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Related papers: The Optimization Paradox in Clinical AI Multi-Agen…

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While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud

Background: Globally we face a projected shortage of 11 million healthcare practitioners by 2030, and administrative burden consumes 50% of clinical time. Artificial intelligence (AI) has the potential to help alleviate these problems.…

Human-Computer Interaction · Computer Science 2025-08-01 Hashim Hayat , Maksim Kudrautsau , Evgeniy Makarov , Vlad Melnichenko , Tim Tsykunou , Piotr Varaksin , Matt Pavelle , Adam Z. Oskowitz

As AI agents evolve, the community is rapidly shifting from single Large Language Models (LLMs) to Multi-Agent Systems (MAS) to overcome cognitive bottlenecks in automated research. However, the optimal multi-agent coordination framework…

Multiagent Systems · Computer Science 2026-05-12 Yang Shen , Zhenyi Yi , Ziyi Zhao , Lijun Sun , Dongyang Li , Chin-Teng Lin , Yuhui Shi

AI is increasingly deployed in multi-agent systems; however, most research considers only the behavior of individual models. We experimentally show that multi-agent "AI organizations" are simultaneously more effective at achieving business…

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

The post-pandemic surge in healthcare demand, coupled with critical nursing shortages, has placed unprecedented pressure on medical triage systems, necessitating innovative AI-driven solutions. We present a multi-agent interactive…

Artificial Intelligence · Computer Science 2025-08-05 Hongyan Cheng , Chengzhang Yu , Yanshu Shi , Chiyue Wang , Cong Liu , Zhanpeng Jin

Artificial intelligence in medicine is built to serve the average patient. By minimizing error across large datasets, most systems deliver strong aggregate accuracy yet falter at the margins: patients with rare variants, multimorbidity, or…

Artificial Intelligence · Computer Science 2025-10-29 Pedram Fard , Alaleh Azhir , Neguine Rezaii , Jiazi Tian , Hossein Estiri

Recent advances in the data-driven medicine approach, which integrates ethically managed and explainable artificial intelligence into clinical decision support systems (CDSS), are critical to ensure reliable and effective patient care. This…

Artificial Intelligence · Computer Science 2025-09-23 Ying-Jung Chen , Ahmad Albarqawi , Chi-Sheng Chen

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

Large language models and AI agents have recently shown promise in automating software performance optimization, but existing approaches predominantly rely on local, syntax-driven code transformations. This limits their ability to reason…

Software Engineering · Computer Science 2026-03-17 Huiyun Peng , Parth Vinod Patil , Antonio Zhong Qiu , George K. Thiruvathukal , James C. Davis

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal…

Matching patients effectively and efficiently for clinical trials is a significant challenge due to the complexity and variability of patient profiles and trial criteria. This paper introduces \textbf{Multi-Agent for Knowledge Augmentation…

Multiagent Systems · Computer Science 2026-05-19 Hanwen Shi , Jin Zhang , Kunpeng Zhang

Artificial intelligence (AI) systems in healthcare have demonstrated remarkable potential to improve patient outcomes. However, if not designed with fairness in mind, they also carry the risks of perpetuating or exacerbating existing health…

Machine Learning · Computer Science 2025-01-24 Xiaoyang Wang , Christopher C. Yang

A multi-agent AI system (MAS) is composed of multiple autonomous agents that interact, exchange information, and make decisions based on internal generative models. Recent advances in large language models and tool-using agents have made…

Modern multi-agent systems ranging from sensor networks monitoring critical infrastructure to crowdsourcing platforms aggregating human intelligence can suffer significant performance degradation due to systematic biases that vary with…

Machine Learning · Computer Science 2025-10-31 Siavash M. Alamouti , Fay Arjomandi

Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou

In recent years, the application of generative artificial intelligence (GenAI) in financial analysis and investment decision-making has gained significant attention. However, most existing approaches rely on single-agent systems, which fail…

Artificial Intelligence · Computer Science 2024-11-08 Xuewen Han , Neng Wang , Shangkun Che , Hongyang Yang , Kunpeng Zhang , Sean Xin Xu

Recent work reports strong performance from multi-agent LLM systems (MAS), but these gains are often confounded by increased test-time computation. When computation is normalized, single-agent systems (SAS) can match or outperform MAS, yet…

Computation and Language · Computer Science 2026-04-14 Dat Tran , Douwe Kiela

Autonomous agentic workflows that iteratively refine their own behavior hold considerable promise, yet their failure modes remain poorly characterized. We investigate optimization instability, a phenomenon in which continued autonomous…

Artificial Intelligence · Computer Science 2026-02-19 Cameron Cagan , Pedram Fard , Jiazi Tian , Jingya Cheng , Shawn N. Murphy , Hossein Estiri

Large language model (LLM)-based agents are increasingly used to perform complex, multi-step workflows in regulated settings such as compliance and due diligence. However, many agentic architectures rely primarily on prompt engineering of a…

Artificial Intelligence · Computer Science 2026-02-03 Ananya Joshi , Michael Rudow
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