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Avian Influenza breakouts cause millions of dollars in damage each year globally, especially in Asian countries such as China and South Korea. The impact magnitude of a breakout directly correlates to time required to fully understand the…

Quantitative Methods · Quantitative Biology 2018-02-27 Woo Yong Choi , Kyu Ye Song , Chan Woo Lee

Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between…

Applications · Statistics 2019-05-14 Vinny Davies , William T. Harvey , Richard Reeve , Dirk Husmeier

Viral zoonoses have emerged as the key drivers of recent pandemics. Human infection by zoonotic viruses are either spillover events -- isolated infections that fail to cause a widespread contagion -- or species jumps, where successful…

Populations and Evolution · Quantitative Biology 2018-01-25 Jaideep Dhanoa , Balaji Manicassamy , Ishanu Chattopadhyay

Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between…

We present a study of the worldwide spread of a pandemic influenza and its possible containment at a global level taking into account all available information on air travel. We studied a metapopulation stochastic epidemic model on a global…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alain-Jacques Valleron , Alessandro Vespignani

One Health issues, such as the spread of highly pathogenic avian influenza~(HPAI), present significant challenges at the human-animal-environmental interface. Recent H5N1 outbreaks underscore the need for comprehensive modeling efforts that…

Computational Engineering, Finance, and Science · Computer Science 2026-03-06 Abhijin Adiga , Ayush Chopra , Mandy L. Wilson , S. S. Ravi , Dawen Xie , Samarth Swarup , Bryan Lewis , Andrew Warren , John Barnes , Ramesh Raskar , Madhav V. Marathe

Highly pathogenic avian influenza (HPAI) has expanded its host range with recent detections in dairy cattle, raising critical concerns regarding within-herd persistence and cross-species spillover. This study develops a stochastic…

Dynamical Systems · Mathematics 2025-12-18 Parul Tiwari , Malavika Smitha , Hammed Olawale Fatoyinbo

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

Quantitative Methods · Quantitative Biology 2023-07-27 Tal Einav , Rong Ma

The Influenza type A virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Haemagglutinin (HA) gene of the virus has the potential to be a target for…

Quantitative Methods · Quantitative Biology 2021-02-16 Charalambos Chrysostomou , Harris Partaourides , Huseyin Seker

Accurate traffic forecasting is crucial for the development of Intelligent Transportation Systems (ITS), playing a pivotal role in modern urban traffic management. Traditional forecasting methods, however, struggle with the irregular…

Machine Learning · Computer Science 2024-08-28 Weijia Zhang , Le Zhang , Jindong Han , Hao Liu , Yanjie Fu , Jingbo Zhou , Yu Mei , Hui Xiong

While machine learning is rapidly being developed and deployed in health settings such as influenza prediction, there are critical challenges in using data from one environment in another due to variability in features; even within disease…

Machine Learning · Statistics 2020-03-10 Vishwali Mhasawade , Nabeel Abdur Rehman , Rumi Chunara

Epidemic prediction is a fundamental task for epidemic control and prevention. Many mechanistic models and deep learning models are built for this task. However, most mechanistic models have difficulty estimating the time/region-varying…

Computers and Society · Computer Science 2023-06-28 Qi Cao , Renhe Jiang , Chuang Yang , Zipei Fan , Xuan Song , Ryosuke Shibasaki

Honey bee colony losses threaten global pollination services, yet current monitoring systems treat each hive as an isolated unit, ignoring the spatial pathways through which diseases spread across apiaries. This paper introduces the…

Machine Learning · Computer Science 2026-05-19 Sungwoo Kang

The attack of novel avian influenza (H7N9) in east China caused a serious health crisis and public panic. In this paper, we empirically analyze the onset patterns of human cases of the novel avian influenza and observe several spatial and…

Physics and Society · Physics 2014-03-05 Ya-Nan Pan , Jing-Jing Lou , Xiao-Pu Han

Human seasonal influenza viruses evolve rapidly, enabling the virus population to evade immunity and re-infect previously infected individuals. Antigenic properties are largely determined by the surface glycoprotein hemagglutinin (HA) and…

Populations and Evolution · Quantitative Biology 2016-04-27 Richard A. Neher , Trevor Bedford , Rodney S. Daniels , Colin A. Russell , Boris I. Shraiman

This study presents a framework for predicting unsteady transonic wing pressure distributions, integrating an autoencoder architecture with graph convolutional networks and graph-based temporal layers to model time dependencies. The…

Machine Learning · Computer Science 2024-11-19 Gabriele Immordino , Andrea Vaiuso , Andrea Da Ronch , Marcello Righi

Since early 2024, highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.3.4.4b has spilled over from wild birds to dairy cattle in the United States (U.S.), spreading to more than 1000 herds and threatening both animal and public…

Populations and Evolution · Quantitative Biology 2026-03-12 You Chang , Jose L. Gonzales , Erik Rattenborg , Mart C. M. de Jong , Beate Conrady

This study presents a novel approach at the intersection of genomic analysis and artificial intelligence (AI) to predict viral mutations and assess the risks of future pandemics. Through comprehensive genomic analysis, genetic markers…

Other Quantitative Biology · Quantitative Biology 2023-09-29 Fadhil G. Al-Amran , Abbas M. Hezam , Salman Rawaf , Maitham G. Yousif

Traffic forecasting is significant for urban traffic management, intelligent route planning, and real-time flow monitoring. Recent advances in spatial-temporal models have markedly improved the modeling of intricate spatial-temporal…

Machine Learning · Computer Science 2025-09-03 Xinyu Ji , Chengcheng Yan , Jibiao Yuan , Fiefie Zhao

We propose an approach based on a combination of physical, chemical, and mathematical methods to identify and characterize virulent influenza A viruses (IAVs) through the analysis of the hemagglutinin protein. These methods include the…

Quantitative Methods · Quantitative Biology 2024-11-08 Meitner Cadena , Alejandro Yerovi