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Causal inference plays a crucial role in scientific research across multiple disciplines. Estimating causal effects, particularly the average treatment effect (ATE), from observational data has garnered significant attention. However,…

Cryptography and Security · Computer Science 2025-12-17 Quan Yuan , Xiaochen Li , Linkang Du , Min Chen , Mingyang Sun , Yunjun Gao , Shibo He , Jiming Chen , Zhikun Zhang

Patient privacy is a major barrier to healthcare AI. For confidentiality reasons, most patient data remains in silo in separate hospitals, preventing the design of data-driven healthcare AI systems that need large volumes of patient data to…

Machine Learning · Computer Science 2023-10-11 Tatsuki Koga , Kamalika Chaudhuri , David Page

Estimating causal effects from observational data is essential in fields such as medicine, economics and social sciences, where privacy concerns are paramount. We propose a general, model-agnostic framework for differentially private…

Machine Learning · Computer Science 2026-02-02 Christian Janos Lebeda , Mathieu Even , Aurélien Bellet , Julie Josse

Constructing confidence intervals (CIs) for the average treatment effect (ATE) from patient records is crucial to assess the effectiveness and safety of drugs. However, patient records typically come from different hospitals, thus raising…

Machine Learning · Computer Science 2025-10-16 Yuxin Wang , Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Hess , Stefan Feuerriegel

Patient data is widely used to estimate heterogeneous treatment effects and thus understand the effectiveness and safety of drugs. Yet, patient data includes highly sensitive information that must be kept private. In this work, we aim to…

Machine Learning · Computer Science 2025-03-06 Maresa Schröder , Valentyn Melnychuk , Stefan Feuerriegel

Estimating heterogeneous treatment effects in domains such as healthcare or social science often involves sensitive data where protecting privacy is important. We introduce a general meta-algorithm for estimating conditional average…

Machine Learning · Statistics 2022-02-23 Fengshi Niu , Harsha Nori , Brian Quistorff , Rich Caruana , Donald Ngwe , Aadharsh Kannan

Experiment design has a rich history dating back over a century and has found many critical applications across various fields since then. The use and collection of users' data in experiments often involve sensitive personal information, so…

Cryptography and Security · Computer Science 2023-11-09 Wei-Ning Chen , Graham Cormode , Akash Bharadwaj , Peter Romov , Ayfer Özgür

The estimation of conditional average treatment effects (CATEs) is an important topic in many scientific fields. CATEs can be estimated with high accuracy if data distributed across multiple parties are centralized. However, it is difficult…

Methodology · Statistics 2025-07-28 Yuji Kawamata , Ryoki Motai , Yukihiko Okada , Akira Imakura , Tetsuya Sakurai

Differential Privacy (DP) is a mathematical framework for releasing information with formal privacy guarantees. While numerous DP procedures have been developed for statistical analysis and machine learning, valid statistical inference…

Methodology · Statistics 2025-06-27 Ruyu Zhou , Fang Liu

Applying machine learning (ML) to sensitive domains requires privacy protection of the underlying training data through formal privacy frameworks, such as differential privacy (DP). Yet, usually, the privacy of the training data comes at…

Machine Learning · Computer Science 2022-11-09 Franziska Boenisch , Christopher Mühl , Roy Rinberg , Jannis Ihrig , Adam Dziedzic

The randomized controlled trial (RCT) is the gold standard for estimating the average treatment effect (ATE) of a medical intervention but requires 100s-1000s of subjects, making it expensive and difficult to implement. While a cross-over…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Sayeri Lala , Niraj K. Jha

The Average Treatment Effect (ATE) is a global measure of the effectiveness of an experimental treatment intervention. Classical methods of its estimation either ignore relevant covariates or do not fully exploit them. Moreover, past work…

Methodology · Statistics 2013-11-05 Emil Pitkin , Richard Berk , Lawrence Brown , Andreas Buja , Ed George , Kai Zhang , Linda Zhao

The Private Aggregation of Teacher Ensembles (PATE) is an important private machine learning framework. It combines multiple learning models used as teachers for a student model that learns to predict an output chosen by noisy voting among…

Machine Learning · Computer Science 2021-09-20 Cuong Tran , My H. Dinh , Kyle Beiter , Ferdinando Fioretto

In the social and health sciences, researchers often make causal inferences using sensitive variables. These researchers, as well as the data holders themselves, may be ethically and perhaps legally obligated to protect the confidentiality…

Methodology · Statistics 2024-08-28 Sharmistha Guha , Jerome P. Reiter

Differential privacy is a restriction on data processing algorithms that provides strong confidentiality guarantees for individual records in the data. However, research on proper statistical inference, that is, research on properly…

Cryptography and Security · Computer Science 2021-07-06 Joerg Drechsler , Ira Globus-Harris , Audra McMillan , Jayshree Sarathy , Adam Smith

Auditing mechanisms for differential privacy use probabilistic means to empirically estimate the privacy level of an algorithm. For private machine learning, existing auditing mechanisms are tight: the empirical privacy estimate (nearly)…

Differential privacy is the leading mathematical framework for privacy protection, providing a probabilistic guarantee that safeguards individuals' private information when publishing statistics from a dataset. This guarantee is achieved by…

Methodology · Statistics 2025-08-19 Yuki Ohnishi , Jordan Awan

Confidence intervals for the population mean of normally distributed data are some of the most standard statistical outputs one might want from a database. In this work we give practical differentially private algorithms for this task. We…

Methodology · Statistics 2020-01-09 Wenxin Du , Canyon Foot , Monica Moniot , Andrew Bray , Adam Groce

Individual treatment effect (ITE) is often regarded as the ideal target of inference in causal analyses and has been the focus of several recent studies. In this paper, we describe the intrinsic limits regarding what can be learned…

Methodology · Statistics 2025-06-10 Zhehao Zhang , Thomas S. Richardson

Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is…

Machine Learning · Computer Science 2024-10-15 Jonas Schweisthal , Dennis Frauen , Maresa Schröder , Konstantin Hess , Niki Kilbertus , Stefan Feuerriegel
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