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AI agents are an exciting new research direction, and agent development is driven by benchmarks. Our analysis of current agent benchmarks and evaluation practices reveals several shortcomings that hinder their usefulness in real-world…

Machine Learning · Computer Science 2024-07-02 Sayash Kapoor , Benedikt Stroebl , Zachary S. Siegel , Nitya Nadgir , Arvind Narayanan

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

While previous AI Scientist systems can generate novel findings, they often lack the focus to produce scientifically valuable contributions that address pressing human-defined challenges. We introduce DeepScientist, a system designed to…

Computation and Language · Computer Science 2025-10-01 Yixuan Weng , Minjun Zhu , Qiujie Xie , Qiyao Sun , Zhen Lin , Sifan Liu , Yue Zhang

With the increasing use of large language models (LLMs) for generating answers to biomedical questions, it is crucial to evaluate the quality of the generated answers and the references provided to support the facts in the generated…

Computation and Language · Computer Science 2026-02-10 Deepak Gupta , Davis Bartels , Dina Demner-Fushman

The rapid growth of biomedical literature and curated databases has made it increasingly difficult for researchers to systematically connect biomarker mechanisms to actionable drug combination hypotheses. We present AI Co-Scientist (CoDHy),…

Computation and Language · Computer Science 2026-03-03 Raneen Younis , Suvinava Basak , Lukas Chavez , Zahra Ahmadi

Scientific research is being reshaped by AI systems that move beyond isolated assistance toward longer-horizon workflows spanning literature grounding, hypothesis generation, experimentation, validation, reporting, and revision. This shift…

We present HippoCamp, a new benchmark designed to evaluate agents' capabilities on multimodal file management. Unlike existing agent benchmarks that focus on tasks like web interaction, tool use, or software automation in generic settings,…

Artificial Intelligence · Computer Science 2026-04-02 Zhe Yang , Shulin Tian , Kairui Hu , Shuai Liu , Hoang-Nhat Nguyen , Yichi Zhang , Zujin Guo , Mengying Yu , Zinan Zhang , Jingkang Yang , Chen Change Loy , Ziwei Liu

The literature has witnessed an emerging interest in AI agents for automated assessment of scientific papers. Existing benchmarks focus primarily on the computational aspect of this task, testing agents' ability to reproduce or replicate…

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

Frontier AI agents show increasing promise as scientific research assistants, and may eventually be useful for extended, open-ended research workflows. However, in order to use agents for novel research, we must first assess the underlying…

Artificial intelligence (AI) technologies (re-)shape modern life, driving innovation in a wide range of sectors. However, some AI systems have yielded unexpected or undesirable outcomes or have been used in questionable manners. As a…

In scientific research, analysis requires accurately interpreting complex multimodal knowledge, integrating evidence from different sources, and drawing inferences grounded in domain-specific knowledge. However, current artificial…

Computation and Language · Computer Science 2026-02-13 Xuehang Guo , Zhiyong Lu , Tom Hope , Qingyun Wang

HIKMA Semi-Autonomous Conference is the first experiment in reimagining scholarly communication through an end-to-end integration of artificial intelligence into the academic publishing and presentation pipeline. This paper presents the…

Multiagent Systems · Computer Science 2025-10-27 Zain Ul Abideen Tariq , Mahmood Al-Zubaidi , Uzair Shah , Marco Agus , Mowafa Househ

Autonomous language-model agents are increasingly evaluated on long-horizon tool-use tasks, but existing benchmarks rarely capture the complexity and nuance of real scientific work. To address this gap, we introduce Collider-Bench, a…

Machine Learning · Computer Science 2026-05-15 Darius A. Faroughy , Sofia Palacios Schweitzer , Ian Pang , Siddharth Mishra-Sharma , David Shih

Autonomous AI research agents aim to accelerate scientific discovery by automating the research pipeline, from hypothesis generation to peer review. However, existing benchmarks rarely test a fundamental bottleneck: whether Large Language…

Machine Learning · Computer Science 2026-05-29 Sy-Tuyen Ho , Minghui Liu , Huy Nghiem , Furong Huang

Developing safe, aligned agentic AI systems requires comprehensive empirical testing, yet many existing benchmarks neglect crucial themes aligned with biology and economics, both time-tested fundamental sciences describing our needs and…

Multiagent Systems · Computer Science 2025-12-01 Roland Pihlakas

Scientific embodied agents play a crucial role in modern laboratories by automating complex experimental workflows. Compared to typical household environments, laboratory settings impose significantly higher demands on perception of…

As single-cell RNA sequencing datasets grow in adoption, scale, and complexity, data analysis remains a bottleneck for many research groups. Although frontier AI agents have improved dramatically at software engineering and general data…

Genomics · Quantitative Biology 2026-02-11 Kenny Workman , Zhen Yang , Harihara Muralidharan , Aidan Abdulali , Hannah Le

The rapid spread of misinformation in the digital era poses significant challenges to public discourse, necessitating robust and scalable fact-checking solutions. Traditional human-led fact-checking methods, while credible, struggle with…

Artificial Intelligence · Computer Science 2025-06-24 Tam Trinh , Manh Nguyen , Truong-Son Hy
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