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With the rapid expansion of unstructured clinical texts in electronic health records (EHRs), clinical named entity recognition (NER) has become a crucial technique for extracting medical information. However, traditional supervised models…

Computation and Language · Computer Science 2026-03-31 Xinli Tao , Xin Dong , Xuezhong Zhou

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir

The development of Electronic Health Records summarization systems has revolutionized patient data management. Previous research advanced this field by adapting Large Language Models for clinical tasks, using diverse datasets to generate…

Computation and Language · Computer Science 2024-10-15 Ruvarashe Madzime , Clement Nyirenda

The use of Large Language Models (LLMs) to support patients in addressing medical questions is becoming increasingly prevalent. However, most of the measures currently used to evaluate the performance of these models in this context only…

Human-Computer Interaction · Computer Science 2026-04-22 Abu Noman Md Sakib , Md. Main Oddin Chisty , Zijie Zhang

Objective: Large language models (LLMs) are increasingly applied in biomedical settings, and existing benchmark datasets have played an important role in supporting model development and evaluation. However, these benchmarks often have…

Computation and Language · Computer Science 2026-01-21 Kriti Bhattarai , Vipina K. Keloth , Donald Wright , Andrew Loza , Yang Ren , Hua Xu

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Despite the growing clinical adoption of large language models (LLMs), current approaches heavily rely on single model architectures. To overcome risks of obsolescence and rigid dependence on single model systems, we present a novel…

Artificial Intelligence · Computer Science 2025-06-24 Amit Kumthekar , Zion Tilley , Henry Duong , Bhargav Patel , Michael Magnoli , Ahmed Omar , Ahmed Nasser , Chaitanya Gharpure , Yevgen Reztzov

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Conversational AI systems have emerged as key enablers of human-like interactions across diverse sectors. Nevertheless, the balance between linguistic nuance and factual accuracy has proven elusive. In this paper, we first introduce…

Computation and Language · Computer Science 2024-06-18 Ahtsham Zafar , Venkatesh Balavadhani Parthasarathy , Chan Le Van , Saad Shahid , Aafaq Iqbal khan , Arsalan Shahid

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

Clinical text structuring is a critical and fundamental task for clinical research. Traditional methods such as taskspecific end-to-end models and pipeline models usually suffer from the lack of dataset and error propagation. In this paper,…

Computation and Language · Computer Science 2019-10-23 Jiahui Qiu , Yangming Zhou , Zhiyuan Ma , Tong Ruan , Jinlin Liu , Jing Sun

Agents represent one of the most emerging applications of Large Language Models (LLMs) and Generative AI, with their effectiveness hinging on multimodal capabilities to navigate complex user environments. Conversational Health Agents…

Computation and Language · Computer Science 2024-05-09 Mahyar Abbasian , Iman Azimi , Mohammad Feli , Amir M. Rahmani , Ramesh Jain

We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical…

Computation and Language · Computer Science 2024-10-18 Cheng Qian , Xianglong Shi , Shanshan Yao , Yichen Liu , Fengming Zhou , Zishu Zhang , Junaid Akram , Ali Braytee , Ali Anaissi

Large Language Model (LLM)-based Collective Intelligence (CI) presents a promising approach to overcoming the data wall and continuously boosting the capabilities of LLM agents. However, there is currently no dedicated arena for evolving…

Artificial Intelligence · Computer Science 2026-03-18 Peigen Liu , Rui Ding , Yuren Mao , Ziyan Jiang , Yuxiang Ye , Yunjun Gao , Ying Zhang , Renjie Sun , Longbin Lai , Zhengping Qian

Real-world clinical text-to-SQL requires reasoning over heterogeneous EHR tables, temporal windows, and patient-similarity cohorts to produce executable queries. We introduce CLINSQL, a benchmark of 633 expert-annotated tasks on MIMIC-IV…

Computation and Language · Computer Science 2026-01-16 Yifei Shen , Yilun Zhao , Justice Ou , Tinglin Huang , Arman Cohan

The exponential growth of AI in science necessitates efficient and scalable solutions for retrieving and preserving research information. Here, we present a tool for the development of a customized question-answer (QA) dataset, called…

Information Retrieval · Computer Science 2025-02-25 Qiming Liu , Zhongzheng Niu , Siting Liu , Mao Tian

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang