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Computational biology offers immense potential for reducing the high costs and protracted cycles of new drug development through adverse drug reaction (ADR) prediction. However, current methods remain impeded by drug data scarcity-induced…

Machine Learning · Computer Science 2026-01-06 Yuyan Pi , Min Jin , Wentao Xie , Xinhua Liu

Radiology report generation, as a key step in medical image analysis, is critical to the quantitative analysis of clinically informed decision-making levels. However, complex and diverse radiology reports with cross-source heterogeneity…

Automatic radiology report generation is essential to computer-aided diagnosis. Through the success of image captioning, medical report generation has been achievable. However, the lack of annotated disease labels is still the bottleneck of…

Computation and Language · Computer Science 2022-06-22 Jun Li , Shibo Li , Ying Hu , Huiren Tao

Neural image-to-text radiology report generation systems offer the potential to improve radiology reporting by reducing the repetitive process of report drafting and identifying possible medical errors. However, existing report generation…

Computation and Language · Computer Science 2021-04-14 Yasuhide Miura , Yuhao Zhang , Emily Bao Tsai , Curtis P. Langlotz , Dan Jurafsky

Chest X-ray (CXR) radiology report generation (RRG) models have shown rapid progress on automated metrics, yet their clinical utility remains uncertain due to limited qualitative evaluation by radiologists. We present CXRMate-2, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Aaron Nicolson , Elizabeth J. Cooper , Hwan-Jin Yoon , Claire McCafferty , Ramya Krishnan , Michelle Craigie , Nivene Saad , Jason Dowling , Ian A. Scott , Bevan Koopman

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Label distribution learning (LDL) is an effective method to predict the label description degree (a.k.a. label distribution) of a sample. However, annotating label distribution (LD) for training samples is extremely costly. So recent…

Machine Learning · Computer Science 2024-05-14 Yuheng Jia , Jiawei Tang , Jiahao Jiang

For the task of concurrently detecting and categorizing objects, the medical imaging community commonly adopts methods developed on natural images. Current state-of-the-art object detectors are comprised of two stages: the first stage…

Computer Vision and Pattern Recognition · Computer Science 2019-08-27 Gregor N. Ramien , Paul F. Jaeger , Simon A. A. Kohl , Klaus H. Maier-Hein

Computerized Adaptive Testing (CAT) has proven effective for efficient LLM evaluation on multiple-choice benchmarks, but modern LLM evaluation increasingly relies on generation tasks where outputs are scored continuously rather than marked…

Computation and Language · Computer Science 2026-01-21 Esma Balkır , Alice Pernthaller , Marco Basaldella , José Hernández-Orallo , Nigel Collier

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Noisy-label methods often estimate sample reliability from forward-space signals such as loss, confidence, or entropy. These signals indicate whether a sample is difficult to predict, but they do not directly test whether its observed label…

Machine Learning · Computer Science 2026-05-19 Ningkang Peng , Jingyang Mao , Xiaoqian Peng , Weiguang Qu , Yanhui Gu

Evaluating the quality of generated text is difficult, since traditional NLG evaluation metrics, focusing more on surface form than meaning, often fail to assign appropriate scores. This is especially problematic for AMR-to-text evaluation,…

Computation and Language · Computer Science 2022-05-25 Laura Zeidler , Juri Opitz , Anette Frank

Medical errors are a major public health concern and a leading cause of death worldwide. Many healthcare centers and hospitals use reporting systems where medical practitioners write a preliminary medical report and the report is later…

Information Retrieval · Computer Science 2020-05-01 Sean MacAvaney , Arman Cohan , Nazli Goharian , Ross Filice

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Recent advances in radiology report generation (RRG) have been driven by large paired image-text datasets; however, progress in neuro-oncology has been limited due to a lack of open paired image-report datasets. Here, we introduce BTReport,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Juampablo E. Heras Rivera , Dickson T. Chen , Tianyi Ren , Daniel K. Low , Asma Ben Abacha , Alberto Santamaria-Pang , Mehmet Kurt

Radiology Report Generation (RRG) is a critical step toward automating healthcare workflows, facilitating accurate patient assessments, and reducing the workload of medical professionals. Despite recent progress in Large Medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Sarosij Bose , Ravi K. Rajendran , Biplob Debnath , Konstantinos Karydis , Amit K. Roy-Chowdhury , Srimat Chakradhar

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Radiology reports are invaluable for clinical decision-making and hold great potential for automated analysis when structured into machine-readable formats. These reports often contain uncertainty, which we categorize into two distinct…

Computation and Language · Computer Science 2026-03-02 Paloma Rabaey , Jong Hak Moon , Jung-Oh Lee , Min Gwan Kim , Hangyul Yoon , Thomas Demeester , Edward Choi
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