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The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity…

Machine Learning · Computer Science 2024-10-22 Ho-Joon Lee , Prashant S. Emani , Mark B. Gerstein

Virtualization is a key building block of next-generation mobile networks. It can be implemented through two main approaches: traditional virtual machines and lighter-weight containers. Our objective in this paper is to compare these…

Networking and Internet Architecture · Computer Science 2018-09-12 Senay Semu Tadesse , Carla Fabiana Chiasserini , Francesco Malandrino

Currently, many businesses are using cloud computing to obtain an entire IT infrastructure remotely while delegating its management to a third party. The provider of this architecture ensures the operation and maintenance of the services…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-20 Oussama Smimite , Karim Afdel

Cloud computing technology has been one of the most critical developments in provisioning both hardware and software infrastructure in recent years. Container technology is a new cloud technology that boosts the booting of applications,…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-01 Abdullah Alelyani , Ghulam Mubasher Hassan , Amitava Datta

Nowadays distributed computing environments, large amounts of data are generated from different resources with a high velocity, rendering the data difficult to capture, manage, and process within existing relational databases. Hadoop is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-24 Rana Ghazali , Douglas G. Down

Efficient resource allocation is one of the critical performance challenges in an Infrastructure as a Service (IaaS) cloud. Virtual machine (VM) placement and migration decision making methods are integral parts of these resource allocation…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-12-04 Gaurav Somani , Prateek Khandelwal , Kapil Phatnani

The efficiency of current cargo screening processes at sea and air ports is unknown as no benchmarks exists against which they could be measured. Some manufacturer benchmarks exist for individual sensors but we have not found any benchmarks…

Artificial Intelligence · Computer Science 2013-05-31 Peer-Olaf Siebers , Uwe Aickelin , David Menachof , Galina Sherman , Peter Zimmerman

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

The metaverse is regarded as a new wave of technological transformation that provides a virtual space for people to interact through digital avatars. To achieve immersive user experiences in the metaverse, real-time rendering is the key…

Networking and Internet Architecture · Computer Science 2022-04-26 Yuna Jiang , Jiawen Kang , Dusit Niyato , Xiaohu Ge , Zehui Xiong , Chunyan Miao , Xuemin , Shen

Modern Mixed-Criticality Systems (MCSs) rely on hardware heterogeneity to satisfy ever-increasing computational demands. However, most of the heterogeneous co-processors are designed to achieve high throughput, with their…

Hardware Architecture · Computer Science 2024-09-24 Jiapeng Guan , Ran Wei , Dean You , Yingquan Wang , Ruizhe Yang , Hui Wang , Zhe Jiang

Containerisation demonstrates its efficiency in application deployment in cloud computing. Containers can encapsulate complex programs with their dependencies in isolated environments, hence are being adopted in HPC clusters. HPC workload…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-14 Naweiluo Zhou , Yiannis Georgiou , Li Zhong , Huan Zhou , Marcin Pospieszny

Publish/subscribe (pub/sub) networks are a cornerstone of modern distributed systems, playing a crucial role in applications like the Internet of Things (IoT) and robotics. While runtime verification techniques seem ideal for ensuring the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-14 Ali Mehran , Dogan Ulus

Vector quantization(VQ) is a hardware-friendly DNN compression method that can reduce the storage cost and weight-loading datawidth of hardware accelerators. However, conventional VQ techniques lead to significant accuracy loss because the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Shuaiting Li , Chengxuan Wang , Juncan Deng , Zeyu Wang , Zewen Ye , Zongsheng Wang , Haibin Shen , Kejie Huang

Containerization, driven by Docker, has transformed application development and deployment by enhancing efficiency and scalability. However, the rapid adoption of container technologies introduces significant security challenges that…

Cryptography and Security · Computer Science 2025-06-04 Gogulakrishnan Thiyagarajan , Prabhudarshi Nayak

Performance Benchmarking of HPC systems is an ongoing effort that seeks to provide information that will allow for increased performance and improve the job schedulers that manage these systems. We develop a benchmarking tool that utilizes…

Performance · Computer Science 2023-07-28 Warren R. Williams , S. Ross Glandon , Luke L. Morris , Jing-Ru C. Cheng

Hypertext documents, such as web pages and academic papers, are of great importance in delivering information in our daily life. Although being effective on plain documents, conventional text embedding methods suffer from information loss…

Computation and Language · Computer Science 2018-05-11 Jialong Han , Yan Song , Wayne Xin Zhao , Shuming Shi , Haisong Zhang

In the context of self-driving laboratories (SDLs), ensuring automated and error-free capping is crucial, as it is a ubiquitous step in sample preparation. Automated capping in SDLs can occur in both large and small workspaces (e.g., inside…

As heterogeneous supercomputing architectures leveraging GPUs become increasingly central to high-performance computing (HPC), it is crucial for computational fluid dynamics (CFD) simulations, a de-facto HPC workload, to efficiently utilize…

Efficient container image distribution is crucial for enabling machine learning inference at the network edge, where resource limitations and dynamic network conditions create significant challenges. In this paper, we present PeerSync, a…

Networking and Internet Architecture · Computer Science 2025-12-22 Yinuo Deng , Hailiang Zhao , Dongjing Wang , Peng Chen , Wenzhuo Qian , Jianwei Yin , Schahram Dustdar , Shuiguang Deng

Vectors of data are at the heart of machine learning and data mining. Recently, vector quantization methods have shown great promise in reducing both the time and space costs of operating on vectors. We introduce a vector quantization…

Performance · Computer Science 2017-07-03 Davis W Blalock , John V Guttag
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