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Large Language Models (LLMs) have demonstrated their transformative potential across numerous disciplinary studies, reshaping the existing research methodologies and fostering interdisciplinary collaboration. However, a systematic…

Computation and Language · Computer Science 2025-07-14 Lu Xiang , Yang Zhao , Yaping Zhang , Chengqing Zong

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

Computation and Language · Computer Science 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…

Artificial Intelligence · Computer Science 2025-08-27 Armin Berger , Sarthak Khanna , David Berghaus , Rafet Sifa

Digital technologies have long been explored as a complement to standard procedure in mental health research and practice, ranging from the management of electronic health records to app-based interventions. The recent emergence of large…

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Large language models (LLMs) have achieved remarkable progress across domains and applications but face challenges such as high fine-tuning costs, inference latency, limited edge deployability, and reliability concerns. Small language…

Computation and Language · Computer Science 2025-11-06 Fali Wang , Jihai Chen , Shuhua Yang , Ali Al-Lawati , Linli Tang , Hui Liu , Suhang Wang

Large language models (LLMs) provide detailed and impressive responses to queries in English. However, are they really consistent at responding to the same query in other languages? The popular way of evaluating for multilingual performance…

Computation and Language · Computer Science 2025-05-29 Ashim Gupta , Maitrey Mehta , Zhichao Xu , Vivek Srikumar

Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances…

Computation and Language · Computer Science 2024-11-12 Iñigo Alonso , Maite Oronoz , Rodrigo Agerri

Large language models (LLMs) have shown their potential in biomedical fields. However, how the public uses them for healthcare purposes such as medical Q\&A, self-diagnosis, and daily healthcare information seeking is under-investigated.…

Computers and Society · Computer Science 2024-09-13 Yunpeng Xiao , Kyrie Zhixuan Zhou , Yueqing Liang , Kai Shu

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Large Language Models (LLMs) have demonstrated exceptional capabilities, yet selecting the most reliable response from multiple LLMs remains a challenge, particularly in resource-constrained settings. Existing approaches often depend on…

Computation and Language · Computer Science 2025-10-06 Aakriti Agrawal , Rohith Aralikatti , Anirudh Satheesh , Souradip Chakraborty , Amrit Singh Bedi , Furong Huang

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

While training large language models (LLMs) from scratch can generate models with distinct functionalities and strengths, it comes at significant costs and may result in redundant capabilities. Alternatively, a cost-effective and compelling…

Computation and Language · Computer Science 2024-01-23 Fanqi Wan , Xinting Huang , Deng Cai , Xiaojun Quan , Wei Bi , Shuming Shi

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…

Information Retrieval · Computer Science 2025-05-16 Alejo Lopez-Avila , Jinhua Du

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes