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In clinics, a radiology report is crucial for guiding a patient's treatment. However, writing radiology reports is a heavy burden for radiologists. To this end, we present an automatic, multi-modal approach for report generation from a…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Shuxin Yang , Xian Wu , Shen Ge , S. Kevin Zhou , Li Xiao

Score-based generative models (SGMs) are a popular family of deep generative models that achieve leading image generation quality. Early studies extend SGMs to tackle class-conditional generation by coupling an unconditional SGM with the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Paul Kuo-Ming Huang , Si-An Chen , Hsuan-Tien Lin

Retrieval-augmented generation (RAG) grounds large language models in external medical knowledge, yet standard retrievers frequently surface hard negatives that are semantically close to the query but describe clinically distinct…

Information Retrieval · Computer Science 2026-04-07 Byeolhee Kim , Min-Kyung Kim , Young-Hak Kim , Tae-Joon Jeon

The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy…

Methodology · Statistics 2024-02-05 Vera Djordjilović , Erica Ponzi , Therese Haugdahl Nøst , Magne Thoresen

Matching patients to clinical trials demands a systematic and reasoned interpretation of documents which require significant expert-level background knowledge, over a complex set of well-defined eligibility criteria. Moreover, this…

Computation and Language · Computer Science 2024-10-01 Mael Jullien , Alex Bogatu , Harriet Unsworth , Andre Freitas

Reconstructing medical images from partial measurements is an important inverse problem in Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing solutions based on machine learning typically train a model to directly map…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Yang Song , Liyue Shen , Lei Xing , Stefano Ermon

Clinical language models (LMs) are increasingly applied to support clinical risk prediction from free-text notes, yet their uncertainty estimates often remain poorly calibrated and clinically unreliable. In this work, we propose Clinical…

Computation and Language · Computer Science 2026-04-27 Sizhe Wang , Ziqi Xu , Claire Najjuuko , Charles Alba , Chenyang Lu

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

Evaluating the quality of generated text automatically remains a significant challenge. Conventional reference-based metrics have been shown to exhibit relatively weak correlation with human evaluations. Recent research advocates the use of…

Computation and Language · Computer Science 2025-11-25 Xiao Wang , Daniil Larionov , Siwei Wu , Yiqi Liu , Steffen Eger , Nafise Sadat Moosavi , Chenghua Lin

Kernel-based methods are used in the context of Granger Causality to enable the identification of nonlinear causal relationships between time series variables. In this paper, we show that two state of the art kernel-based Granger Causality…

Machine Learning · Computer Science 2026-01-15 Fiona Murphy , Alessio Benavoli

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Clinical note generation aims to produce free-text summaries of a patient's condition and diagnostic process, with discharge instructions being a representative long-form example. While recent LLM-based methods pre-trained on general…

Computation and Language · Computer Science 2025-08-12 Lo Pang-Yun Ting , Chengshuai Zhao , Yu-Hua Zeng , Yuan Jee Lim , Kun-Ta Chuang , Huan Liu

Vision--language models (VLMs) for radiology report generation (RRG) can produce long-form chest CT reports from volumetric scans and show strong potential to improve radiology workflow efficiency and consistency. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Chenyu Wang , Weicheng Dai , Han Liu , Wenchao Li , Kayhan Batmanghelich

The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Bootstrapping labels from radiology reports has become the scalable alternative to provide inexpensive ground truth for medical imaging. Because of the domain specific nature, state-of-the-art report labeling tools are predominantly…

Computation and Language · Computer Science 2019-10-03 Tobi Olatunji , Li Yao

The Granger framework is useful for discovering causal relations in time-varying signals. However, most Granger causality (GC) methods are developed for densely sampled timeseries data. A substantially different setting, particularly common…

Machine Learning · Computer Science 2024-12-19 Minh Nguyen , Gia H. Ngo , Mert R. Sabuncu

Automatic radiology report generation has been an attracting research problem towards computer-aided diagnosis to alleviate the workload of doctors in recent years. Deep learning techniques for natural image captioning are successfully…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Yixiao Zhang , Xiaosong Wang , Ziyue Xu , Qihang Yu , Alan Yuille , Daguang Xu

Chest radiography is the most common radiographic examination performed in daily clinical practice for the detection of various heart and lung abnormalities. The large amount of data to be read and reported, with more than 100 studies per…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Sebastian Gündel , Arnaud A. A. Setio , Florin C. Ghesu , Sasa Grbic , Bogdan Georgescu , Andreas Maier , Dorin Comaniciu

The current gold standard for evaluating generated chest x-ray (CXR) reports is through radiologist annotations. However, this process can be extremely time-consuming and costly, especially when evaluating large numbers of reports. In this…

Computation and Language · Computer Science 2024-08-13 Alyssa Huang , Oishi Banerjee , Kay Wu , Eduardo Pontes Reis , Pranav Rajpurkar
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