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Contrastive learning has emerged as an essential approach for self-supervised learning in visual representation learning. The central objective of contrastive learning is to maximize the similarities between two augmented versions of an…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Hengkui Dong , Xianzhong Long , Yun Li , Lei Chen

The recent advances in single-cell technologies have enabled us to profile genomic features at unprecedented resolution and datasets from multiple domains are available, including datasets that profile different types of genomic features…

Machine Learning · Statistics 2020-06-09 Pengcheng Zeng , Zhixiang Lin

Understanding the intricate cellular environment within biological tissues is crucial for uncovering insights into complex biological functions. While single-cell RNA sequencing has significantly enhanced our understanding of cellular…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Bingjun Li , Mostafa Karami , Masum Shah Junayed , Sheida Nabavi

Subspace clustering methods based on data self-expression have become very popular for learning from data that lie in a union of low-dimensional linear subspaces. However, the applicability of subspace clustering has been limited because…

Computer Vision and Pattern Recognition · Computer Science 2019-05-02 Junjian Zhang , Chun-Guang Li , Chong You , Xianbiao Qi , Honggang Zhang , Jun Guo , Zhouchen Lin

Deep clustering has been dominated by flat models, which split a dataset into a predefined number of groups. Although recent methods achieve an extremely high similarity with the ground truth on popular benchmarks, the information contained…

Machine Learning · Computer Science 2023-06-22 Michał Znaleźniak , Przemysław Rola , Patryk Kaszuba , Jacek Tabor , Marek Śmieja

Single-cell RNA sequencing (scRNA-seq) has transformed our ability to explore biological systems. Nevertheless, proficient expertise is essential for handling and interpreting the data. In this paper, we present scX, an R package built on…

Self-supervised hyperspectral image (HSI) clustering remains a fundamental yet challenging task due to the absence of labeled data and the inherent complexity of spatial-spectral interactions. While recent advancements have explored…

Image and Video Processing · Electrical Eng. & Systems 2025-02-10 Yao Ding , Zhili Zhang , Aitao Yang , Yaoming Cai , Xiongwu Xiao , Danfeng Hong , Junsong Yuan

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

Identifying unique characteristics in a network through comparison with another network is an essential network analysis task. For example, with networks of protein interactions obtained from normal and cancer tissues, we can discover…

Machine Learning · Computer Science 2022-02-16 Takanori Fujiwara , Jian Zhao , Francine Chen , Yaoliang Yu , Kwan-Liu Ma

Heterogeneous graphs (HGs) are composed of multiple types of nodes and edges, making it more effective in capturing the complex relational structures inherent in the real world. However, in real-world scenarios, labeled data is often…

Machine Learning · Computer Science 2025-08-20 Ruobing Jiang , Yacong Li , Haobing Liu , Yanwei Yu

Single cell combinatorial indexing RNA sequencing (sci-RNA-seq) is a powerful method for recovering gene expression data from an exponentially scalable number of individual cells or nuclei. However, sci-RNA-seq is a complex protocol that…

Summary: Accurate phenotype prediction from genomic sequences is a highly coveted task in biological and medical research. While machine-learning holds the key to accurate prediction in a variety of fields, the complexity of biological data…

In this thesis, we propose several modelling strategies to tackle evolving data in different contexts. In the framework of static clustering, we start by introducing a soft kernel spectral clustering (SKSC) algorithm, which can better deal…

Social and Information Networks · Computer Science 2014-11-24 Rocco Langone

Single-cell RNA sequencing (scRNA-seq) technology has profiled hundreds of millions of human cells across organs, diseases, development and perturbations to date. However, the high-dimensional sparsity, batch effect noise, category…

Machine Learning · Computer Science 2025-03-07 Zhen Yu , Jianan Han , Yang Liu , Qingchao Chen

Many methods have been proposed for removing batch effects and aligning single-cell RNA (scRNA) datasets. However, performance is typically evaluated based on multiple parameters and few datasets, creating challenges in assessing which…

Machine Learning · Computer Science 2025-03-27 Juan Javier Diaz-Mejia , Elias Williams , Octavian Focsa , Dylan Mendonca , Swechha Singh , Brendan Innes , Sam Cooper

Comparisons of single-cell RNA sequencing (scRNA-seq) data across species can reveal links between cellular gene expression and the evolution of cell functions, features, and phenotypes. These comparisons invoke evolutionary histories, as…

Populations and Evolution · Quantitative Biology 2023-07-07 Samuel H. Church , Jasmine L. Mah , Casey W. Dunn

This work aims at improving instance retrieval with self-supervision. We find that fine-tuning using the recently developed self-supervised (SSL) learning methods, such as SimCLR and MoCo, fails to improve the performance of instance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Zelu Deng , Yujie Zhong , Sheng Guo , Weilin Huang

Contrastive Learning (CL) enhances the training of sequential recommendation (SR) models through informative self-supervision signals. Existing methods often rely on data augmentation strategies to create positive samples and promote…

Information Retrieval · Computer Science 2026-04-06 Zhikai Wang , Yanyan Shen , Zexi Zhang , Li He , Yichun Li , Hao Gu , Yinghua Zhang

Graph Contrastive Learning (GCL) excels at managing noise and fluctuations in input data, making it popular in various fields (e.g., social networks, and knowledge graphs). Our study finds that the difference in high-frequency information…

Machine Learning · Computer Science 2024-10-15 Yuntao Shou , Xiangyong Cao , Deyu Meng

Semi-supervised learning acts as an effective way to leverage massive unlabeled data. In this paper, we propose a novel training strategy, termed as Semi-supervised Contrastive Learning (SsCL), which combines the well-known contrastive loss…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Yuhang Zhang , Xiaopeng Zhang , Robert. C. Qiu , Jie Li , Haohang Xu , Qi Tian
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