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Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…

Computation and Language · Computer Science 2026-02-17 Xiao Wei , Bin Wen , Yuqin Lin , Kai Li , Mingyang gu , Xiaobao Wang , Longbiao Wang , Jianwu Dang

As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…

Machine Learning · Computer Science 2025-11-05 Rajan Das Gupta , Md Kishor Morol , Nafiz Fahad , Md Tanzib Hosain , Sumaya Binte Zilani Choya , Md Jakir Hossen

Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…

Computation and Language · Computer Science 2023-07-18 M. Zakaria Kurdi

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Hongming Li , Yong Fan

In this work, we propose a new parameter-efficient learning framework based on neural model reprogramming for cross-lingual speech recognition, which can \textbf{re-purpose} well-trained English automatic speech recognition (ASR) models to…

We present Bifocal RNN-T, a new variant of the Recurrent Neural Network Transducer (RNN-T) architecture designed for improved inference time latency on speech recognition tasks. The architecture enables a dynamic pivot for its runtime…

Audio and Speech Processing · Electrical Eng. & Systems 2021-08-05 Jonathan Macoskey , Grant P. Strimel , Ariya Rastrow

Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…

Computation and Language · Computer Science 2021-09-27 Akshay Valsaraj , Ithihas Madala , Nikhil Garg , Veeky Baths

Automatic speech recognition (ASR) of single channel far-field recordings with an unknown number of speakers is traditionally tackled by cascaded modules. Recent research shows that end-to-end (E2E) multi-speaker ASR models can achieve…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-11 Ilya Sklyar , Anna Piunova , Xianrui Zheng , Yulan Liu

End-to-end approaches for automatic speech recognition (ASR) benefit from directly modeling the probability of the word sequence given the input audio stream in a single neural network. However, compared to conventional ASR systems, these…

Audio and Speech Processing · Electrical Eng. & Systems 2020-02-19 Ankur Gandhe , Ariya Rastrow

Due to the subjective nature of current clinical evaluation, the need for automatic severity evaluation in dysarthric speech has emerged. DNN models outperform ML models but lack user-friendly explainability. ML models offer explainable…

Sound · Computer Science 2024-12-06 Yerin Choi , Jeehyun Lee , Myoung-Wan Koo

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

The a posteriori speech presence probability (SPP) is the fundamental component of noise power spectral density (PSD) estimation, which can contribute to speech enhancement and speech recognition systems. Most existing SPP estimators can…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-24 Shuai Tao , Jesper Rindom Jensen , Yang Xiang , Himavanth Reddy , Qingzheng Zhang , Mads Græsbøll Christensen

Self-supervised learning (SSL) based speech foundation models have been applied to a wide range of ASR tasks. However, their application to dysarthric and elderly speech via data-intensive parameter fine-tuning is confronted by in-domain…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-22 Shujie Hu , Xurong Xie , Mengzhe Geng , Zengrui Jin , Jiajun Deng , Guinan Li , Yi Wang , Mingyu Cui , Tianzi Wang , Helen Meng , Xunying Liu

Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide. In the absence of effective treatment options, early diagnosis is crucial for initiating management strategies to delay disease onset and slow down…

Machine Learning · Computer Science 2025-07-08 Saeed Jamshidiha , Alireza Rezaee , Farshid Hajati , Mojtaba Golzan , Raymond Chiong

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

Image and Video Processing · Electrical Eng. & Systems 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Computation and Language · Computer Science 2019-10-02 Bahman Mirheidari , Yilin Pan , Traci Walker , Markus Reuber , Annalena Venneri , Daniel Blackburn , Heidi Christensen

End-to-end automatic speech recognition (ASR) systems are increasingly popular due to their relative architectural simplicity and competitive performance. However, even though the average accuracy of these systems may be high, the…

Computation and Language · Computer Science 2021-09-14 Chao-Han Huck Yang , Linda Liu , Ankur Gandhe , Yile Gu , Anirudh Raju , Denis Filimonov , Ivan Bulyko

We recently developed SLM, a joint speech and language model, which fuses a pretrained foundational speech model and a large language model (LLM), while preserving the in-context learning capability intrinsic to the pretrained LLM. In this…

Computation and Language · Computer Science 2024-02-08 Mingqiu Wang , Izhak Shafran , Hagen Soltau , Wei Han , Yuan Cao , Dian Yu , Laurent El Shafey

Disease progression modeling (DPM) using longitudinal data is a challenging machine learning task. Existing DPM algorithms neglect temporal dependencies among measurements, make parametric assumptions about biomarker trajectories, do not…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen
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