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The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Despite the success of deep neural networks in medical image classification, the problem remains challenging as data annotation is time-consuming, and the class distribution is imbalanced due to the relative scarcity of diseases. To address…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Zhongzheng Huang , Jiawei Wu , Tao Wang , Zuoyong Li , Anastasia Ioannou

Segmentation of pathological images is a crucial step for accurate cancer diagnosis. However, acquiring dense annotations of such images for training is labor-intensive and time-consuming. To address this issue, Semi-Supervised Learning…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Lanfeng Zhong , Xin Liao , Shaoting Zhang , Guotai Wang

Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Tong Shu , Jun Shi , Dongdong Sun , Zhiguo Jiang , Yushan Zheng

In the intelligent diagnosis of bimodal (gray-scale and contrast-enhanced) ultrasound videos, medical domain knowledge such as the way sonographers browse videos, the particular areas they emphasize, and the features they pay special…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Chengqian Zhao , Zhao Yao , Zhaoyu Hu , Yuanxin Xie , Yafang Zhang , Yuanyuan Wang , Shuo Li , Jianhua Zhou , Jianqiao Zhou , Yin Wang , Jinhua Yu

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

The visual examination of tissue biopsy sections is fundamental for cancer diagnosis, with pathologists analyzing sections at multiple magnifications to discern tumor cells and their subtypes. However, existing attention-based multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Olga Fourkioti , Matt De Vries , Chen Jin , Daniel C. Alexander , Chris Bakal

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

With basic Semi-Supervised Object Detection (SSOD) techniques, one-stage detectors generally obtain limited promotions compared with two-stage clusters. We experimentally find that the root lies in two kinds of ambiguities: (1) Selection…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Chang Liu , Weiming Zhang , Xiangru Lin , Wei Zhang , Xiao Tan , Junyu Han , Xiaomao Li , Errui Ding , Jingdong Wang

Semi-supervised learning has proven highly effective in tackling the challenge of limited labeled training data in medical image segmentation. In general, current approaches, which rely on intra-image pixel-wise consistency training via…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Han Wu , Chong Wang , Zhiming Cui

The high-dimensional features extracted from large-scale unlabeled data via various pretrained models with diverse architectures are referred to as heterogeneous multiview data. Most existing unsupervised transfer learning methods fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Jie Chen , Yuanbiao Gou , Chuanbin Liu , Zhu Wang , Xi Peng

Recent advancements in weakly-supervised video anomaly detection have achieved remarkable performance by applying the multiple instance learning paradigm based on multimodal foundation models such as CLIP to highlight anomalous instances…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Wenti Yin , Huaxin Zhang , Xiang Wang , Yuqing Lu , Yicheng Zhang , Bingquan Gong , Jialong Zuo , Li Yu , Changxin Gao , Nong Sang

Although multiple instance learning (MIL) methods are widely used for automatic tumor detection on whole slide images (WSI), they suffer from the extreme class imbalance within the small tumor WSIs. This occurs when the tumor comprises only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Shuo Niu , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Universal models for medical image segmentation, such as interactive and in-context learning (ICL) models, offer strong generalization but require extensive annotations. Interactive models need repeated user prompts for each image, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Jinyan Zhou , Jianfeng Cao , Hanyang Peng , Ting Ma

Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Few-shot learning (FSL) aims to generalize to novel categories with only a few samples. Recent approaches incorporate large language models (LLMs) to enrich visual representations with semantic embeddings derived from class names. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Wenhao Li , Xianjing Meng , Qiangchang Wang , Zhongyi Han , Zhibin Wu , Yilong Yin

Deep learning techniques have been widely applied to hyperspectral image (HSI) classification and have achieved great success. However, the deep neural network model has a large parameter space and requires a large number of labeled data.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Qiqi Zhu , Weihuan Deng , Zhuo Zheng , Yanfei Zhong , Qingfeng Guan , Weihua Lin , Liangpei Zhang , Deren Li

Zero-Shot Learning (ZSL) is achieved via aligning the semantic relationships between the global image feature vector and the corresponding class semantic descriptions. However, using the global features to represent fine-grained images may…

Computer Vision and Pattern Recognition · Computer Science 2018-05-22 Yunlong Yu , Zhong Ji , Yanwei Fu , Jichang Guo , Yanwei Pang , Zhongfei Zhang

Weakly supervised semantic segmentation (WSSS) trains dense pixel-level segmentation models from partial or coarse annotations such as bounding boxes, scribbles, or image-level tags. While recent work leverages foundation models such as the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Stefano Colamonaco , Andrei-Bogdan Florea , Jaron Maene