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Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Several unsupervised image segmentation approaches have been proposed which eliminate the need for dense manually-annotated segmentation masks; current models separately handle either semantic segmentation (e.g., STEGO) or class-agnostic…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Dantong Niu , Xudong Wang , Xinyang Han , Long Lian , Roei Herzig , Trevor Darrell

Motivation: Networks underlie the generation and interpretation of many biological datasets: gene networks shed light on the regulatory structure of the genome, and cell networks can capture structure of the tumor micro-environment.…

Machine Learning · Statistics 2026-03-18 Bailey Andrew , Erica L. Harris , James A. Poulter , David R. Westhead , Luisa Cutillo

Accurately counting the number of cells in microscopy images is required in many medical diagnosis and biological studies. This task is tedious, time-consuming, and prone to subjective errors. However, designing automatic counting methods…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Mark A. Anastasio , Hua Li

For the semantic segmentation of images, state-of-the-art deep neural networks (DNNs) achieve high segmentation accuracy if that task is restricted to a closed set of classes. However, as of now DNNs have limited ability to operate in an…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Svenja Uhlemeyer , Matthias Rottmann , Hanno Gottschalk

Rapid growth in the field of quantitative digital image analysis is paving the way for researchers to make precise measurements about objects in an image. To compute quantities from the image such as the density of compressed materials or…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Marylesa Howard , Margaret C. Hock , B. T. Meehan , Leora Dresselhaus-Cooper

We propose an algorithm for segmenting natural images based on texture and color information, which leverages the co-sparse analysis model for image segmentation within a convex multilabel optimization framework. As a key ingredient of this…

Computer Vision and Pattern Recognition · Computer Science 2013-12-18 Claudia Nieuwenhuis , Daniel Cremers , Simon Hawe , Martin Kleinsteuber

We propose a parameter efficient Bayesian layer for hierarchical convolutional Gaussian Processes that incorporates Gaussian Processes operating in Wasserstein-2 space to reliably propagate uncertainty. This directly replaces convolving…

Machine Learning · Statistics 2021-04-29 Sebastian G. Popescu , David J. Sharp , James H. Cole , Konstantinos Kamnitsas , Ben Glocker

Accurate object segmentation is a crucial task in the context of robotic manipulation. However, creating sufficient annotated training data for neural networks is particularly time consuming and often requires manual labeling. To this end,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-09 Wout Boerdijk , Martin Sundermeyer , Maximilian Durner , Rudolph Triebel

Object segmentation is a crucial problem that is usually solved by using supervised learning approaches over very large datasets composed of both images and corresponding object masks. Since the masks have to be provided at pixel level,…

Computer Vision and Pattern Recognition · Computer Science 2019-12-02 Mickaël Chen , Thierry Artières , Ludovic Denoyer

Novel data acquisition schemes have been an emerging need for scanning microscopy based imaging techniques to reduce the time in data acquisition and to minimize probing radiation in sample exposure. Varies sparse sampling schemes have been…

Image and Video Processing · Electrical Eng. & Systems 2018-07-09 Yan Zhang , Xiang Huang , Nicola Ferrier , Emine B. Gulsoy , Charudatta Phatak

The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Yao Xue , Nilanjan Ray

In this paper, we introduce and study a novel segmentation method for 4D images based on surface evolution governed by a nonlinear partial differential equation, the generalized subjective surface equation. The new method uses 4D digital…

Numerical Analysis · Mathematics 2022-06-30 Markjoe Olunna Uba , Karol Mikula , Seol Ah Park

The segmentation of satellite images is a necessary step to perform object-oriented image classification, which has become relevant due to its applicability on images with a high spatial resolution. To perform object-oriented image…

Image and Video Processing · Electrical Eng. & Systems 2018-01-18 Wuilan Torres , Antonio Rueda-Toicen

Medical image segmentation is crucial in the field of medical imaging, aiding in disease diagnosis and surgical planning. Most established segmentation methods rely on supervised deep learning, in which clean and precise labels are…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Jiahua Dong , Yue Zhang , Qiuli Wang , Ruofeng Tong , Shihong Ying , Shaolin Gong , Xuanpu Zhang , Lanfen Lin , Yen-Wei Chen , S. Kevin Zhou

We propose an unsupervised image segmentation approach, that combines a variational energy functional and deep convolutional neural networks. The variational part is based on a recent multichannel multiphase Chan-Vese model, which is…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Nadja Gruber , Johannes Schwab , Sebastien Court , Elke Gizewski , Markus Haltmeier

Image partitioning, or segmentation without semantics, is the task of decomposing an image into distinct segments, or equivalently to detect closed contours. Most prior work either requires seeds, one per segment; or a threshold; or…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Steffen Wolf , Alberto Bailoni , Constantin Pape , Nasim Rahaman , Anna Kreshuk , Ullrich Köthe , Fred A. Hamprecht

The network flow optimization approach is offered for Bayesian segmentation of gray-scale and color images. It is supposed image pixels are characterized by a feature function taking finite number of arbitrary rational values (it can be…

Statistics Theory · Mathematics 2016-09-07 B. A. Zalesky

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape
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