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Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

Machine Learning · Computer Science 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

Quantitative Methods · Quantitative Biology 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

Type 1 diabetes (T1D) is a highly metabolically heterogeneous disease that cannot be adequately characterized by conventional biomarkers such as glycated hemoglobin (HbA1c). This study proposes an explainable deep learning framework that…

Machine Learning · Computer Science 2026-01-09 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba , Sule Yildrim Yayilgan , Sarang Shaikh

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

Machine Learning · Computer Science 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

Machine Learning · Computer Science 2019-07-30 Ramin Ramazi , Christine Perndorfer , Emily Soriano , Jean-Philippe Laurenceau , Rahmatollah Beheshti

Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…

Quantitative Methods · Quantitative Biology 2025-02-04 Soon Jynn Chu , Nalaka Amarasiri , Sandesh Giri , Priyata Kafle

Diabetes mellitus is a global concern, and early detection can prevent serious complications. 50% of people with diabetes live undiagnosed, disproportionately afflicting low-income groups. Non-invasive methods have emerged for timely…

Machine Learning · Computer Science 2023-11-02 Ella Lan

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

While the Artificial Pancreas is effective in regulating the blood glucose in the safe range of 70-180 mg/dl in type 1 diabetic patients, the high intra-patient variability, as well as exogenous meal disturbances, poses a serious challenge.…

Systems and Control · Electrical Eng. & Systems 2022-06-30 Bhabani Shankar Dey , Anirudh Nath , Abhilash Patel , Indra Narayan Kar

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

Machine Learning · Computer Science 2026-03-31 Hai Siong Tan , Rafe McBeth

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…

Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…

Machine Learning · Computer Science 2023-10-24 Harry Emerson , Ryan McConville , Matthew Guy

In this paper, we study the problem of blood glucose forecasting and provide a deep personalized solution. Predicting blood glucose level in people with diabetes has significant value because health complications of abnormal glucose level…

Machine Learning · Computer Science 2021-09-08 Mohammadreza Armandpour , Brian Kidd , Yu Du , Jianhua Z. Huang

In this paper, models of the blood glucose (BG) dynamics in people with Type 1 diabetes (T1D) in response to moderate intensity aerobic activity are derived from physiology-based first principles and system identification experiments. We…

Systems and Control · Electrical Eng. & Systems 2023-07-18 Mehrad Jaloli , Marzia Cescon

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

Machine Learning · Computer Science 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt
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