develops an algorithmic solution using Ising machines to solve large-scale higher-order binary optimization (HOBO) problems with inequality constraints for resource optimization in wireless communications systems. Quadratic…

Information Theory · Computer Science 2025-09-25 Gan Zheng , Ioannis Krikidis

Collaborative filtering models generally perform better than content-based filtering models and do not require careful feature engineering. However, in the cold-start scenario collaborative information may be scarce or even unavailable,…

Information Retrieval · Computer Science 2022-05-13 Artyom Nikitin , Andrei Chertkov , Rafael Ballester-Ripoll , Ivan Oseledets , Evgeny Frolov

We propose a fault-tolerant quantum computer architecture for trapped-ion devices, which we call the walking cat architecture. Our blueprint includes a compiler, a detailed description of all the quantum error-correction protocols, a…

The field of quantum computing has grown from concept to demonstration devices over the past 20 years. Universal quantum computing offers efficiency in approaching problems of scientific and commercial interest, such as factoring large…

We propose a new kernel that quantifies success for the task of computing a core-periphery partition for an undirected network. Finding the associated optimal partitioning may be expressed in the form of a quadratic unconstrained binary…

Social and Information Networks · Computer Science 2022-01-06 Catherine F. Higham , Desmond J. Higham , Francesco Tudisco

For decades, researchers have been applying computer simulation to address problems in biology. However, many of these "grand challenges" in computational biology, such as simulating how proteins fold, remained unsolved due to their great…

Biological Physics · Physics 2009-01-08 Stefan M. Larson , Christopher D. Snow , Michael Shirts , Vijay S. Pande

Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size as…

Quantum Physics · Physics 2017-04-27 Simon E. Nigg , Niels Loerch , Rakesh P. Tiwari

Quantum annealing is a promising approach for solving combinatorial optimization problems. However, its performance is often limited by the overhead of additional qubits required for embedding logical QUBO models onto quantum annealers.…

Quantum Physics · Physics 2026-01-27 Kohei Suda , Soshun Naito , Yoshihiko Hasegawa

Achieving chemical accuracy for strongly correlated molecules is a defining milestone for first-generation, fault-tolerant quantum computers, yet the factorial growth of three, four, and six-index tensor contractions in coupled-cluster…

We present a heuristic algorithm designed to solve Quadratic Unconstrained Binary Optimization (QUBO) problems efficiently. The algorithm, referred to as IC-D2S, leverages a hybrid approach using Ising and classical machines to address very…

Hardware Architecture · Computer Science 2025-02-20 Armin Abdollahi , Mehdi Kamal , Massoud Pedram

Solving optimization tasks using variational quantum algorithms has emerged as a crucial application of the current noisy intermediate-scale quantum devices. However, these algorithms face several difficulties like finding suitable ansatz…

Quantum Physics · Physics 2022-06-22 Pranav Chandarana , Pablo S. Vieites , Narendra N. Hegade , Enrique Solano , Yue Ban , Xi Chen

Molecular docking is a crucial phase in drug discovery, involving the precise determination of the optimal spatial arrangement between two molecules when they bind. The such analysis, the 3D structure of molecules is a fundamental…

Quantum Physics · Physics 2024-03-04 Arit Kumar Bishwas , Arish Pitchai , Anuraj Som

When tackling binary optimization problems using quantum algorithms, the conventional Ising representation and Quantum Approximate Optimization Algorithm (QAOA) encounter difficulties in efficiently handling errors for large-scale problems…

Quantum Physics · Physics 2023-05-16 Ke Wan , Yiwen Liu

Quantum computing has emerged as a promising alternative for solving combinatorial optimization problems. The standard approach for encoding optimization problems on quantum processing units (QPUs) involves transforming them into their…

Emerging Technologies · Computer Science 2025-10-15 Meerzhan Kanatbekova , Vincenzo De Maio , Ivona Brandic

Quantum computing holds great potential to accelerate the process of solving complex combinatorial optimization problems. The Distributed Quantum Approximate Optimization Algorithm (DQAOA) addresses high-dimensional, dense problems using…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Zhihao Xu , Srikar Chundury , Seongmin Kim , Amir Shehata , Xinyi Li , Ang Li , Tengfei Luo , Frank Mueller , In-Saeng Suh

In the field of quantum computing, combinatorial optimization problems are typically addressed using QUBO (Quadratic Unconstrained Binary Optimization) solvers. However, these solvers are often insufficient for tackling higher-order…

Quantum Physics · Physics 2024-07-24 Yuichiro Minato

Combinatorial optimization is considered a promising class of problems in which quantum computers can show significant advantages. However, problems of practical relevance typically have more variables than current or foreseeable quantum…

Quantum Physics · Physics 2025-12-23 Mathias Schmid , Naeimeh Mohseni , Michael J. Hartmann

The availability of a universal quantum computer will have fundamental impact on a vast number of research fields and society as a whole. An increasingly large scientific and industrial community is working towards the realization of such a…

Quantum Physics · Physics 2018-11-16 B. Lekitsch , S. Weidt , A. G. Fowler , K. Mølmer , S. J. Devitt , C. Wunderlich , W. K. Hensinger

We aim to advance the state-of-the-art in Quadratic Unconstrained Binary Optimization formulation with a focus on cryptography algorithms. As the minimal QUBO encoding of the linear constraints of optimization problems emerges as the…

Cryptography and Security · Computer Science 2026-04-16 Gregory Morse , Tamás Kozsik , Oskar Mencer , Peter Rakyta