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Conversational Health Agents (CHAs) are interactive systems that provide healthcare services, such as assistance and diagnosis. Current CHAs, especially those utilizing Large Language Models (LLMs), primarily focus on conversation aspects.…

Computation and Language · Computer Science 2024-09-26 Mahyar Abbasian , Iman Azimi , Amir M. Rahmani , Ramesh Jain

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Despite the impressive performance of LLM-powered agents, their adoption for Electronic Health Record (EHR) data access remains limited by the absence of benchmarks that adequately capture real-world clinical data access flows. In practice,…

Artificial Intelligence · Computer Science 2026-03-03 Gyubok Lee , Woosog Chay , Heeyoung Kwak , Yeong Hwa Kim , Haanju Yoo , Oksoon Jeong , Meong Hi Son , Edward Choi

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

Human-Computer Interaction · Computer Science 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj

Clinical calculators are widely used, and large language models (LLMs) make it possible to engage them using natural language. We demonstrate a purpose-built chatbot that leverages software implementations of verifiable clinical calculators…

Quantitative Methods · Quantitative Biology 2025-03-25 Niranjan Kumar , Farid Seifi , Marisa Conte , Allen Flynn

Evaluating multi-paragraph clinical question answering (QA) systems is resource-intensive and challenging: accurate judgments require medical expertise and achieving consistent human judgments over multi-paragraph text is difficult. We…

Computation and Language · Computer Science 2026-04-06 Federica Bologna , Tiffany Pan , Matthew Wilkens , Yue Guo , Lucy Lu Wang

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

Large language models (LLMs) exhibit strong medical knowledge and can generate factually accurate responses. However, existing models often fail to account for individual patient contexts, producing answers that are clinically correct yet…

Computation and Language · Computer Science 2026-03-16 Po-Jen Ko , Chen-Han Tsai , Yu-Shao Peng

An important unexplored aspect in previous work on user satisfaction estimation for Task-Oriented Dialogue (TOD) systems is their evaluation in terms of robustness for the identification of user dissatisfaction: current benchmarks for user…

Computation and Language · Computer Science 2024-08-21 Amin Abolghasemi , Zhaochun Ren , Arian Askari , Mohammad Aliannejadi , Maarten de Rijke , Suzan Verberne

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

The recent developments in the field of biomedicine have made large volumes of biomedical literature available to the medical practitioners. Due to the large size and lack of efficient searching strategies, medical practitioners struggle to…

Computation and Language · Computer Science 2018-05-16 M A H Zahid , Ankush Mittal , R. C. Joshi , G. Atluri

We developed a task-oriented dialogue framework structured as a Directed Acyclic Graph (DAG) of medical questions. The system integrates: (1) a systematic pipeline for transforming medical algorithms and guidelines into a clinical question…

Artificial Intelligence · Computer Science 2025-10-15 Rui Reis , Pedro Rangel Henriques , João Ferreira-Coimbra , Eva Oliveira , Nuno F. Rodrigues

Integrating novel medical concepts and relationships into existing ontologies can significantly enhance their coverage and utility for both biomedical research and clinical applications. Clinical notes, as unstructured documents rich with…

Artificial Intelligence · Computer Science 2025-11-21 Guanchen Wu , Yuzhang Xie , Huanwei Wu , Zhe He , Hui Shao , Xiao Hu , Carl Yang

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

This study presents an innovative approach to the application of large language models (LLMs) in clinical decision-making, focusing on OpenAI's ChatGPT. Our approach introduces the use of contextual prompts-strategically designed to include…

Artificial Intelligence · Computer Science 2023-08-22 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia

Effective patient care in digital healthcare requires large language models (LLMs) that not only answer questions but also actively gather critical information through well-crafted inquiries. This paper introduces HealthQ, a novel framework…

Computation and Language · Computer Science 2025-02-26 Ziyu Wang , Hao Li , Di Huang , Hye-Sung Kim , Chae-Won Shin , Amir M. Rahmani

Open-domain question answering (Open-QA) is a common task for evaluating large language models (LLMs). However, current Open-QA evaluations are criticized for the ambiguity in questions and the lack of semantic understanding in evaluators.…

Computation and Language · Computer Science 2024-05-28 Peiran Yao , Denilson Barbosa

We present a new text-to-SQL dataset for electronic health records (EHRs). The utterances were collected from 222 hospital staff members, including physicians, nurses, and insurance review and health records teams. To construct the QA…

Computation and Language · Computer Science 2026-03-06 Gyubok Lee , Hyeonji Hwang , Seongsu Bae , Yeonsu Kwon , Woncheol Shin , Seongjun Yang , Minjoon Seo , Jong-Yeup Kim , Edward Choi