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The nondestructive imaging of subsurface structures on the nanometer scale has been a long-standing desire in both science and industry. A few impressive images were published so far that demonstrate the general feasibility by combining…

Materials Science · Physics 2017-04-14 G. J. Verbiest , T. H. Oosterkamp , M. J. Rost

Factorization Machines (FMs) are a supervised learning approach that enhances the linear regression model by incorporating the second-order feature interactions. Despite effectiveness, FM can be hindered by its modelling of all feature…

Machine Learning · Computer Science 2017-08-17 Jun Xiao , Hao Ye , Xiangnan He , Hanwang Zhang , Fei Wu , Tat-Seng Chua

We examine the mechanical eigenmodes of a quartz tuning fork (QTF) for the purpose of facilitat- ing its use as a probe for multi-frequency atomic force microscopy (AFM). We perform simulations based on the three-dimensional finite element…

Instrumentation and Detectors · Physics 2017-03-08 Bongsu Kim , Junghoon Jahng , Ryan Muhammad Khan , Sung Park , Eric O. Potma

Atomic force microscope (AFM) users often calibrate the spring constants of cantilevers using functionality built into individual instruments. This is performed without reference to a global standard, which hinders robust comparison of…

In this article, we present a deflection measurement setup for Atomic Force Microscopy (AFM). It is based on a quadrature phase differential interferometer: we measure the optical path difference between a laser beam reflecting above the…

Instrumentation and Detectors · Physics 2015-06-16 Pierdomenico Paolino , Felipe A. Aguilar Sandoval , Ludovic Bellon

Magnetic resonance force microscopy (MRFM) is a scanning probe technique capable of detecting MRI signals from nanoscale sample volumes, providing a paradigm-changing potential for structural biology and medical research. Thus far, however,…

Atom interferometry is a rapidly advancing field and this Letter proposes an experiment based on existing technology that can search for new short distance forces. With current technology it is possible to improve the sensitivity by up to a…

High Energy Physics - Phenomenology · Physics 2014-11-20 Jay G. Wacker

An adaptive modeling method (AMM) that couples a deep neural network potential and a classical force field is introduced to address the accuracy-efficiency dilemma faced by the molecular simulation community. The AMM simulated system is…

Chemical Physics · Physics 2018-11-14 Linfeng Zhang , Han Wang , Weinan E

Molecular-level understanding of the interactions between the constituents of an atomic structure is essential for designing novel materials in various applications. This need goes beyond the basic knowledge of the number and types of…

High-frequency atomic force microscopy has enabled extraordinary new science through large bandwidth, high speed measurements of atomic and molecular structures. However, traditional optical detection schemes restrict the dimensions, and…

Mesoscale and Nanoscale Physics · Physics 2014-03-11 C. Doolin , P. H. Kim , B. D. Hauer , A. J. R MacDonald , J. P Davis

Accelerated magnetic resonance imaging involves reconstructing fully sampled images from undersampled k-space measurements. Current state-of-the-art approaches have mainly focused on either end-to-end supervised training inspired by…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Xinzhe Luo , Yingzhen Li , Chen Qin

The reconstruction task in photoacoustic tomography can vary a lot depending on measured targets, geometry, and especially the quantity we want to recover. Specifically, as the signal is generated due to the coupling of light and sound by…

Medical Physics · Physics 2023-11-28 Andreas Hauptmann , Tanja Tarvainen

Small-amplitude dynamic atomic force microscopy (dynamic-AFM) in a simple nonpolar liquid was studied through molecular dynamics simulations. We find that within linear dynamics regime, the contact stiffness and damping of the confined film…

Materials Science · Physics 2016-05-04 Rong-Guang Xu , Yongsheng Leng

Frequency modulation (FM) Atomic Force Microscopy (AFM) with metal tips functionalized with a CO molecule at the tip apex has provided access to the internal structure of molecules with totally unprecedented resolution. We propose a model…

Materials Science · Physics 2022-05-03 Jaime Carracedo-Cosme , Rubén Pérez

The increasing use of two-dimensional (2D) materials in nanoelectronics demands robust metrology techniques for electrical characterization, especially for large-scale production. While atomic force microscopy (AFM) techniques like…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Levi Harris , Md Jayed Hossain , Mufan Qiu , Ruichen Zhang , Pingchuan Ma , Tianlong Chen , Jiaqi Gu , Seth Ariel Tongay , Umberto Celano

Classical molecular dynamics (MD) simulations enable modeling of materials and examination of microscopic details that are not accessible experimentally. The predictive capability of MD relies on the force field (FF) used to describe…

Shape transformation is crucial for the survival, adaptation, predation, defense, and reproduction of organisms in complex environments. It also serves as a key mechanism for the development of various applications, including soft robotics,…

Applied Physics · Physics 2024-10-17 Xiaoyu Su

Computational prediction of enzyme mechanism and protein function requires accurate physics-based models and suitable sampling. We discuss recent advances in large-scale quantum mechanical (QM) modeling of biochemical systems that have…

Chemical Physics · Physics 2021-05-28 Vyshnavi Vennelakanti , Azadeh Nazemi , Rimsha Mehmood , Adam H. Steeves , Heather J. Kulik

The force sensor is key to the performance of atomic force microscopy (AFM). Nowadays, most AFMs use micro-machined force sensors made from silicon, but piezoelectric quartz sensors are applied at an increasing rate, mainly in vacuum. These…

Mesoscale and Nanoscale Physics · Physics 2015-03-19 Franz J. Giessibl , Florian Pielmeier , Toyoaki Eguchi , Toshu An , Yukio Hasegawa

Pseudo-heterodyne scattering-type scanning near-field optical microscopy (sSNOM) is applied in the mid-infrared region to detect the chemical composition of biomolecules on the nanoscale. However, the application of sSNOM in molecular…

Instrumentation and Detectors · Physics 2025-08-06 Yusuke Sakiyama , Emanuel Pfitzner , Santiago H. Andany , Georg E. Fantner , Joachim Heberle