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We introduce QUANTISENC, a fully configurable open-source software-defined digital quantized spiking neural core architecture to advance research in neuromorphic computing. QUANTISENC is designed hierarchically using a bottom-up methodology…

Large language model (LLM) inference performance is increasingly bottlenecked by the memory wall. While GPUs continue to scale raw compute throughput, they struggle to deliver scalable performance for memory bandwidth bound workloads. This…

Hardware Architecture · Computer Science 2026-02-25 Matthew Adiletta , Gu-Yeon Wei , David Brooks

Many modern workloads such as neural network inference and graph processing are fundamentally memory-bound. For such workloads, data movement between memory and CPU cores imposes a significant overhead in terms of both latency and energy. A…

Hardware Architecture · Computer Science 2023-04-04 Juan Gómez-Luna , Izzat El Hajj , Ivan Fernandez , Christina Giannoula , Geraldo F. Oliveira , Onur Mutlu

Over the last few years, Large Language Models (LLMs) have emerged as a valuable tool for Electronic Design Automation (EDA). State-of-the-art research in LLM-aided design has demonstrated the ability of LLMs to generate syntactically…

Hardware Architecture · Computer Science 2025-07-10 Elisavet Lydia Alvanaki , Kevin Lee , Luca P. Carloni

Generating accurate circuit schematics from high-level natural language descriptions remains a persistent challenge in electronic design automation (EDA), as large language models (LLMs) frequently hallucinate components, violate strict…

Artificial Intelligence · Computer Science 2026-05-28 Khandakar Shakib Al Hasan , Syed Rifat Raiyan , Hasin Mahtab Alvee , Wahid Sadik

Recent advances in generative AI have accelerated the discovery of novel chemicals and materials. However, scaling these discoveries to industrial production remains a major bottleneck due to the synthesis gap -- the need to develop…

Machine Learning · Computer Science 2025-08-19 Sakhinana Sagar Srinivas , Shivam Gupta , Venkataramana Runkana

Large Language Models (LLMs) such as ChatGPT have transformed how we interact with and understand the capabilities of Artificial Intelligence (AI). However, the intersection of LLMs with the burgeoning field of Quantum Machine Learning…

Quantum Physics · Physics 2024-03-15 Yidong Liao , Chris Ferrie

Recent advancements in quantum computing (QC) and machine learning (ML) have fueled significant research efforts aimed at integrating these two transformative technologies. Quantum machine learning (QML), an emerging interdisciplinary…

Quantum Physics · Physics 2025-04-24 Samuel Yen-Chi Chen , Zhiding Liang

The increasing complexity of modern very-large-scale integration (VLSI) design highlights the significance of Electronic Design Automation (EDA) technologies. Chip placement is a critical step in the EDA workflow, which positions chip…

Quantum computing promises to revolutionize various fields, yet the execution of quantum programs necessitates an effective compilation process. This involves strategically mapping quantum circuits onto the physical qubits of a quantum…

Quantum Physics · Physics 2024-12-19 Tian Li , Xiao-Yue Xu , Chen Ding , Tian-Ci Tian , Wei-You Liao , Shuo Zhang , He-Liang Huang

Reasoning is central to a wide range of intellectual activities, and while the capabilities of large language models (LLMs) continue to advance, their performance in reasoning tasks remains limited. The processes and mechanisms underlying…

Artificial Intelligence · Computer Science 2024-10-07 Ippei Fujisawa , Sensho Nobe , Hiroki Seto , Rina Onda , Yoshiaki Uchida , Hiroki Ikoma , Pei-Chun Chien , Ryota Kanai

Large Language Models (LLMs) have recently shown promise in streamlining hardware design processes by encapsulating vast amounts of domain-specific data. In addition, they allow users to interact with the design processes through natural…

Machine Learning · Computer Science 2024-07-04 Yongan Zhang , Zhongzhi Yu , Yonggan Fu , Cheng Wan , Yingyan Celine Lin

The integration of Large Language Models (LLMs) into software engineering has driven a transition from traditional rule-based systems to autonomous agentic systems capable of solving complex problems. However, systematic progress is…

Software Engineering · Computer Science 2025-10-24 Jiale Guo , Suizhi Huang , Mei Li , Dong Huang , Xingsheng Chen , Regina Zhang , Zhijiang Guo , Han Yu , Siu-Ming Yiu , Pietro Lio , Kwok-Yan Lam

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

The resurgence of near-memory processing (NMP) with the advent of big data has shifted the computation paradigm from processor-centric to memory-centric computing. To meet the bandwidth and capacity demands of memory-centric computing, 3D…

Hardware Architecture · Computer Science 2021-04-29 Pritam Majumder , Jiayi Huang , Sungkeun Kim , Abdullah Muzahid , Dylan Siegers , Chia-Che Tsai , Eun Jung Kim

Multimodal Large Language Models (MLLMs) have experienced significant advancements recently. Nevertheless, challenges persist in the accurate recognition and comprehension of intricate details within high-resolution images. Despite being…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Haogeng Liu , Quanzeng You , Xiaotian Han , Yiqi Wang , Bohan Zhai , Yongfei Liu , Yunzhe Tao , Huaibo Huang , Ran He , Hongxia Yang

Protein design aims to compose amino-acid sequences that fold into stable three-dimensional structures while satisfying targeted functional properties. The field is increasingly shifting toward vibe protein design, where a single model is…

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

In this work, we propose an architecture and methodology to design hardware/software systems for high-performance embedded computing on FPGA. The hardware side is based on a many-core architecture whose design is generated automatically…

Hardware Architecture · Computer Science 2015-08-28 Mário P. Véstias , Rui Policarpo Duarte , Horácio C. Neto