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We investigate novel protocols for entanglement purification of qubit Bell pairs. Employing genetic algorithms for the design of the purification circuit, we obtain shorter circuits achieving higher success rates and better final fidelities…

Quantum Physics · Physics 2019-02-22 Stefan Krastanov , Victor V. Albert , Liang Jiang

Protein identification and profiling is critical for the advancement of cell and molecular biology as well as medical diagnostics. Although mass spectrometry and protein microarrays are commonly used for protein identification, both methods…

Diffusion models have achieved great success in image generation tasks. However, the lengthy denoising process and complex neural networks hinder their low-latency applications in real-world scenarios. Quantization can effectively reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xuewen Liu , Zhikai Li , Junrui Xiao , Mengjuan Chen , Jianquan Li , Qingyi Gu

Identifying and counting blood components such as red blood cells, various types of white blood cells, and platelets is a critical task for healthcare practitioners. Deep learning approaches, particularly convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 H. Martin Gillis , Yogeshwar Shendye , Paul Hollensen , Alan Fine , Thomas Trappenberg

Cryogenic Electron Tomography (CryoET) combined with sub-volume averaging (SVA) is the only imaging modality capable of resolving protein structures inside cells at molecular resolution. Particle picking, the task of localizing and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Linhan Wang , Jianwen Dou , Wang Li , Shengkun Wang , Zhiwu Xie , Chang-Tien Lu , Yinlin Chen

Attention-based deep networks have been successfully applied on textual data in the field of NLP. However, their application on protein sequences poses additional challenges due to the weak semantics of the protein words, unlike the plain…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , Akshay Deepak

Objective: Latent diffusion models (LDMs) could mitigate data scarcity challenges affecting machine learning development for medical image interpretation. The recent CCELLA LDM improved prostate cancer detection performance using synthetic…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Emerson P. Grabke , Babak Taati , Masoom A. Haider

Training in unsupervised time series anomaly detection is constantly plagued by the discrimination between harmful `anomaly contaminations' and beneficial `hard normal samples'. These two samples exhibit analogous loss behavior that…

Machine Learning · Computer Science 2026-03-17 Ruyi Zhang , Hongzuo Xu , Songlei Jian , Yusong Tan , Haifang Zhou , Rulin Xu

The design of \emph{de novo} functional proteins that bind specific ligand molecules is paramount in therapeutics and bio-engineering. A critical yet formidable task in this endeavor is the design of the protein pocket, which is the cavity…

Biomolecules · Quantitative Biology 2023-10-23 Zaixi Zhang , Zepu Lu , Zhongkai Hao , Marinka Zitnik , Qi Liu

Large language models have driven significant progress in natural language processing, but their deployment requires substantial compute and memory resources. As models scale, compression techniques become essential for balancing model…

Machine Learning · Computer Science 2025-05-13 Vithursan Thangarasa , Ganesh Venkatesh , Mike Lasby , Nish Sinnadurai , Sean Lie

Deep generative models are often trained on sensitive data, such as genetic sequences, health data, or more broadly, any copyrighted, licensed or protected content. This raises critical concerns around privacy-preserving synthetic data, and…

Large language models (LLMs) have significantly advanced the natural language processing paradigm but impose substantial demands on memory and computational resources. Quantization is one of the most effective ways to reduce memory…

Machine Learning · Computer Science 2025-04-29 Xilong Xie , Liang Wang , Limin Xiao , Meng Han , Lin Sun , Shuai Zheng , Xiangrong Xu

This paper presents a novel method for utilizing fine-tuned Large Language Models (LLMs) to minimize data requirements in load profile analysis, demonstrated through the restoration of missing data in power system load profiles. A two-stage…

Machine Learning · Computer Science 2024-06-05 Yi Hu , Hyeonjin Kim , Kai Ye , Ning Lu

Two-dimensional electrophoresis of proteins has preceded, and accompanied, the birth of proteomics. Although it is no longer the only experimental scheme used in modern proteomics, it still has distinct features and advantages. The purpose…

Genomics · Quantitative Biology 2011-09-15 Thierry Rabilloud , Cécile Lelong

Dataset pruning reduces the storage and training costs of deep learning by selecting an informative subset from a large dataset. However, most existing pruning methods require fully labeled data, which limits their applicability in…

Machine Learning · Computer Science 2026-05-25 Yeseul Cho , Baekrok Shin , Changmin Kang , Chulhee Yun

The rapidly increasing size of large language models (LLMs) presents significant challenges in memory usage and computational costs. Quantizing both weights and activations can address these issues, with hardware-supported fine-grained…

Computation and Language · Computer Science 2025-07-25 Wonsuk Jang , Thierry Tambe

Mass spectrometry based clinical proteomics has emerged as a powerful tool for highthroughput protein profiling and biomarker discovery. Recent improvements in mass spectrometry technology have boosted the potential of proteomic studies in…

Methodology · Statistics 2016-02-10 Alexia Kakourou , Werner Vach , Simone Nicolardi , Yuri van der Burgt , Bart Mertens

Although larger datasets are crucial for training large deep models, the rapid growth of dataset size has brought a significant challenge in terms of considerable training costs, which even results in prohibitive computational expenses.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Sheng-Feng Yu , Jia-Jiun Yao , Wei-Chen Chiu

In this work we explore the fidelity of numerical approximations to the analytic spectra of hyperbolic partial differential equation systems with variable coefficients. We are particularly interested in the ability of discrete methods to…

Numerical Analysis · Mathematics 2025-08-12 Brittany A. Erickson

As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Adrian Galdran , Miguel A. González Ballester