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This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of…

We present p53-MDM2-Glucose model to study spatio-temporal properties of the system induced by glucose. The variation in glucose concentration level triggers the system at different states, namely, oscillation death (stabilized), sustain…

Subcellular Processes · Quantitative Biology 2015-04-03 Md. Jahoor Alam , R. K. Brojen Singh

A spatial-time method of description of alpha-decay of a nucleus is presented. The method is based on the quantum mechanical model of the alpha-decay of a compound nuclear system with the barrier. alpha-decay dynamics is described on the…

Nuclear Theory · Physics 2007-05-23 Sergei P. Maydanyuk , Vladislav S. Olkhovsky , Sergei V. Belchikov

An ensemble of pulse-coupled phase-oscillators is thoroughly analysed in the presence of a mean-field coupling and a dispersion of their natural frequencies. In spite of the analogies with the Kuramoto setup, a much richer scenario is…

Chaotic Dynamics · Physics 2017-11-06 Ekkehard Ullner , Antonio Politi

Spontaneous rhythmic oscillations are widely observed in various real-world systems. In particular, biological rhythms, which typically arise via synchronization of many self-oscillatory cells, often play important functional roles in…

Adaptation and Self-Organizing Systems · Physics 2021-06-11 Hiroya Nakao

Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors. A mathematical approach of this process is proposed…

Classical Analysis and ODEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

For most stochastic dynamical systems, variables which are tightly regulated tend to respond slowly to external changes. This idea is often discussed for applicable systems, within a linear response regime, through the Fluctuation…

General Physics · Physics 2017-11-15 Nash Rochman , Sean X. Sun

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · Physics 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

For distributions over discrete product spaces $\prod_{i=1}^n \Omega_i'$, Glauber dynamics is a Markov chain that at each step, resamples a random coordinate conditioned on the other coordinates. We show that $k$-Glauber dynamics, which…

Data Structures and Algorithms · Computer Science 2024-07-11 Holden Lee

We analyze both the static and dynamic fluctuation spectrum of the red-blood cell in a unified manner, using a simple model of the composite membrane. In this model, the two-dimensional spectrin network that forms the cytoskeleton is…

Soft Condensed Matter · Physics 2007-05-23 N. Gov , A. G. Zilman , S. Safran

Many organisms possess both a cell cycle to control DNA replication and a circadian clock to anticipate changes between day and night. In some cases, these two rhythmic systems are known to be coupled by specific, cross-regulatory…

Molecular Networks · Quantitative Biology 2016-04-12 Joris Paijmans , Mark Bosman , Pieter Rein ten Wolde , David K. Lubensky

Planetary turbulent flows are observed to self-organize into large scale structures such as zonal jets and coherent vortices. One of the simplest models of planetary turbulence is obtained by considering a barotropic flow on a beta-plane…

Atmospheric and Oceanic Physics · Physics 2014-02-13 Nikolaos A. Bakas , Petros J. Ioannou

A biochemical oscillator model, describing developmental stage of myxobacteria, is analyzed mathematically. Observations from numerical simulations show that in a certain range of parameters, the corresponding system of ordinary…

Dynamical Systems · Mathematics 2019-12-04 Hadi Taghvafard , Hildeberto Jardon-Kojakhmetov , Peter Szmolyan , Ming Cao

Automated verification of living organism models allows us to gain previously unknown knowledge about underlying biological processes. In this paper, we show the benefits to use parametric time Petri nets in order to analyze precisely the…

Logic in Computer Science · Computer Science 2015-06-23 Alexander Andreychenko , Morgan Magnin , Katsumi Inoue

The lattice dynamics of the metallic tin {\beta} and {\gamma} polymorphs has been studied by a combination of diffuse scattering, inelastic x-ray scattering and density functional perturbation theory. The non-symmorphic space group of the…

Models of active nematics in biological systems normally require complexity arising from the hydrodynamics involved at the microscopic level as well as the viscoelastic nature of the system. Here we show that a minimal, space-independent,…

Soft Condensed Matter · Physics 2022-06-27 Emmanuel L. C. VI M. Plan , Huong Le Thi , Julia M. Yeomans , Amin Doostmohammadi

Self-oscillations underlie many natural phenomena such as heartbeat, ocean waves, and the pulsation of variable stars. From pendulum clocks to the behavior of animal groups, self-oscillation is one of the keys to the understanding of…

The work is devoted to the analysis of cell population dynamics where cells make a choice between differentiation and apoptosis. This choice is based on the values of intracellular proteins whose concentrations are described by a system of…

Cell Behavior · Quantitative Biology 2016-03-30 Malay Banerjee , Vitaly Volpert

We present a mesoscopic approach to granular crystal dynamics, which comprises a three-dimensional finite-element model and a one-dimensional regularized contact model. The approach investigates the role of vibrational-energy trapping…

Materials Science · Physics 2016-02-09 Marcial Gonzalez , Jinkyu Yang , Chiara Daraio , Michael Ortiz

Some mechanisms of cardiac arrhythmias can be presented as a composition of elementary acts of block and reflection on the contacts of homogeneous areas of the conducting tissue. For study this phenomena we use an axiomatic one-dimensional…

Other Quantitative Biology · Quantitative Biology 2021-07-06 Sergii Kovalchuk