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Coronary angioplasty with stent implantation is the most frequently used interventional treatment for coronary artery disease. However, reocclusion within the stent, referred to as in-stent restenosis, occurs in up to 10% of lesions. It is…

Computational Engineering, Finance, and Science · Computer Science 2025-02-19 Janina C. Datz , Ivo Steinbrecher , Christoph Meier , Nora Hagmeyer , Leif-Christopher Engel , Alexander Popp , Martin R. Pfaller , Heribert Schunkert , Wolfgang A. Wall

In this study, finite element analysis is used to simulate the surgical deployment procedure of a bifurcated stent-graft on a real patient's arterial geometry. The stent-graft is modeled using realistic constitutive properties for both the…

As experts continue to debate the optimal surgery practice for coronary disease - percutaneous coronary intervention (PCI) or coronary aortic bypass graft (CABG) - computational tools may provide a quantitative assessment of each option.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-09 Boyi Yang , Marina Piccinelli , Gaetano Esposito , Tianli Han , Yasir Bouchi , Bill Gogas , Don Giddens , Habib Samady , Alessandro Veneziani

This work reports on a study to develop a patient-specific finite element model of the Transcatheter Aortic Valve Implantation procedure, using a model of a balloon-expandable percutaneous prosthetic aortic valve as a framework for the…

Medical Physics · Physics 2019-10-02 Mehdi Shirzadi , B. Daya Reddy , Harish Appa

Cerebral vasospasm, a prolonged constriction of cerebral arteries, is the first cause of morbidity and mortality for patients who survive hospitalisation after aneurysmal subarachnoid haemorrhage. The recent finding that stent-retrievers…

Computational Engineering, Finance, and Science · Computer Science 2024-09-02 Giulia Pederzani , Andrii Grytsan , Alfons G. Hoekstra , Anne M. Robertson , Paul N. Watton

Coronary stent designs have undergone significant transformations in geometry, materials, and drug elution coatings, contributing to the continuous improvement of stenting success over recent decades. However, the increasing use of…

Medical Physics · Physics 2023-12-25 Ankush Kapoor , Nigel Jepson , Neil W. Bressloff , Poay Huan Loh , Tapabrata Ray , Susann Beier

Balloon dilation catheters are often used to quantify the physiological state of peristaltic activity in tubular organs and comment on their ability to propel fluid which is important for healthy human function. To fully understand this…

From the perspective of coronary heart disease, the development of stents has come significantly far in reducing the associated mortality rate, drug-eluting stents being the epitome of innovative and effective solutions. Within this work,…

Computational Engineering, Finance, and Science · Computer Science 2020-12-15 Kiran Manjunatha , Marek Behr , Felix Vogt , Stefanie Reese

Development of in silico models are intrinsic in understanding disease progression in soft biological tissues. Within this work, we propose a fully-coupled Lagrangian finite element framework which replicates the process of in-stent…

Computational Engineering, Finance, and Science · Computer Science 2022-04-08 Kiran Manjunatha , Marek Behr , Felix Vogt , Stefanie Reese

The aim of this work was to simulate the behaviour of hip prostheses under mechanical shocks. When hip joint is replaced by prosthesis, during the swing phase of the leg, a microseparation between the prosthetic head and the cup could…

Medical Physics · Physics 2012-03-29 Juliana Uribe , Jérôme Hausselle , Jean Geringer

The rapid expansion of TAVR to younger, low-risk patients raises concerns regarding device durability. Necessarily, extended stent lifetime will become more critical for new generation devices. In vitro methods commonly used for TAVR stent…

Computational Engineering, Finance, and Science · Computer Science 2023-09-15 Kyle Baylous , Ryan Helbock , Brandon Kovarovic , Salwa Anam , Marvin Slepian , Danny Bluestein

Stenting is among the most common transcatheter interventions for congenital heart disease (CHD). Patient-specific computational fluid dynamics (CFD) simulations can predict hemodynamic outcomes of intervention scenarios but require…

Computational Engineering, Finance, and Science · Computer Science 2026-05-22 Bohan J. Li , Nicholas C. Dorn , Andras Lasso , Matthew A. Jolley , Jeffrey A. Feinstein , Doug L. James , Alison L. Marsden

A unified Smoothed Particle Hydrodynamics (SPH) simulation framework for coronary stent implantation is developed, which unifies weakly compressible hemodynamics, Neo-Hookean solids, and stent-artery contacts, based on a multi-resolution…

Fluid Dynamics · Physics 2025-11-13 Jinlei Zhou , Sukang Peng , Yongchuan Yu , Dong Wu , Xiangyu Hu

BACKGROUND Careful evaluation of the risk of stent under-expansions before the intervention will aid treatment planning, including the application of a pre-stent plaque modification strategy. OBJECTIVES It remains challenging to achieve a…

Stent intervention is a recommended therapy to reduce the pressure gradient and restore blood flow for patients with coarctation of the aorta (CoA). In this work, we developed a framework for personalized stent intervention in CoA using in…

Medical Physics · Physics 2022-10-12 Dandan Ma , Yong Wang , Mueed Azhar , Ansgar Adler , Michael Steinmetz , Martin Uecker

Simulation of arterial stenting procedures prior to intervention allows for appropriate device selection as well as highlights potential complications. To this end, we present a framework for facilitating virtual aortic stenting from a…

Computer Vision and Pattern Recognition · Computer Science 2011-03-10 Jan Egger , Bernd Freisleben , Randolph Setser , Rahul Renapuraar , Christina Biermann , Thomas O'Donnell

Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…

Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…

Computational Engineering, Finance, and Science · Computer Science 2023-01-23 Beatrice Bisighini , Miquel Aguirre , Marco Evangelos Biancolini , Federica Trovalusci , David Perrin , Stephane Avril , Baptiste Pierrat

Deformation properties of venous stents based on braided design, chevron design, Z design, and diamond design are compared using in vitro experiments coupled with analytical and finite element modelling. Their suitability for deployment in…

Medical Physics · Physics 2021-02-23 Masoud Hejazi , Farrokh Sassani , Joel Gagnon , York Hsiang , Srikantha Phani

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi
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