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Uncertainty quantification is becoming increasingly important in image segmentation, especially for high-stakes applications like medical imaging. While conformal risk control generalizes conformal prediction beyond standard miscoverage to…

Machine Learning · Computer Science 2025-04-11 Rui Luo , Zhixin Zhou

In recent years, convolutional neural networks have demonstrated promising performance in a variety of medical image segmentation tasks. However, when a trained segmentation model is deployed into the real clinical world, the model may not…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Shuo Wang , Giacomo Tarroni , Chen Qin , Yuanhan Mo , Chengliang Dai , Chen Chen , Ben Glocker , Yike Guo , Daniel Rueckert , Wenjia Bai

Identification and quantification of myocardial scar is important for diagnosis and prognosis of cardiovascular diseases. However, reliable scar segmentation from Late Gadolinium Enhancement Cardiac Magnetic Resonance (LGE-CMR) images…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Nivetha Jayakumar , Jonathan Pan , Shuo Wang , Bishow Paudel , Nisha Hosadurg , Cristiane C. Singulane , Sivam Bhatt , Amit R. Patel , Miaomiao Zhang

Conformal prediction provides a distribution-free framework for uncertainty quantification via prediction sets with exact finite-sample coverage. In low dimensions these sets are easy to interpret, but in high-dimensional or structured…

Machine Learning · Statistics 2026-05-08 Trevor Harris

Conformal prediction is a learning framework controlling prediction coverage of prediction sets, which can be built on any learning algorithm for point prediction. This work proposes a learning framework named conformal loss-controlling…

Machine Learning · Computer Science 2024-01-24 Di Wang , Ping Wang , Zhong Ji , Xiaojun Yang , Hongyue Li

Conformal prediction is a distribution-free and model-agnostic uncertainty-quantification method that provides finite-sample prediction intervals with guaranteed coverage. In this work, for the first time, we apply conformal-prediction to…

Nuclear Theory · Physics 2026-02-02 Habib Yousefi Dezdarani , Ryan Curry , Alexandros Gezerlis

The hybrid clustering-classification neural network is proposed. This network allows increasing a quality of information processing under the condition of overlapping classes due to the rational choice of a learning rate parameter and…

Machine Learning · Computer Science 2016-10-26 Yevgeniy Bodyanskiy , Olena Vynokurova , Volodymyr Savvo , Tatiana Tverdokhlib , Pavlo Mulesa

Conformal predictive systems allow forecasters to issue predictive distributions for real-valued future outcomes that have out-of-sample calibration guarantees. On a more abstract level, conformal prediction makes use of in-sample…

Methodology · Statistics 2025-03-07 Sam Allen , Georgios Gavrilopoulos , Alexander Henzi , Gian-Reto Kleger , Johanna Ziegel

Conformal prediction is a statistically rigorous method for quantifying uncertainty in models by having them output sets of predictions, with larger sets indicating more uncertainty. However, prediction sets are not inherently actionable;…

Machine Learning · Computer Science 2025-02-17 Jesse C. Cresswell , Bhargava Kumar , Yi Sui , Mouloud Belbahri

Calibration ensures that probabilistic forecasts meaningfully capture uncertainty by requiring that predicted probabilities align with empirical frequencies. However, many existing calibration methods are specialized for post-hoc…

Machine Learning · Computer Science 2023-11-01 Charles Marx , Sofian Zalouk , Stefano Ermon

This project intends to study a cardiovascular disease risk early warning model based on one-dimensional convolutional neural networks. First, the missing values of 13 physiological and symptom indicators such as patient age, blood glucose,…

Machine Learning · Computer Science 2024-06-14 Yuxiang Hu , Jinxin Hu , Ting Xu , Bo Zhang , Jiajie Yuan , Haozhang Deng

In regression, conformal prediction is a general methodology to construct prediction intervals in a distribution-free manner. Although conformal prediction guarantees strong statistical property for predictive inference, its inherent…

Statistics Theory · Mathematics 2016-12-01 Wenyu Chen , Zhaokai Wang , Wooseok Ha , Rina Foygel Barber

Future trajectories play an important role across domains such as autonomous driving, hurricane forecasting, and epidemic modeling, where practitioners commonly generate ensemble paths by sampling probabilistic models or leveraging multiple…

Machine Learning · Computer Science 2025-08-20 Ruipu Li , Daniel Menacho , Alexander Rodríguez

Early detection and diagnosis of coronary artery disease (CAD) could save lives and reduce healthcare costs. The current clinical practice is to perform CAD diagnosis through analysing medical images from computed tomography coronary…

Most machine learning-based image segmentation models produce pixel-wise confidence scores that represent the model's predicted probability for each class label at every pixel. While this information can be particularly valuable in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Bruno Viti , Elias Karabelas , Martin Holler

Conformal Prediction (CP) algorithms estimate the uncertainty of a prediction model by calibrating its outputs on labeled data. The same calibration scheme usually applies to any model and data without modifications. The obtained prediction…

Machine Learning · Computer Science 2024-06-27 Nicolo Colombo

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

In cluster-randomized trials (CRTs), entire clusters of individuals are randomized to treatment, and outcomes within a cluster are typically correlated. While frequentist approaches are standard practice for CRT analysis, Bayesian methods…

Methodology · Statistics 2025-11-27 Ruyi Liu , Joshua L. Warren , Yuki Ohnishi , Donna Spiegelman , Liangyuan Hu , Fan Li

This paper applies conformal prediction techniques to compute simultaneous prediction bands and clustering trees for functional data. These tools can be used to detect outliers and clusters. Both our prediction bands and clustering trees…

Machine Learning · Statistics 2013-02-27 Jing Lei , Alessandro Rinaldo , Larry Wasserman

Simulations of coronary hemodynamics have improved non-invasive clinical risk stratification and treatment outcomes for coronary artery disease, compared to relying on anatomical imaging alone. However, simulations typically use empirical…