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We introduce the sum channel, a new channel model motivated by applications in distributed storage and DNA data storage. In the error-free case, it takes as input an $\ell$-row binary matrix and outputs an $(\ell+1)$-row matrix whose first…

Information Theory · Computer Science 2026-04-14 Lyan Abboud , Eitan Yaakobi

This paper considers coding for so-called partially stuck (defect) memory cells. Such memory cells can only store partial information as some of their levels cannot be used fully due to, e.g., wearout. First, we present new constructions…

Information Theory · Computer Science 2022-02-16 Haider Al Kim , Sven Puchinger , Ludo Tolhuizen , Antonia Wachter-Zeh

Motivated by DNA-based data storage, we investigate a system where digital information is stored in an unordered set of several vectors over a finite alphabet. Each vector begins with a unique index that represents its position in the whole…

Information Theory · Computer Science 2019-01-23 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

The noise model of deletions poses significant challenges in coding theory, with basic questions like the capacity of the binary deletion channel still being open. In this paper, we study the harder model of worst-case deletions, with a…

Information Theory · Computer Science 2014-11-26 Venkatesan Guruswami , Carol Wang

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

Motivated by average-case trace reconstruction and coding for portable DNA-based storage systems, we initiate the study of \emph{coded trace reconstruction}, the design and analysis of high-rate efficiently encodable codes that can be…

Information Theory · Computer Science 2019-09-11 Mahdi Cheraghchi , Ryan Gabrys , Olgica Milenkovic , João Ribeiro

With recent advancements in next-generation data storage, especially in biological molecule-based storage, insertion, deletion, and substitution (IDS) error-correcting codes have garnered increased attention. However, a universal method for…

Information Theory · Computer Science 2025-11-11 Alan J. X. Guo , Mengyi Wei , Yufan Dai , Yali Wei , Pengchen Zhang

DNA language models have revolutionized our ability to understand and design DNA sequences--the fundamental language of life--with unprecedented precision, enabling transformative applications in therapeutics, synthetic biology, and gene…

Genomics · Quantitative Biology 2025-09-24 Zaixi Zhang , Ruofan Jin , Le Cong , Mengdi Wang

Binary maximum distance separable (MDS) array codes are a special class of erasure codes for distributed storage that not only provide fault tolerance with minimum storage redundancy but also achieve low computational complexity. They are…

Information Theory · Computer Science 2019-06-24 Hanxu Hou , Yunghsiang Han , Patrick P. C. Lee , Yuchong Hu , Hui Li

Distributed storage systems provide reliable access to data through redundancy spread over individually unreliable nodes. Application scenarios include data centers, peer-to-peer storage systems, and storage in wireless networks. Storing…

Networking and Internet Architecture · Computer Science 2008-03-06 Alexandros G. Dimakis , P. Brighten Godfrey , Yunnan Wu , Martin J. Wainwright , Kannan Ramchandran

DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For…

Emerging Technologies · Computer Science 2024-03-22 Yixun Wei , Wenlong Wang , Huibing Dong , Bingzhe Li , David Du

Segmenting biomarkers in medical images is crucial for various biotech applications. Despite advances, Transformer and CNN based methods often struggle with variations in staining and morphology, limiting feature extraction. In medical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Saad Wazir , Daeyoung Kim

The main obstacles for the practical deployment of DNA-based data storage platforms are the prohibitively high cost of synthetic DNA and the large number of errors introduced during synthesis. In particular, synthetic DNA products contain…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Chao Pan , S. M. Hossein Tabatabaei Yazdi , S Kasra Tabatabaei , Alvaro G. Hernandez , Charles Schroeder , Olgica Milenkovic

MDS array codes are widely used in storage systems due to their computationally efficient encoding and decoding procedures. An MDS code with $r$ redundancy nodes can correct any $r$ node erasures by accessing all the remaining information…

Information Theory · Computer Science 2016-03-04 Zhiying Wang , Itzhak Tamo , Jehoshua Bruck

Correcting insertions/deletions as well as substitution errors simultaneously plays an important role in DNA-based storage systems as well as in classical communications. This paper deals with the fundamental task of constructing codes that…

Information Theory · Computer Science 2020-05-20 Ilia Smagloy , Lorenz Welter , Antonia Wachter-Zeh , Eitan Yaakobi

We propose coding techniques that limit the length of homopolymers runs, ensure the GC-content constraint, and are capable of correcting a single edit error in strands of nucleotides in DNA-based data storage systems. In particular, for…

Information Theory · Computer Science 2020-01-10 Tuan Thanh Nguyen , Kui Cai , Kees A. Schouhamer Immink , Han Mao Kiah

Network codes designed specifically for distributed storage systems have the potential to provide dramatically higher storage efficiency for the same availability. One main challenge in the design of such codes is the exact repair problem:…

Information Theory · Computer Science 2011-09-02 Dimitris S. Papailiopoulos , Jianqiang Luo , Alexandros G. Dimakis , Cheng Huang , Jin Li

This work deals with error correction for non-volatile memories that are partially defective at some levels. Such memory cells can only store incomplete information since some of their levels cannot be utilized entirely due to, e.g.,…

Information Theory · Computer Science 2022-08-23 Haider Al Kim , Kai Jie Chan

In coding theory, handling errors that occur when symbols are inserted or deleted from a transmitted message is a long-standing challenge. Optimising redundancy for insertion and deletion channels remains a key open problem with significant…

Information Theory · Computer Science 2026-02-02 Anamika Singh , Abhay Kumar Singh

Codes are widely used in many engineering applications to offer robustness against noise. In large-scale systems there are several types of noise that can affect the performance of distributed machine learning algorithms -- straggler nodes,…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-01-30 Kangwook Lee , Maximilian Lam , Ramtin Pedarsani , Dimitris Papailiopoulos , Kannan Ramchandran