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We study the asymptotic dynamical properties of Boolean networks without local negative cycle. While the properties of Boolean networks without local cycle or without local positive cycle are rather well understood, recent literature raises…

Combinatorics · Mathematics 2016-10-18 Paul Ruet

To simplify the analysis of Boolean networks, a reduction in the number of components is often considered. A popular reduction method consists in eliminating components that are not autoregulated, using variable substitution. In this work,…

Discrete Mathematics · Computer Science 2024-03-27 Robert Schwieger , Elisa Tonello

Boolean networks are a general model of interacting entities, with applications to biological phenomena such as gene regulation. Attractors play a central role, and the schedule of entities update is a priori unknown. This article presents…

Discrete Mathematics · Computer Science 2020-01-22 Florian Bridoux , Caroline Gaze-Maillot , Kévin Perrot , Sylvain Sené

In this paper we study the dynamical behavior of Boolean networks with firing memory, namely Boolean networks whose vertices are updated synchronously depending on their proper Boolean local transition functions so that each vertex remains…

Discrete Mathematics · Computer Science 2022-04-25 Eric Goles , Fabiola Lobos , Gonzalo A. Ruz , Sylvain Sené

We consider the Cartesian product X of n finite intervals of integers and a map F from X to itself. As main result, we establish an upper bound on the number of fixed points for F which only depends on X and on the topology of the positive…

Discrete Mathematics · Computer Science 2008-12-01 Adrien Richard

Many machine learning algorithms rely on iterative updates of uncertainty representations, ranging from variational inference and expectation-maximization, to reinforcement learning, continual learning, and multi-agent learning. In the…

Machine Learning · Computer Science 2026-02-05 Michele Caprio , Siu Lun Chau , Krikamol Muandet

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are…

Molecular Networks · Quantitative Biology 2007-05-23 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

Automata networks, and in particular Boolean networks, are used to model diverse networks of interacting entities. The interaction graph of an automata network is its most important parameter, as it represents the overall architecture of…

Formal Languages and Automata Theory · Computer Science 2023-09-21 Maximilien Gadouleau

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

Boolean networks are dynamical models of disease development in which the activation levels of genes are represented by binary variables. Given a Boolean network, controls represent mutations or medical treatments that fix the activation…

Optimization and Control · Mathematics 2026-04-02 Kyungduk Moon , Kangbok Lee , Loïc Paulevé

An automata network is a finite graph where each node holds a state from some finite alphabet and is equipped with an update function that changes its state according to the configuration of neighboring states. More concisely, it is given…

Computational Complexity · Computer Science 2020-04-28 Florian Bridoux , Maximilien Gadouleau , Guillaume Theyssier

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein

Boolean networks at the critical point have been a matter of debate for many years as, e.g., scaling of number of attractor with system size. Recently it was found that this number scales superpolynomially with system size, contrary to a…

Disordered Systems and Neural Networks · Physics 2009-11-10 Konstantin Klemm , Stefan Bornholdt

Boolean network (BN) is a simple model widely used to study complex dynamic behaviour of biological systems. Nonetheless, it might be difficult to gather enough data to precisely capture the behavior of a biological system into a set of…

Molecular Networks · Quantitative Biology 2020-09-02 Lubos Brim , Samuel Pastva , David Safranek , Eva Smijakova

Recurrent neural networks are widely used in speech and language processing. Due to dependency on the past, standard algorithms for training these models, such as back-propagation through time (BPTT), cannot be efficiently parallelised.…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-07 Zhengxiong Wang , Anton Ragni

Linear network coding transmits data through networks by letting the intermediate nodes combine the messages they receive and forward the combinations towards their destinations. The solvability problem asks whether the demands of all the…

Information Theory · Computer Science 2014-12-18 Maximilien Gadouleau , Adrien Richard , Eric Fanchon

Boolean networks (BNs) are widely used to model the qualitative dynamics of biological systems. Besides the logical rules determining the evolution of each component with respect to the state of its regulators, the scheduling of component…

Logic in Computer Science · Computer Science 2019-06-03 Thomas Chatain , Stefan Haar , Juraj Kolčák , Loïc Paulevé , Aalok Thakkar

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same cell, and the activation of Notch in presence of Delta in…

Discrete Mathematics · Computer Science 2020-07-31 Elisa Tonello , Heike Siebert