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This paper is a cursory study on how topological features are preserved within the internal representations of neural network layers. Using techniques from topological data analysis, namely persistent homology, the topological features of a…

Machine Learning · Computer Science 2022-08-16 Archie Shahidullah

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

We propose a novel approach for preserving topological structures of the input space in latent representations of autoencoders. Using persistent homology, a technique from topological data analysis, we calculate topological signatures of…

Machine Learning · Computer Science 2021-06-01 Michael Moor , Max Horn , Bastian Rieck , Karsten Borgwardt

Transformer layers, which use an alternating pattern of multi-head attention and multi-layer perceptron (MLP) layers, provide an effective tool for a variety of machine learning problems. As the transformer layers use residual connections…

Machine Learning · Computer Science 2022-12-13 Yaofeng Desmond Zhong , Tongtao Zhang , Amit Chakraborty , Biswadip Dey

Classical unsupervised learning methods like clustering and linear dimensionality reduction parametrize large-scale geometry when it is discrete or linear, while more modern methods from manifold learning find low dimensional representation…

Machine Learning · Computer Science 2025-09-23 Luis Scoccola , Uzu Lim , Heather A. Harrington

Multilayer networks have become increasingly ubiquitous across diverse scientific fields, ranging from social sciences and biology to economics and international relations. Despite their broad applications, the inferential theory for…

Methodology · Statistics 2026-02-24 Zhaozhe Liu , Gongjun Xu , Haoran Zhang

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Due to their ability to model meaningful higher order relations among a set of entities, higher order network models have emerged recently as a powerful alternative for graph-based network models which are only capable of modeling binary…

Machine Learning · Computer Science 2023-12-20 Karthikeyan Natesan Ramamurthy , Aldo Guzmán-Sáenz , Mustafa Hajij

Summarizing topological information from datasets and maps defined on them is a central theme in topological data analysis. \textsf{Mapper}, a tool for such summarization, takes as input both a possibly high dimensional dataset and a map…

Computational Geometry · Computer Science 2016-01-13 Tamal K. Dey , Facundo Memoli , Yusu Wang

In this paper, we present SIMAP, a novel layer integrated into deep learning models, aimed at enhancing the interpretability of the output. The SIMAP layer is an enhanced version of Simplicial-Map Neural Networks (SMNNs), an explainable…

Machine Learning · Computer Science 2024-03-25 Rocio Gonzalez-Diaz , Miguel A. Gutiérrez-Naranjo , Eduardo Paluzo-Hidalgo

We propose PLLay, a novel topological layer for general deep learning models based on persistence landscapes, in which we can efficiently exploit the underlying topological features of the input data structure. In this work, we show…

Machine Learning · Computer Science 2021-01-19 Kwangho Kim , Jisu Kim , Manzil Zaheer , Joon Sik Kim , Frederic Chazal , Larry Wasserman

The manifold hypothesis, which assumes that data lies on or close to an unknown manifold of low intrinsic dimension, is a staple of modern machine learning research. However, recent work has shown that real-world data exhibits distinct…

Machine Learning · Computer Science 2023-06-16 Julius von Rohrscheidt , Bastian Rieck

Multiparameter persistent homology has been largely neglected as an input to machine learning algorithms. We consider the use of lattice-based convolutional neural network layers as a tool for the analysis of features arising from…

Algebraic Topology · Mathematics 2022-09-01 Hans Riess , Jakob Hansen , Robert Ghrist

Latent space models are frequently used for modeling single-layer networks and include many popular special cases, such as the stochastic block model and the random dot product graph. However, they are not well-developed for more complex…

Methodology · Statistics 2021-07-09 Peter W. MacDonald , Elizaveta Levina , Ji Zhu

The ability of neural networks to represent more features than neurons makes interpreting them challenging. This phenomenon, known as superposition, has spurred efforts to find architectures that are more interpretable than standard…

Machine Learning · Computer Science 2023-05-08 Lee Sharkey

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

Topological features play an essential role in ensuring geometric plausibility and structural consistency in image analysis tasks such as segmentation and skeletonization. However, integrating topology-preserving learning based on simple…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Wenxiao Li , Faqiang Wang , Yuping Duan , Li Cui , Liqiang Zhang , Jun Liu

Using a set of $\Lambda$CDM simulations of cosmic structure formation, we study the evolving connectivity and changing topological structure of the cosmic web using state-of-the-art tools of multiscale topological data analysis (TDA). We…

Artificial neural networks can learn complex, salient data features to achieve a given task. On the opposite end of the spectrum, mathematically grounded methods such as topological data analysis allow users to design analysis pipelines…

Machine Learning · Computer Science 2022-12-29 Mattia G. Bergomi , Massimo Ferri , Alessandro Mella , Pietro Vertechi
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