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A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

Machine Learning · Computer Science 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Accurate estimation of plant skeletal structures (e.g., branching structures) from images is essential for smart agriculture and plant science. Unlike human skeletons with fixed topology, plant skeleton estimation presents a unique…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xinpeng Liu , Hiroaki Santo , Yosuke Toda , Fumio Okura

Machine learning in atomistic materials science has grown to become a powerful tool, with most approaches focusing on atomic arrangements, typically decomposed into local atomic environments. This approach, while well-suited for…

Materials Science · Physics 2025-03-12 Austin Zadoks , Antimo Marrazzo , Nicola Marzari

We introduce a new method for non-rigid registration of 3D human shapes. Our proposed pipeline builds upon a given parametric model of the human, and makes use of the functional map representation for encoding and inferring shape maps…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Riccardo Marin , Simone Melzi , Emanuele Rodolà , Umberto Castellani

Dense indoor scene modeling from 2D images has been bottlenecked due to the absence of depth information and cluttered occlusions. We present an automatic indoor scene modeling approach using deep features from neural networks. Given a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Yinyu Nie , Shihui Guo , Jian Chang , Xiaoguang Han , Jiahui Huang , Shi-Min Hu , Jian Jun Zhang

Learning structures of 3D shapes is a fundamental problem in the field of computer graphics and geometry processing. We present a simple yet interpretable unsupervised method for learning a new structural representation in the form of 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-03-27 Nenglun Chen , Lingjie Liu , Zhiming Cui , Runnan Chen , Duygu Ceylan , Changhe Tu , Wenping Wang

We propose a novel framework to automatically learn to aggregate and transform photometric measurements from multiple unstructured views into spatially distinctive and view-invariant low-level features, which are subsequently fed to a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Xiang Feng , Kaizhang Kang , Fan Pei , Huakeng Ding , Jinjiang You , Ping Tan , Kun Zhou , Hongzhi Wu

We propose LeafFit, a pipeline that converts 3D Gaussian Splatting (3DGS) of individual plants into editable, instanced mesh assets. While 3DGS faithfully captures complex foliage, its high memory footprint and lack of mesh topology make it…

Graphics · Computer Science 2026-02-13 Chang Luo , Nobuyuki Umetani

Geometric trees are characterized by their tree-structured layout and spatially constrained nodes and edges, which significantly impacts their topological attributes. This inherent hierarchical structure plays a crucial role in domains such…

Machine Learning · Computer Science 2024-08-19 Zheng Zhang , Allen Zhang , Ruth Nelson , Giorgio Ascoli , Liang Zhao

Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Neel Dey , Benjamin Billot , Hallee E. Wong , Clinton J. Wang , Mengwei Ren , P. Ellen Grant , Adrian V. Dalca , Polina Golland

We propose to use a simulation driven inverse inference approach to model the dynamics of tree branches under manipulation. Learning branch dynamics and gaining the ability to manipulate deformable vegetation can help with occlusion-prone…

Robotics · Computer Science 2023-12-21 Jayadeep Jacob , Tirthankar Bandyopadhyay , Jason Williams , Paulo Borges , Fabio Ramos

We propose an unsupervised method for parsing large 3D scans of real-world scenes with easily-interpretable shapes. This work aims to provide a practical tool for analyzing 3D scenes in the context of aerial surveying and mapping, without…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Romain Loiseau , Elliot Vincent , Mathieu Aubry , Loic Landrieu

We propose and study a multi-scale approach to vector quantization. We develop an algorithm, dubbed reconstruction trees, inspired by decision trees. Here the objective is parsimonious reconstruction of unsupervised data, rather than…

Machine Learning · Computer Science 2019-09-05 Enrico Cecini , Ernesto De Vito , Lorenzo Rosasco

An in-vitro cell culture system is used for biological discoveries and hypothesis-driven research on a particular cell type to understand mechanistic or test pharmaceutical drugs. Conventional in-vitro cultures have been applied to primary…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Alireza Ranjbaran , Azadeh Nazemi

When interacting in a three dimensional world, humans must estimate 3D structure from visual inputs projected down to two dimensional retinal images. It has been shown that humans use the persistence of object shape over motion-induced…

Neurons and Cognition · Quantitative Biology 2023-04-03 Marissa Connor , Bruno Olshausen , Christopher Rozell

We introduce a novel learning-based method for encoding and manipulating 3D surface meshes. Our method is specifically designed to create an interpretable embedding space for deformable shape collections. Unlike previous 3D mesh…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Sara Hahner , Souhaib Attaiki , Jochen Garcke , Maks Ovsjanikov

Machine learning methods have shown promise in predicting molecular properties, and given sufficient training data machine learning approaches can enable rapid high-throughput virtual screening of large libraries of compounds. Graph-based…

Automated analysis of imaged phenotypes enables fast and reproducible quantification of biologically relevant features. Despite recent developments, recordings of complex, networked structures, such as: leaf venation patterns, cytoskeletal…

Quantitative Methods · Quantitative Biology 2017-06-01 David Breuer , Zoran Nikoloski

Quantification of physiological changes in plants can capture different drought mechanisms and assist in selection of tolerant varieties in a high throughput manner. In this context, an accurate 3D model of plant canopy provides a reliable…

Computer Vision and Pattern Recognition · Computer Science 2017-10-19 Siddharth Srivastava , Swati Bhugra , Brejesh Lall , Santanu Chaudhury

Automating leaf manipulation in agricultural settings faces significant challenges, including the variability of plant morphologies and deformable leaves. We propose a novel hybrid geometric-neural approach for autonomous leaf grasping that…

Robotics · Computer Science 2025-05-20 Srecharan Selvam
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