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Boolean Networks (BNs) serve as a fundamental modeling framework for capturing complex dynamical systems across various domains, including systems biology, computational logic, and artificial intelligence. A crucial property of BNs is the…

Logic in Computer Science · Computer Science 2025-06-19 Mohimenul Kabir , Van-Giang Trinh , Samuel Pastva , Kuldeep S Meel

For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems. In this work, we propose a novel…

Adaptation and Self-Organizing Systems · Physics 2009-09-30 Christian Darabos , Marco Tomassini , Mario Giacobini

This paper investigates the stabilization of probabilistic Boolean networks (PBNs) via a novel pinning control strategy based on network structure. In a PBN, the evolution equation of each gene switches among a collection of candidate…

Systems and Control · Electrical Eng. & Systems 2020-10-26 Lin Lin , Jinde Cao , Jianquan Lu , Jie Zhong

In this paper, we address the formal characterization of targets triggering cellular trans-differentiation in the scope of Boolean networks with asynchronous dynamics. Given two fixed points of a Boolean network, we are interested in all…

Discrete Mathematics · Computer Science 2016-11-07 Hugues Mandon , Stefan Haar , Loïc Paulevé

AND-OR networks are Boolean networks where each coordinate function is either the AND or OR logical operator. We study the number of fixed points of these Boolean networks in the case that they have a wiring diagram with chain topology. We…

Combinatorics · Mathematics 2016-09-09 Alan Veliz-Cuba , Lauren Geiser

In the applications of Boolean networks to modeling biological systems, an important computational problem is the detection of the fixed points of these networks. This is an NP-complete problem in general. There have been various attempts…

Quantitative Methods · Quantitative Biology 2014-04-23 Yi Ming Zou

Boolean networks may be viewed as idealizations of biological genetic networks, where each node is represented by an on-off switch which is a function of the binary output from some other nodes. We evolve connectivity in a single Boolean…

Biological Physics · Physics 2016-09-08 Stefan Bornholdt , Kim Sneppen

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

Boolean networks are popular tools for the exploration of qualitative dynamical properties of biological systems. Several dynamical interpretations have been proposed based on the same logical structure that captures the interactions…

Discrete Mathematics · Computer Science 2022-03-04 Aurélien Naldi , Adrien Richard , Elisa Tonello

Boolean networks (BNs) are discrete-time systems where nodes are inter-connected (here we call such connection rule among nodes as network structure), and the dynamics of each gene node is determined by logical functions. In this paper, we…

Systems and Control · Electrical Eng. & Systems 2020-11-03 Jie Zhong , Daniel W. C. Ho , Jianquan Lu

We investigated the properties of Boolean networks that follow a given reliable trajectory in state space. A reliable trajectory is defined as a sequence of states which is independent of the order in which the nodes are updated. We…

Biological Physics · Physics 2011-03-23 Tiago P. Peixoto , Barbara Drossel

Boolean Networks (BNs) describe the time evolution of binary states using logic functions on the nodes of a network. They are fundamental models for complex discrete dynamical systems, with applications in various areas of science and…

Discrete Mathematics · Computer Science 2025-03-26 Van-Giang Trinh , Samuel Pastva , Jordan Rozum , Kyu Hyong Park , Réka Albert

Random boolean cellular automata are investigated, where each gate has two randomly chosen inputs and is randomly assigned a boolean function of its inputs. The effect of non-uniform distributions on the choice of the boolean functions is…

adap-org · Physics 2008-02-03 James F. Lynch

We state an algorithm that, given an automata network and a block-sequential update schedule, produces an automata network of the same size or smaller with the same limit dynamics under the parallel update schedule. Then, we focus on the…

Discrete Mathematics · Computer Science 2023-04-27 Pacôme Perrotin , Sylvain Sené

In this paper we try to end the debate concerning the suitability of different updating schemes in random Boolean networks (RBNs). We quantify for the first time loose attractors in asyncrhonous RBNs, which allows us to analyze the…

Adaptation and Self-Organizing Systems · Physics 2011-11-10 Carlos Gershenson

Automata networks are mappings of the form f : Q Z $\rightarrow$ Q Z , where Q is a finite alphabet and Z is a set of entities; they generalise Cellular Automata and Boolean networks. An update schedule dictates when each entity updates its…

Computational Complexity · Computer Science 2020-04-22 Florian Bridoux , Maximilien Gadouleau , Guillaume Theyssier

A Boolean network is a discrete dynamical system operating on vectors of Boolean variables. The action of a Boolean network can be conveniently expressed as a system of Boolean update functions, computing the new values for each component…

Formal Languages and Automata Theory · Computer Science 2023-03-02 Artiom Alhazov , Vincent Ferrari-Dominguez , Rudolf Freund , Nicolas Glade , Sergiu Ivanov

Different Boolean networks may reveal similar dynamics although their definition differs, then preventing their distinction from the observations. This raises the question about the sufficiency of a particular Boolean network for properly…

Discrete Mathematics · Computer Science 2014-11-25 Franck Delaplace

In this paper we study the phase transitions of different types of Random Boolean networks. These differ in their updating scheme: synchronous, semi-synchronous, or asynchronous, and deterministic or non-deterministic. It has been shown…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson

In this paper, we analyse large random Boolean networks in terms of a constraint satisfaction problem. We first develop an algorithmic scheme which allows to prune simple logical cascades and under-determined variables, returning thereby…

Statistical Mechanics · Physics 2009-11-11 L. Correale , M. Leone , A. Pagnani , M. Weigt , R. Zecchina