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Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Recognizing multiple labels of images is a fundamental but challenging task in computer vision, and remarkable progress has been attained by localizing semantic-aware image regions and predicting their labels with deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2017-12-21 Tianshui Chen , Zhouxia Wang , Guanbin Li , Liang Lin

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely.…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jacob C. Reinhold , Yufan He , Shizhong Han , Yunqiang Chen , Dashan Gao , Junghoon Lee , Jerry L. Prince , Aaron Carass

Recognition and reasoning are two pillars of visual understanding. However, these tasks have an imbalance in focus; whereas recent advances in neural networks have shown strong empirical performance in visual recognition, there has been…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Calvin Luo , Boqing Gong , Ting Chen , Chen Sun

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Boram Song , Seoung Wan Chae , Jin Tae Kwak

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains.…

Artificial Intelligence · Computer Science 2025-05-27 Shaohao Rui , Kaitao Chen , Weijie Ma , Xiaosong Wang

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

Extending Reinforcement Learning with Verifiable Rewards (RLVR) to multimodal large language models (MLLMs) faces a fundamental challenge: their responses inherently interleave perception-related tokens, which ground visual content, with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinda Lu , Junkang Wu , Jinghan Li , Kexin Huang , Shuo Yang , Guoyin Wang , Jiancan Wu , Xiang Wang , Xiangnan He

Vision-language models (VLMs) have achieved remarkable success across diverse tasks. However, concerns about their trustworthiness persist, particularly regarding tendencies to lean more on textual cues than visual evidence and the risk of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Shizhan Gong , Minda Hu , Qiyuan Zhang , Chen Ma , Qi Dou

Chain of Thought (CoT) reasoning enhances logical performance by decomposing complex tasks, yet its multimodal extension faces a trade-off. The prevailing Thinking with Images paradigm achieves visual refocusing by explicitly cropping image…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Jizheng Ma , Xiaofei Zhou , Geyuan Zhang , Yanlong Song , Han Yan

Deep models that are both effective and explainable are desirable in many settings; prior explainable models have been unimodal, offering either image-based visualization of attention weights or text-based generation of post-hoc…

Artificial Intelligence · Computer Science 2018-02-23 Dong Huk Park , Lisa Anne Hendricks , Zeynep Akata , Anna Rohrbach , Bernt Schiele , Trevor Darrell , Marcus Rohrbach

When thinking with images, humans rarely rely on a single glance: they revisit visual evidence while reasoning. In contrast, most Multimodal Language Models encode an image once to key-value cache and then reason purely in text, making it…

Computation and Language · Computer Science 2026-05-08 Jiwan Chung , Junhyeok Kim , Siyeol Kim , Jaeyoung Lee , Min Soo Kim , Youngjae Yu

Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…

Quantitative Methods · Quantitative Biology 2025-10-08 Anni Tziakouri , Filippo Menolascina

Existing super-resolution models for pathology images can only work in fixed integer magnifications and have limited performance. Though implicit neural network-based methods have shown promising results in arbitrary-scale super-resolution…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Linhao Qu , Minghong Duan , Zhiwei Yang , Manning Wang , Zhijian Song

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope