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Weakly supervised semantic segmentation (WSSS) approaches typically rely on class activation maps (CAMs) for initial seed generation, which often fail to capture global context due to limited supervision from image-level labels. To address…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Soojin Jang , Jungmin Yun , Junehyoung Kwon , Eunju Lee , Youngbin Kim

Image segmentation is one of the most essential biomedical image processing problems for different imaging modalities, including microscopy and X-ray in the Internet-of-Medical-Things (IoMT) domain. However, annotating biomedical images is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Ziyuan Zhao , Zeng Zeng , Kaixin Xu , Cen Chen , Cuntai Guan

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

As advanced image manipulation techniques emerge, detecting the manipulation becomes increasingly important. Despite the success of recent learning-based approaches for image manipulation detection, they typically require expensive…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yuanhao Zhai , Tianyu Luan , David Doermann , Junsong Yuan

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Multiple instance learning (MIL) is a powerful approach to classify whole slide images (WSIs) for diagnostic pathology. A fundamental challenge of MIL on WSI classification is to discover the \textit{critical instances} that trigger the bag…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Zhikang Wang , Yue Bi , Tong Pan , Xiaoyu Wang , Chris Bain , Richard Bassed , Seiya Imoto , Jianhua Yao , Jiangning Song

Semi-supervised medical image segmentation (SSMIS) uses consistency learning to regularize model training, which alleviates the burden of pixel-wise manual annotations. However, it often suffers from error supervision from low-quality…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Qingtao Pan , Wenhao Qiao , Jingjiao Lou , Bing Ji , Shuo Li

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Attention mechanisms is frequently used to learn the discriminative features for better feature representations. In this paper, we extend the attention mechanism to the task of weakly supervised object localization (WSOL) and propose the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Junhui Yin , Siqing Zhang , Dongliang Chang , Zhanyu Ma , Jun Guo

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Lifelong learning on Whole Slide Images (WSIs) aims to train or fine-tune a unified model sequentially on cancer-related tasks, reducing the resources and effort required for data transfer and processing, especially given the gigabyte-scale…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Doanh C. Bui , Ba Hung Ngo , Hoai Luan Pham , Khang Nguyen , Maï K. Nguyen , Yasuhiko Nakashima

Labeling medical images depends on professional knowledge, making it difficult to acquire large amount of annotated medical images with high quality in a short time. Thus, making good use of limited labeled samples in a small dataset to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Peng Jiang , Juan Liu , Lang Wang , Zhihui Ynag , Hongyu Dong , Jing Feng

Semi-supervised learning addresses label scarcity and high annotation costs in medical image segmentation by exploiting the latent information in unlabeled data to enhance model performance. Traditional discriminative segmentation relies on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kaiwen Huang , Yi Zhou , Yizhe Zhang , Jingxiong Li , Tao Zhou

Weakly-supervised learning has become a popular technology in recent years. In this paper, we propose a novel medical image classification algorithm, called Weakly-Supervised Generative Adversarial Networks (WSGAN), which only uses a small…

Computer Vision and Pattern Recognition · Computer Science 2021-12-01 Jiawei Mao , Xuesong Yin , Yuanqi Chang , Qi Huang

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Weakly supervised semantic segmentation (WSSS) using only image-level labels can greatly reduce the annotation cost and therefore has attracted considerable research interest. However, its performance is still inferior to the fully…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Qi Yao , Xiaojin Gong

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

In the realm of digital pathology, multi-magnification Multiple Instance Learning (multi-mag MIL) has proven effective in leveraging the hierarchical structure of Whole Slide Images (WSIs) to reduce information loss and redundant data.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Yujian Liu , Ruoxuan Wu , Xinjie Shen , Zihuang Lu , Lingyu Liang , Haiyu Zhou , Shipu Xu , Shaoai Cai , Shidang Xu

Zero-shot learning (ZSL) aims to recognize unseen classes without visual instances. However, existing methods usually assume clean labels, overlooking real-world label noise and ambiguity, which degrades performance. To bridge this gap, we…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jiangnan Li , Linqing Huang , Xiaowen Yan , Min Gan , Wenpeng Lu , Jinfu Fan