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Background: Ontologies are fundamental components of informatics infrastructure in domains such as biomedical, environmental, and food sciences, representing consensus knowledge in an accurate and computable form. However, their…
Retrieval-Augmented Generation (RAG) methods augment the input of Large Language Models (LLMs) with relevant retrieved passages, reducing factual errors in knowledge-intensive tasks. However, contemporary RAG approaches suffer from…
Recent advances in large language models (LLMs) have fueled the vision of automated scientific discovery, often called AI Co-Scientists. To date, prior work casts these systems as generative co-authors responsible for crafting hypotheses,…
Terpenoids are a crucial class of natural products that have been studied for over 150 years, but their interdisciplinary nature (spanning chemistry, pharmacology, and biology) complicates knowledge integration. To address this, the authors…
Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…
As the volume of published scholarly literature continues to grow, finding relevant literature becomes increasingly difficult. With the rise of generative Artificial Intelligence (AI), and particularly Large Language Models (LLMs), new…
Retrieval-Augmented Generation (RAG) encounters efficiency challenges when scaling to massive knowledge bases while preserving contextual relevance. We propose Hash-RAG, a framework that integrates deep hashing techniques with systematic…
The integration of retrieval-augmented techniques with LLMs has shown promise in improving performance across various domains. However, their utility in tasks requiring advanced reasoning, such as generating and evaluating mathematical…
Introduction: Generative artificial intelligence (AI), particularly large language models (LLMs), holds significant promise for Health Economics and Outcomes Research (HEOR). However, standardized reporting guidance for LLM-assisted…
This paper presents the development of an AI powered software platform that leverages advanced large language models (LLMs) to transform technology scouting and solution discovery in industrial R&D. Traditional approaches to solving complex…
Large Language Models (LLMs) demonstrate remarkable capabilities but remain limited by their reliance on static training data. Retrieval-Augmented Generation (RAG) addresses this constraint by retrieving external knowledge during inference,…
While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…
Recent advancements in large language models (LLMs) and multi-modal LLMs have been remarkable. However, these models still rely solely on their parametric knowledge, which limits their ability to generate up-to-date information and…
The rapid evolution of artificial intelligence, particularly large language models, presents unprecedented opportunities for materials science research. We proposed and developed an AI materials scientist named MatPilot, which has shown…
Large Language Models (LLM) are disrupting science and research in different subjects and industries. Here we report a minimum-viable-product (MVP) web application called $\textbf{ScienceSage}$. It leverages generative artificial…
Retrieval Augmented Generation (RAG) frameworks have shown significant promise in leveraging external knowledge to enhance the performance of large language models (LLMs). However, conventional RAG methods often retrieve documents based…
Gene set analysis is a mainstay of functional genomics, but it relies on curated databases of gene functions that are incomplete. Here we evaluate five Large Language Models (LLMs) for their ability to discover the common biological…
Retrieval-augmented generation (RAG) has demonstrated effectiveness in mitigating the hallucination problem of large language models (LLMs). However, the difficulty of aligning the retriever with the diverse LLMs' knowledge preferences…
The "AI Scientist" paradigm is transforming scientific research by automating key stages of the research process, from idea generation to scholarly writing. This shift is expected to accelerate discovery and expand the scope of scientific…
Answering multi-hop reasoning questions requires retrieving and synthesizing information from diverse sources. Large Language Models (LLMs) struggle to perform such reasoning consistently. Here we propose an approach to pinpoint and rectify…