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Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Large Language Models (LLMs) have acquired ubiquitous attention for their performances across diverse domains. Our study here searches through LLMs' cognitive abilities and confidence dynamics. We dive deep into understanding the alignment…

Computation and Language · Computer Science 2023-09-29 Aniket Kumar Singh , Suman Devkota , Bishal Lamichhane , Uttam Dhakal , Chandra Dhakal

The utilization of large language models (LLMs) in the Healthcare domain has generated both excitement and concern due to their ability to effectively respond to freetext queries with certain professional knowledge. This survey outlines the…

Computation and Language · Computer Science 2025-01-28 Kai He , Rui Mao , Qika Lin , Yucheng Ruan , Xiang Lan , Mengling Feng , Erik Cambria

Uncertainty estimation is a significant issue for current large language models (LLMs) that are generally poorly calibrated and over-confident, especially with reinforcement learning from human feedback (RLHF). Unlike humans, whose…

Computation and Language · Computer Science 2024-05-13 Ruixin Yang , Dheeraj Rajagopal , Shirley Anugrah Hayati , Bin Hu , Dongyeop Kang

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Recent advancements in Large Language Models (LLMs) have attracted considerable interest among researchers to leverage these models to enhance Recommender Systems (RSs). Existing work predominantly utilizes LLMs to generate knowledge-rich…

Information Retrieval · Computer Science 2024-07-25 Zhongxiang Sun , Zihua Si , Xiaoxue Zang , Kai Zheng , Yang Song , Xiao Zhang , Jun Xu

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works…

Computation and Language · Computer Science 2024-10-18 Humza Naveed , Asad Ullah Khan , Shi Qiu , Muhammad Saqib , Saeed Anwar , Muhammad Usman , Naveed Akhtar , Nick Barnes , Ajmal Mian

LLM Ensemble -- which involves the comprehensive use of multiple large language models (LLMs), each aimed at handling user queries during downstream inference, to benefit from their individual strengths -- has gained substantial attention…

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of…

The emergence of Large Language Models (LLMs) has revealed a growing need for human-AI collaboration, especially in creative decision-making scenarios where trust and reliance are paramount. Through human studies and model evaluations on…

Computation and Language · Computer Science 2024-10-07 Manasi Sharma , Ho Chit Siu , Rohan Paleja , Jaime D. Peña

The integration of Large Language Models (LLMs) into healthcare holds significant potential to enhance diagnostic accuracy and support medical treatment planning. These AI-driven systems can analyze vast datasets, assisting clinicians in…

Computation and Language · Computer Science 2025-04-15 Diogo Sousa , Guilherme Barbosa , Catarina Rocha , Dulce Oliveira

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

Biomedical text mining and question-answering are essential yet highly demanding tasks, particularly in the face of the exponential growth of biomedical literature. In this work, we present our participation in the 13th edition of the…

Computation and Language · Computer Science 2025-08-05 Dimitra Panou , Alexandros C. Dimopoulos , Manolis Koubarakis , Martin Reczko

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Computers and Society · Computer Science 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Large language models (LLMs) often need to balance their internal parametric knowledge with external information, such as user beliefs and content from retrieved documents, in real-world scenarios like RAG or chat-based systems. A model's…

Computation and Language · Computer Science 2026-04-27 Shuowei Li , Haoxin Li , Wenda Chu , Yi Fang

Large Language Models (LLMs) deliver powerful AI capabilities but face deployment challenges due to high resource costs and latency, whereas Small Language Models (SLMs) offer efficiency and deployability at the cost of reduced performance.…

Artificial Intelligence · Computer Science 2025-05-13 Yi Chen , JiaHao Zhao , HaoHao Han
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