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How an individual's unique brain connectivity determines that individual's cognition, behavior, and risk for pathology is a fundamental question in basic and clinical neuroscience. In seeking answers, many have turned to machine learning,…

Neurons and Cognition · Quantitative Biology 2023-12-08 Maxwell A. Bertolero , Dustin Moraczewski , Adam Thomas , Danielle S. Bassett

Tractography plays a pivotal role in the non-invasive reconstruction of white matter fiber pathways, providing vital information on brain connectivity and supporting precise neurosurgical planning. Although traditional methods relied mainly…

Machine Learning · Computer Science 2026-01-21 Ankita Joshi , Ashutosh Sharma , Anoushkrit Goel , Ranjeet Ranjan Jha , Chirag Ahuja , Arnav Bhavsar , Aditya Nigam

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Deep learning has emerged as a promising approach for learning the nonlinear mapping between diffusion-weighted MR images and tissue parameters, which enables automatic and deep understanding of the brain microstructures. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenxin Fan , Jian Cheng , Qiyuan Tian , Ruoyou Wu , Juan Zou , Zan Chen , Shanshan Wang

Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

In this work, we study the extent to which structural connectomes and topological derivative measures are unique to individual changes within human brains. To do so, we classify structural connectome pairs from two large longitudinal…

Neurons and Cognition · Quantitative Biology 2017-02-01 Dmitry Petrov , Boris Gutman , Alexander Ivanov , Joshua Faskowitz , Neda Jahanshad , Mikhail Belyaev , Paul Thompson

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

Brain connectomes, representing neural connectivity as graphs, are crucial for understanding brain organization but costly and time-consuming to acquire, motivating generative approaches. Recent advances in graph generative modeling offer a…

Machine Learning · Computer Science 2025-08-14 Yitong Luo , Islem Rekik

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

Machine Learning · Computer Science 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…

Image and Video Processing · Electrical Eng. & Systems 2019-11-20 Mehdi Amian , Mohammadreza Soltaninejad

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

Neurons and Cognition · Quantitative Biology 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

Applying network science approaches to investigate the functions and anatomy of the human brain is prevalent in modern medical imaging analysis. Due to the complex network topology, for an individual brain, mining a discriminative network…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Wen Zhang , Liang Zhan , Paul Thompson , Yalin Wang

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

Predicting future human motion is critical for intelligent robots to interact with humans in the real world, and human motion has the nature of multi-granularity. However, most of the existing work either implicitly modeled…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Xiaoli Liu , Jianqin Yin

Mapping the functional connectome has the potential to uncover key insights into brain organisation. However, existing workflows for functional connectomics are limited in their adaptability to new data, and principled workflow design is a…

Neurons and Cognition · Quantitative Biology 2022-06-02 Rastko Ciric , Armin W. Thomas , Oscar Esteban , Russell A. Poldrack

One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open…

Neurons and Cognition · Quantitative Biology 2018-02-22 Enrico Amico , Joaquín Goñi
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