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Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

Computation and Language · Computer Science 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

Computation and Language · Computer Science 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-20 Vrindha M. K. , Geethu V. , Anurenjan P. R. , Deepak S. , Sreeni K. G.

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Alzheimer's disease and related dementias(ADRD) affect nearly five million older adults in the United States, yet more than half remain undiagnosed. Speech-based natural language processing(NLP) offers a scalable approach for detecting…

Automatic speech recognition (ASR) technology can aid in the detection, monitoring, and assessment of depressive symptoms in individuals. ASR systems have been used as a tool to analyze speech patterns and characteristics that are…

Human-Computer Interaction · Computer Science 2023-08-17 Alice Othmani , Muhammad Muzammel

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

Alzheimer's dementia (AD) affects memory, thinking, and language, deteriorating person's life. An early diagnosis is very important as it enables the person to receive medical help and ensure quality of life. Therefore, leveraging…

Machine Learning · Computer Science 2023-04-06 Michail Chatzianastasis , Loukas Ilias , Dimitris Askounis , Michalis Vazirgiannis

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

Alzheimer's disease and related dementias (ADRD) affect one in five adults over 60, yet more than half of individuals with cognitive decline remain undiagnosed. Speech-based assessments show promise for early detection, as phonetic motor…

The state-of-art models for speech synthesis and voice conversion are capable of generating synthetic speech that is perceptually indistinguishable from bonafide human speech. These methods represent a threat to the automatic speaker…

Machine Learning · Computer Science 2019-07-11 Moustafa Alzantot , Ziqi Wang , Mani B. Srivastava

The development of noninvasive brain imaging such as resting-state functional magnetic resonance imaging (rs-fMRI) and its combination with AI algorithm provides a promising solution for the early diagnosis of Autism spectrum disorder…

Image and Video Processing · Electrical Eng. & Systems 2022-04-11 Fangyu Zhang , Yanjie Wei , Jin Liu , Yanlin Wang , Wenhui Xi , Yi Pan

The early diagnosis of Alzheimer's Disease (AD) through non invasive methods remains a significant healthcare challenge. We present NeuroXVocal, a novel dual-component system that not only classifies but also explains potential AD cases…

Speaker recognition systems based on Convolutional Neural Networks (CNNs) are often built with off-the-shelf backbones such as VGG-Net or ResNet. However, these backbones were originally proposed for image classification, and therefore may…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-01 Shaojin Ding , Tianlong Chen , Xinyu Gong , Weiwei Zha , Zhangyang Wang

This paper presents a speech intelligibility model based on automatic speech recognition (ASR), combining phoneme probabilities from deep neural networks (DNN) and a performance measure that estimates the word error rate from these…

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

Machine Learning · Computer Science 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

Computation and Language · Computer Science 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

Research related to automatically detecting Alzheimer's disease (AD) is important, given the high prevalence of AD and the high cost of traditional methods. Since AD significantly affects the content and acoustics of spontaneous speech,…

Computation and Language · Computer Science 2020-08-05 Aparna Balagopalan , Benjamin Eyre , Frank Rudzicz , Jekaterina Novikova