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Regression-based predictive analytics used in modern kidney transplantation is known to inherit biases from training data. This leads to social discrimination and inefficient organ utilization, particularly in the context of a few social…

Human-Computer Interaction · Computer Science 2025-05-13 Mukund Telukunta , Venkata Sriram Siddhardh Nadendla , Morgan Stuart , Casey Canfield

Demographic parity (DP) is a widely used group fairness criterion requiring predictive distributions to be invariant across sensitive groups. While natural in classification, full distributional DP is often overly restrictive in regression…

Machine Learning · Statistics 2026-03-27 Arthur Charpentier , Christophe Denis , Romuald Elie , Mohamed Hebiri , François HU

The cause-specific cumulative incidence function (CIF) quantifies the subject-specific disease risk with competing risk outcome. With longitudinally collected biomarker data, it is of interest to dynamically update the predicted CIF by…

Quantitative Methods · Quantitative Biology 2019-06-14 Cai Wu , Liang Li , Ruosha Li

We introduce a mixture model for censored durations (C-mix), and develop maximum likelihood inference for the joint estimation of the time distributions and latent regression parameters of the model. We consider a high-dimensional setting,…

Machine Learning · Statistics 2017-11-28 Simon Bussy , Agathe Guilloux , Stéphane Gaïffas , Anne-Sophie Jannot

Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…

While significant progress has been made in specifying neural networks capable of representing uncertainty, deep networks still often suffer from overconfidence and misaligned predictive distributions. Existing approaches for measuring this…

Machine Learning · Computer Science 2025-10-24 Spencer Young , Riley Sinema , Cole Edgren , Andrew Hall , Nathan Dong , Porter Jenkins

In many biomedical applications, outcome is measured as a ``time-to-event'' (eg. disease progression or death). To assess the connection between features of a patient and this outcome, it is common to assume a proportional hazards model,…

Statistics Theory · Mathematics 2020-08-11 Aliasghar Tarkhan , Noah Simon

A foundational problem in reinforcement learning and interactive decision making is to understand what modeling assumptions lead to sample-efficient learning guarantees, and what algorithm design principles achieve optimal sample…

Machine Learning · Computer Science 2023-01-20 Dylan J. Foster , Noah Golowich , Yanjun Han

Given the limited pool of donor organs, accurate predictions of survival on the wait list and post transplantation are crucial for cardiac transplantation decisions and policy. However, current clinical risk scores do not yield accurate…

Applications · Statistics 2017-04-13 J. Yoon , W. R. Zame , A. Banerjee , M. Cadeiras , A. M. Alaa , M. van der Schaar

Proximal causal inference (PCI) is a recently proposed framework to identify and estimate the causal effect of an exposure on an outcome in the presence of hidden confounders, using observed proxies. Specifically, PCI relies on two types of…

Methodology · Statistics 2025-07-29 Prabrisha Rakshit , Xu Shi , Eric Tchetgen Tchetgen

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for…

Statistics Theory · Mathematics 2025-08-06 Antoine Caillebotte , Estelle Kuhn , Sarah Lemler

Credit risk scoring must support high-stakes lending decisions where data distributions change over time, probability estimates must be reliable, and group-level fairness is required. While modern machine learning models improve default…

Risk Management · Quantitative Finance 2026-03-10 Srikumar Nayak

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Machine learning algorithms in socially sensitive domains (e.g., credit decisions) often focus on equalizing predictive outcomes. However, satisfying these metrics does not guarantee that models use the same reasoning for different groups.…

Machine Learning · Computer Science 2026-05-14 Gideon Popoola , John Sheppard

Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

Machine Learning · Computer Science 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

A conditional expectation function (CEF) can at best be partially identified when the conditioning variable is interval censored. When the number of bins is small, existing methods often yield minimally informative bounds. We propose three…

Econometrics · Economics 2018-03-01 Sam Asher , Paul Novosad , Charlie Rafkin

This paper develops a new approach to post-selection inference for screening high-dimensional predictors of survival outcomes. Post-selection inference for right-censored outcome data has been investigated in the literature, but much…

Methodology · Statistics 2021-12-22 Tzu-Jung Huang , Alex Luedtke , Ian W. McKeague

The difference in restricted mean survival times between two groups is a clinically relevant summary measure. With observational data, there may be imbalances in confounding variables between the two groups. One approach to account for such…

Applications · Statistics 2014-10-17 Andrew Wey , David Vock , John Connett , Kyle Rudser

The purpose of this work is to improve the efficiency in estimating the average causal effect (ACE) on the survival scale where right-censoring exists and high-dimensional covariate information is available. We propose new estimators using…

Methodology · Statistics 2021-06-29 Ran Dai , Cheng Zheng , Mei-Jie Zhang

Conventional survival metrics, such as Harrell's concordance index (CI) and the Brier Score, rely on the independent censoring assumption for valid inference with right-censored data. However, in the presence of so-called dependent…

Machine Learning · Statistics 2025-05-20 Christian Marius Lillelund , Shi-ang Qi , Russell Greiner