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Estimating population-level prevalence and transmission dynamics of wildlife pathogens can be challenging, partly because surveillance data is sparse, detection-driven, and unevenly sequenced. Using highly pathogenic avian influenza A/H5…

Populations and Evolution · Quantitative Biology 2026-01-16 Haley Stone , Jing Du , Yang Yang , Ashna Desai , Rebecca Dawson , Hao Xue , David Heslop , Matthew Scotch , Andreas Züfle , C. Raina MacIntyre , Flora Salim

Pathogen genome data offers valuable structure for spatial models, but its utility is limited by incomplete sequencing coverage. We propose a probabilistic framework for inferring genetic distances between unsequenced cases and known…

Genomics · Quantitative Biology 2025-09-10 Haley Stone , Jing Du , Hao Xue , Matthew Scotch , David Heslop , Andreas Züfle , Chandini Raina MacIntyre , Flora Salim

Accurate forecasting of avian disease outbreaks is critical for wildlife conservation and public health. This study presents a Transformer-based framework for predicting the disease risk at the terminal locations of migratory bird…

Machine Learning · Computer Science 2025-10-20 Dingya Feng , Dingyuan Xue

Among various spatio-temporal prediction tasks, epidemic forecasting plays a critical role in public health management. Recent studies have demonstrated the strong potential of spatio-temporal graph neural networks (STGNNs) in extracting…

Machine Learning · Computer Science 2025-12-30 Yufan Zheng , Wei Jiang , Tong Chen , Alexander Zhou , Nguyen Quoc Viet Hung , Choujun Zhan , Hongzhi Yin

H5N1 highly pathogenic avian influenza (HPAI) has been recently circulating in previously unseen patterns. As the underlying causes are uncertain, we need a better understanding of the drivers of virus circulation, as they underpin the…

Populations and Evolution · Quantitative Biology 2024-11-18 Anna Gamża , Sam Lycett , Aeron Sanchez , Rowland Kao

Community science observational datasets are useful in epidemiology and ecology for modeling species distributions, but the heterogeneous nature of the data presents significant challenges for standardization, data quality assurance and…

Populations and Evolution · Quantitative Biology 2025-12-10 Richard Littauer , Kris Bubendorfer

Infectious diseases on farms pose both public and animal health risks, so understanding how they spread between farms is crucial for developing disease control strategies to prevent future outbreaks. We develop novel Bayesian nonparametric…

Applications · Statistics 2021-08-24 R. G. Seymour , T. Kypraios , P. D. O'Neill , T. J. Hagenaars

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

Epidemic forecasting is the key to effective control of epidemic transmission and helps the world mitigate the crisis that threatens public health. To better understand the transmission and evolution of epidemics, we propose EpiGNN, a graph…

Quantitative Methods · Quantitative Biology 2022-08-25 Feng Xie , Zhong Zhang , Liang Li , Bin Zhou , Yusong Tan

The Influenza virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Hemagglutinin (HA) gene of the virus can be a target for antiviral drug development…

Quantitative Methods · Quantitative Biology 2021-08-11 Charalambos Chrysostomou , Floris Alexandrou , Mihalis A. Nicolaou , Huseyin Seker

We present an analysis of an avian flu model that yields insight into the role of different transmission routes in the recurrence of avian influenza epidemics. Recent modelling work on avian influenza in wild bird populations takes into…

Populations and Evolution · Quantitative Biology 2017-03-16 May Anne E. Mata , Priscilla E. Greenwood , Rebecca C. Tyson

Global mobility flow data are at the heart of spatial epidemiological models used to predict infectious disease behavior but this wealth of data on human mobility has been largely neglected by reconstructions of pathogen evolutionary…

Heterogeneous data are commonly adopted as the inputs for some models that predict the future trends of some observations. Existing predictive models typically ignore the inconsistencies and imperfections in heterogeneous data while also…

Machine Learning · Computer Science 2022-05-10 Zhengjing Ma , Gang Mei , Salvatore Cuomo , Francesco Piccialli

Forecasting infectious disease incidence can provide important information to guide public health planning, yet is difficult because epidemic dynamics are complex. Current mechanistic and statistical approaches often struggle to capture…

Machine Learning · Computer Science 2026-04-29 Joseph Lemaitre , Justin Lessler

Accurate air quality prediction is becoming increasingly important in the environmental field. To address issues such as low prediction accuracy and slow real-time updates in existing models, which lead to lagging prediction results, we…

Machine Learning · Computer Science 2025-08-27 Dan Wang , Feng Jiang , Zhanquan Wang

Graph-structured data and their related algorithms have attracted significant attention in many fields, such as influenza prediction in public health. However, the variable influenza seasonality, occasional pandemics, and domain knowledge…

Artificial Intelligence · Computer Science 2021-02-17 Jie Zhang , Pengfei Zhou , Hongyan Wu

Modelling epidemic events such as COVID-19 cases in both time and space dimensions is an important but challenging task. Building on in-depth review and assessment of two popular graph neural network (GNN)-based regional epidemic…

Computation · Statistics 2025-11-20 Xiangxin Kong , Hang Wang , Yutong Li , Yanghao Chen , Zudi Lu

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

The seasonal human influenza virus undergoes rapid evolution, leading to significant changes in circulating viral strains from year to year. These changes are typically driven by adaptive mutations, particularly in the antigenic epitopes,…

Populations and Evolution · Quantitative Biology 2024-11-28 Matthijs Meijers , Denis Ruchnewitz , Jan Eberhardt , Malancha Karmakar , Marta Łuksza , Michael Lässig

The global spread of avian influenza A viruses in domestic birds is causing dramatic economic and social losses. Various mechanistic models have been developed in an attempt to better understand avian influenza transmission and to evaluate…

Quantitative Methods · Quantitative Biology 2023-03-02 Sébastien Lambert , Billy Bauzile , Amélie Mugnier , Benoit Durand , Timothée Vergne , Mathilde C Paul
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