Geometric analysis of Oscillations in the Frzilator model
Dynamical Systems
2019-12-04 v2
Abstract
A biochemical oscillator model, describing developmental stage of myxobacteria, is analyzed mathematically. Observations from numerical simulations show that in a certain range of parameters, the corresponding system of ordinary differential equations displays stable and robust oscillations. In this work, we use geometric singular perturbation theory and blow-up method to prove the existence of a strongly attracting limit cycle. This cycle corresponds to a relaxation oscillation of an auxiliary system, whose singular perturbation nature originates from the small Michaelis-Menten constants of the biochemical model. In addition, we give a detailed description of the structure of the limit cycle, and the timescales along it.
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Cite
@article{arxiv.1912.00659,
title = {Geometric analysis of Oscillations in the Frzilator model},
author = {Hadi Taghvafard and Hildeberto Jardon-Kojakhmetov and Peter Szmolyan and Ming Cao},
journal= {arXiv preprint arXiv:1912.00659},
year = {2019}
}
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38 pages