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Protein language models (pLMs) have demonstrated success at generating functional proteins across vast sequence spaces but lack the ability to design high-fitness variants on demand. Here, we iteratively guide pLMs toward user-defined…
Recent work using auxiliary prediction task classifiers to investigate the properties of LSTM representations has begun to shed light on why pretrained representations, like ELMo (Peters et al., 2018) and CoVe (McCann et al., 2017), are so…
This work introduces an approach to assessing phrase break in ESL learners' speech with pre-trained language models (PLMs). Different with traditional methods, this proposal converts speech to token sequences, and then leverages the power…
Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…
Pre-trained Language Models (PLMs) have been widely used in various natural language processing (NLP) tasks, owing to their powerful text representations trained on large-scale corpora. In this paper, we propose a new PLM called PERT for…
Neural Machine Translation (NMT) has become a significant technology in natural language processing through extensive research and development. However, the deficiency of high-quality bilingual language pair data still poses a major…
Vision-language models (VLMs) have made substantial progress across a wide range of visual question answering benchmarks, spanning visual reasoning, document understanding, and multimodal dialogue. These improvements are evident in a wide…
Proteins are complex biomolecules that play a central role in various biological processes, making them critical targets for breakthroughs in molecular biology, medical research, and drug discovery. Deciphering their intricate, hierarchical…
Recently, decomposing complex problems into simple subtasks--a crucial part of human-like natural planning--to solve the given problem has significantly boosted the performance of large language models (LLMs). However, leveraging such…
Pre-trained language models (PrLM) has been shown powerful in enhancing a broad range of downstream tasks including various dialogue related ones. However, PrLMs are usually trained on general plain text with common language model (LM)…
Simile interpretation is a crucial task in natural language processing. Nowadays, pre-trained language models (PLMs) have achieved state-of-the-art performance on many tasks. However, it remains under-explored whether PLMs can interpret…
Recently, Language Models (LMs) instruction-tuned on multiple tasks, also known as multitask-prompted fine-tuning (MT), have shown the capability to generalize to unseen tasks. Previous work has shown that scaling the number of training…
Representation learning for proteins has primarily focused on the global understanding of protein sequences regardless of their length. However, shorter proteins (known as peptides) take on distinct structures and functions compared to…
Keyphrase Generation (KPG) is a longstanding task in NLP with widespread applications. The advent of sequence-to-sequence (seq2seq) pre-trained language models (PLMs) has ushered in a transformative era for KPG, yielding promising…
The recent prevalence of pretrained language models (PLMs) has dramatically shifted the paradigm of semantic parsing, where the mapping from natural language utterances to structured logical forms is now formulated as a Seq2Seq task.…
Recent Pre-trained Language Models (PLMs) usually only provide users with the inference APIs, namely the emerging Model-as-a-Service (MaaS) setting. To adapt MaaS PLMs to downstream tasks without accessing their parameters and gradients,…
Identification of protein-protein interactions (PPIs) helps derive cellular mechanistic understanding, particularly in the context of complex conditions such as neurodegenerative disorders, metabolic syndromes, and cancer. Large Language…
Parameter-efficient (PE) methods (like Prompts or Adapters) for adapting pre-trained language models (PLM) to downstream tasks have been popular recently. However, hindrances still prevent these methods from reaching their full potential.…
Masked language modeling (MLM) plays a key role in pretraining large language models. But the MLM objective is often dominated by high-frequency words that are sub-optimal for learning factual knowledge. In this work, we propose an approach…
The advance of Artificial Intelligence (AI) is continuously reshaping the future 6G wireless communications. Particularly, the development of Large Language Models (LLMs) offers a promising approach to effectively improve the performance…