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Accurate analysis of pathological images is essential for automated tumor diagnosis but remains challenging due to high structural similarity and subtle morphological variations in tissue images. Current vision-language (VL) models often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yating Huang , Ziyan Huang , Lintao Xiang , Qijun Yang , Hujun Yin

Evaluation of multimodal reasoning models is typically reduced to a single accuracy score, implicitly treating reasoning as a unitary capability. We introduce MathLens, a benchmark of textbook-style geometry problems that exposes this…

Computation and Language · Computer Science 2026-05-08 Jiwan Chung , Neel Joshi , Pratyusha Sharma , Youngjae Yu , Vibhav Vineet

Large language models (LLMs) can achieve strong reasoning performance with sufficient computation, but they do not inherently know how much computation a task requires. We study budgeted inference-time reasoning for multiple tasks under a…

Artificial Intelligence · Computer Science 2026-01-08 Muyang Zhao , Qi Qi , Hao Sun

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Metadata are general characteristics of the data in a well-curated and condensed format, and have been proven to be useful for decision making, knowledge discovery, and also heterogeneous data organization of biobank. Among all data types…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Wei-Hung Weng , Yuannan Cai , Angela Lin , Fraser Tan , Po-Hsuan Cameron Chen

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Artificial Intelligence · Computer Science 2026-05-26 Jinyue Li , Yuci Liang , Qiankun Li , Xinheng Lyu , Jiayu Qian , Huabao Chen , Kun Wang , Zhigang Zeng , Anil Anthony Bharath , Yang Liu

Latent reasoning enables reasoning over continuous hidden states rather than explicit tokens, avoiding the language bottleneck and inference overhead of chain-of-thought for medical VQA. However, existing methods suffer from modality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Qiaoru Li , Shaotian Liang , Jintao Chen , Haoran Sun , Yuxiang Cai , Jianwei Yin , Yankai Jiang

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Medical imaging is a cornerstone of therapy and diagnosis in modern medicine. However, the choice of imaging modality for a particular theranostic task typically involves trade-offs between the feasibility of using a particular modality…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mayur Mallya , Ghassan Hamarneh

Large reasoning models (LRMs) often consume excessive tokens, inflating computational cost and latency. More broadly, in goal reaching sequential decision problems we often want to reach the goal quickly, and LRM reasoning can be viewed…

Machine Learning · Computer Science 2026-05-27 Alex Ayoub , Kavosh Asadi , Dale Schuurmans , Csaba Szepesvári , Karim Bouyarmane

Motivation: Medical image analysis involves tasks to assist physicians in qualitative and quantitative analysis of lesions or anatomical structures, significantly improving the accuracy and reliability of diagnosis and prognosis.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Mingzhe Hu , Jiahan Zhang , Luke Matkovic , Tian Liu , Xiaofeng Yang

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

For Artificial Intelligence to have a greater impact in biology and medicine, it is crucial that recommendations are both accurate and transparent. In other domains, a neurosymbolic approach of multi-hop reasoning on knowledge graphs has…

Machine Learning · Computer Science 2022-10-10 Gavin Edwards , Sebastian Nilsson , Benedek Rozemberczki , Eliseo Papa

Purpose: AI in radiology is hindered chiefly by: 1) Requiring large annotated data sets. 2) Non-generalizability that limits deployment to new scanners / institutions. And 3) Inadequate explainability and interpretability. We believe that…

Artificial Intelligence · Computer Science 2020-08-07 Joseph Stember , Hrithwik Shalu

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is…

Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction. Here, we propose to exploit the interpretability of deep…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Yuhao Niu , Lin Gu , Feng Lu , Feifan Lv , Zongji Wang , Imari Sato , Zijian Zhang , Yangyan Xiao , Xunzhang Dai , Tingting Cheng

Multimodal latent reasoning has emerged as a promising paradigm that replaces explicit Chain-of-Thought (CoT) decoding with implicit feature propagation, simultaneously enhancing representation informativeness and reducing inference…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Yudong Han , Yong Wang , Zaiquan Yang , Zhen Qu , Liyuan Pan , Xiangxiang Chu

An integrated approach is proposed across visual and textual data to both determine and justify a medical diagnosis by a neural network. As deep learning techniques improve, interest grows to apply them in medical applications. To enable a…

Machine Learning · Computer Science 2019-07-15 Graham Spinks , Marie-Francine Moens