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Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…

Machine Learning · Computer Science 2025-09-24 Niharika Tewari , Nguyen Linh Dan Le , Mujie Liu , Jing Ren , Ziqi Xu , Tabinda Sarwar , Veeky Baths , Feng Xia

Brain connectivity alternations associated with brain disorders have been widely reported in resting-state functional imaging (rs-fMRI) and diffusion tensor imaging (DTI). While many dual-modal fusion methods based on graph neural networks…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Feiyu Yin , Yu Lei , Siyuan Dai , Wenwen Zeng , Guoqing Wu , Liang Zhan , Jinhua Yu

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Functional magnetic resonance imaging (fMRI) reveals complex brain functional networks with hierarchical topologies crucial for cognitive processing. Standard Euclidean Graph Neural Networks (GNNs) often struggle to represent these…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yunyou Liu , Cheng Yang , Yifei Sun , Feiwei Qin , Changmiao Wang , Yong Peng

Different brain imaging modalities offer unique insights into brain function and structure. Combining them enhances our understanding of neural mechanisms. Prior multimodal studies fusing functional MRI (fMRI) and structural MRI (sMRI) have…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Oktay Agcaoglu , Rogers F. Silva , Deniz Alacam , Sergey Plis , Tulay Adali , Vince Calhoun

We propose a novel approach to Structural Health Monitoring (SHM), aiming at the automatic identification of damage-sensitive features from data acquired through pervasive sensor systems. Damage detection and localization are formulated as…

Machine Learning · Computer Science 2020-02-18 Luca Rosafalco , Andrea Manzoni , Stefano Mariani , Alberto Corigliano

Video-based gait analysis has become a promising approach for assessing motor impairment in children with cerebral palsy (CP). However, existing methods usually rely on either pose sequences or handcrafted gait features alone, making it…

Image and Video Processing · Electrical Eng. & Systems 2026-03-25 Kaiyuan Yang , Xupeng Chen , Jiangpeng He

In MRI-based mental disorder diagnosis, most previous studies focus on functional connectivity network (FCN) derived from functional MRI (fMRI). However, the small size of annotated fMRI datasets restricts its wide application. Meanwhile,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Xingcan Hu , Wei Wang , Li Xiao

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…

Signal Processing · Electrical Eng. & Systems 2024-05-17 Arash Hajisafi , Haowen Lin , Yao-Yi Chiang , Cyrus Shahabi

Suffering from the multi-view data diversity and complexity for semi-supervised classification, most of existing graph convolutional networks focus on the networks architecture construction or the salient graph structure preservation, and…

Machine Learning · Computer Science 2020-06-01 Guangfeng Lin , Jing Wang , Kaiyang Liao , Fan Zhao , Wanjun Chen

Graph neural networks (GNN) rely on graph operations that include neural network training for various graph related tasks. Recently, several attempts have been made to apply the GNNs to functional magnetic resonance image (fMRI) data.…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Byung-Hoon Kim , Jong Chul Ye

Alzheimer's disease (AD) is a neurodegenerative disease known to affect brain functional connectivity (FC). Linear FC measures have been applied to study the differences in AD by splitting neurophysiological signals such as…

Neurons and Cognition · Quantitative Biology 2022-06-14 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

Machine Learning · Statistics 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

Sleep stage classification is essential for sleep assessment and disease diagnosis. Although previous attempts to classify sleep stages have achieved high classification performance, several challenges remain open: 1) How to effectively…

Signal Processing · Electrical Eng. & Systems 2021-09-07 Ziyu Jia , Youfang Lin , Jing Wang , Xiaojun Ning , Yuanlai He , Ronghao Zhou , Yuhan Zhou , Li-wei H. Lehman

Over the past two decades, tools from network science have been leveraged to characterize the organization of both structural and functional networks of the brain. One such measure of network organization is hub node identification. Hubs…

Social and Information Networks · Computer Science 2025-09-05 Meiby Ortiz-Bouza , Duc Vu , Abdullah Karaaslanli , Selin Aviyente

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

Methodology · Statistics 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs cognitive function and quality of life. Timely intervention in AD relies heavily on early and precise diagnosis, which remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xiaoxiao Yang , Meiliang Liu , Yunfang Xu , Zijin Li , Zhengye Si , Xinyue Yang , Zhiwen Zhao