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Containerization technology offers lightweight OS-level virtualization, and enables portability, reproducibility, and flexibility by packing applications with low performance overhead and low effort to maintain and scale them. Moreover,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-22 Peini Liu , Jordi Guitart

Virtualization enables information and communications technology industry to better manage computing resources. In this regard, improvements in virtualization approaches together with the need for consistent runtime environment, lower…

Cryptography and Security · Computer Science 2021-01-12 Omar Javed , Salman Toor

Container startup latency is a critical performance metric for CI/CD pipelines, serverless computing, and auto-scaling systems, yet practitioners lack empirical guidance on how infrastructure choices affect this latency. We present a…

Performance · Computer Science 2026-02-18 Shamsher Khan

Building and deploying software on high-end computing systems is a challenging task. High performance applications have to reliably run across multiple platforms and environments, and make use of site-specific resources while resolving…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-12 Lucas Benedicic , Felipe A. Cruz , Alberto Madonna , Kean Mariotti

Public cloud computing environments, such as Amazon AWS, Microsoft Azure, and the Google Cloud Platform, have achieved remarkable improvements in computational performance in recent years, and are also expected to be able to perform…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-17 Masahito Ohue , Kento Aoyama , Yutaka Akiyama

Operating System-level virtualization technology, or containers as they are commonly known, represents the next generation of light-weight virtualization, and is primarily represented by Docker. However, Docker's current design does not…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-29 Mudit Verma , Mohan Dhawan

Mobile Edge Computing (MEC) is an emerging network paradigm that provides cloud and IT services at the point of access of the network. Such proximity to the end user translates into ultra-low latency and high bandwidth, while, at the same…

Networking and Internet Architecture · Computer Science 2018-01-29 Giuseppe Avino , Marco Malinverno , Francesco Malandrino , Claudio Casetti , Carla-Fabiana Chiasserini

Solving the software dependency issue under the HPC environment has always been a difficult task for both computing system administrators and application scientists. This work would like to tackle the issue by introducing the modern…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-09-29 Hsi-En Yu , Weicheng Huang

HPC-based applications often have complex workflows with many software dependencies that hinder their portability on contemporary HPC architectures. In addition, these applications often require extraordinary efforts to deploy and execute…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-14 Sameh Abdulah , Jorge Ejarque , Omar Marzouk , Hatem Ltaief , Ying Sun , Marc G. Genton , Rosa M. Badia , David E. Keyes

Microservices are used to build complex applications composed of small, independent and highly decoupled processes. Recently, microservices are often mentioned in one breath with container technologies like Docker. That is why operating…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-12 Nane Kratzke

Molecular docking is a key computational tool utilized to predict the binding conformations of small molecules to protein targets, which is fundamental in the design of novel drugs. Despite recent advancements in geometric deep…

Biomolecules · Quantitative Biology 2023-12-01 Jiaxian Yan , Zaixi Zhang , Kai Zhang , Qi Liu

Deploying complex, distributed scientific workflows across diverse HPC sites is often hindered by site-specific dependencies and complex build environments. This paper investigates the design and performance of portable HPC container images…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-13 Krishna Kant Singh , Eric Müller , Eleni Mathioulaki , Wouter Klijn , Lena Oden

The cloud computing paradigm underlines data center and telecommunication infrastructure design. Heavily leveraging virtualization, it slices hardware and software resources into smaller software units for greater flexibility of…

Networking and Internet Architecture · Computer Science 2026-02-06 Pedro R. X. do Carmo , Eduardo Freitas , Assis T. de Oliveira Filho , Judith Kelner , Djamel Sadok

The ever-increasing complexity of HW/SW systems presents a persistent challenge, particularly in safety-critical domains like automotive, where extensive testing is imperative. However, the availability of hardware often lags behind,…

Software Engineering · Computer Science 2025-06-13 Lukas Jünger , Jan Henrik Weinstock , Tim Kraus

Virtual screening applications are highly parameterized to optimize the balance between quality and execution performance. While output quality is critical, the entire screening process must be completed within a reasonable time. In fact, a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-22 Bruno Guindani , Davide Gadioli , Roberto Rocco , Danilo Ardagna , Gianluca Palermo

The HPC community is actively researching and evaluating tools to support execution of scientific applications in cloud-based environments. Among the various technologies, containers have recently gained importance as they have…

Performance · Computer Science 2019-05-23 Pankaj Saha , Angel Beltre , Piotr Uminski , Madhusudhan Govindaraju

In structure-based drug discovery, virtual screening using conventional molecular docking methods can be performed rapidly but suffers from limitations in prediction accuracy. Recently, Boltz-2 was proposed, achieving extremely high…

Biomolecules · Quantitative Biology 2025-08-26 Kairi Furui , Masahito Ohue

Docker seems to be an attractive solution for cloud database benchmarking as it simplifies the setup process through pre-built images that are portable and simple to maintain. However, the usage of Docker for benchmarking is only valid if…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-12 Martin Grambow , Jonathan Hasenburg , Tobias Pfandzelter , David Bermbach

Accelerating molecular docking -- the process of predicting how molecules bind to protein targets -- could boost small-molecule drug discovery and revolutionize medicine. Unfortunately, current molecular docking tools are too slow to screen…

Vector databases have rapidly grown in popularity, enabling efficient similarity search over data such as text, images, and video. They now play a central role in modern AI workflows, aiding large language models by grounding model outputs…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-17 Seth Ockerman , Amal Gueroudji , Song Young Oh , Robert Underwood , Nicholas Chia , Kyle Chard , Robert Ross , Shivaram Venkataraman