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Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large Language Models (LLMs) have demonstrated remarkable performance on various medical question-answering (QA) benchmarks, including standardized medical exams. However, correct answers alone do not ensure correct logic, and models may…

Computation and Language · Computer Science 2025-06-02 Yuexing Hao , Kumail Alhamoud , Hyewon Jeong , Haoran Zhang , Isha Puri , Philip Torr , Mike Schaekermann , Ariel D. Stern , Marzyeh Ghassemi

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

We propose a novel methodology to generate domain-specific large-scale question answering (QA) datasets by re-purposing existing annotations for other NLP tasks. We demonstrate an instance of this methodology in generating a large-scale QA…

Computation and Language · Computer Science 2018-09-05 Anusri Pampari , Preethi Raghavan , Jennifer Liang , Jian Peng

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…

Computation and Language · Computer Science 2020-11-02 Claudia Schulz , Josh Levy-Kramer , Camille Van Assel , Miklos Kepes , Nils Hammerla

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

This research examines the use of Reinforcement Learning from AI Feedback (RLAIF) techniques to improve healthcare dialogue models, with the aim of tackling the challenges of preference-aligned data annotation while reducing the reliance on…

Computation and Language · Computer Science 2024-10-08 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

Timing of clinical events is central to characterization of patient trajectories, enabling analyses such as process tracing, forecasting, and causal reasoning. However, structured electronic health records capture few data elements critical…

Computation and Language · Computer Science 2025-04-18 Jing Wang , Jeremy C Weiss

Conversational question answering systems often rely on semantic parsing to enable interactive information retrieval, which involves the generation of structured database queries from a natural language input. For information-seeking…

Computation and Language · Computer Science 2024-01-04 Phillip Schneider , Manuel Klettner , Kristiina Jokinen , Elena Simperl , Florian Matthes

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Thematic analysis (TA) is widely used in health research to extract patterns from patient interviews, yet manual TA faces challenges in scalability and reproducibility. LLM-based automation can help, but existing approaches produce…

Question Answering (QA) in clinical notes has gained a lot of attention in the past few years. Existing machine reading comprehension approaches in clinical domain can only handle questions about a single block of clinical texts and fail to…

Computation and Language · Computer Science 2022-07-25 Ping Wang , Tian Shi , Khushbu Agarwal , Sutanay Choudhury , Chandan K. Reddy

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Millions of people take surveys every day, from market polls and academic studies to medical questionnaires and customer feedback forms. These datasets capture valuable insights, but their scale and structure present a unique challenge for…

Artificial Intelligence · Computer Science 2025-10-31 Duc-Hai Nguyen , Vijayakumar Nanjappan , Barry O'Sullivan , Hoang D. Nguyen

Patients are increasingly turning to large language models (LLMs) with medical questions that are complex and difficult to articulate clearly. However, LLMs are sensitive to prompt phrasings and can be influenced by the way questions are…

Computation and Language · Computer Science 2026-04-08 Hye Sun Yun , Geetika Kapoor , Michael Mackert , Ramez Kouzy , Wei Xu , Junyi Jessy Li , Byron C. Wallace

Visual question answering (VQA) in medical imaging aims to support clinical diagnosis by automatically interpreting complex imaging data in response to natural language queries. Existing studies typically rely on distinct visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuanhe Tian , Chen Su , Junwen Duan , Yan Song

When applied directly in an end-to-end manner to medical follow-up tasks, Large Language Models (LLMs) often suffer from uncontrolled dialog flow and inaccurate information extraction due to the complexity of follow-up forms. To address…

Computation and Language · Computer Science 2025-12-23 Jinyan Liu , Zikang Chen , Qinchuan Wang , Tan Xie , Heming Zheng , Xudong Lv

Background: Clinical trials rely on transparent inclusion criteria to ensure generalizability. In contrast, benchmarks validating health-related large language models (LLMs) rarely characterize the "patient" or "query" populations they…

Artificial Intelligence · Computer Science 2026-04-17 Alvin Rajkomar , Pavan Sudarshan , Angela Lai , Lily Peng

Generative Artificial Intelligence is set to revolutionize healthcare delivery by transforming traditional patient care into a more personalized, efficient, and proactive process. Chatbots, serving as interactive conversational models, will…

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