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Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Schizophrenia (SZ) is a complex mental disorder that necessitates accurate and timely diagnosis for effective treatment. Traditional methods for SZ classification often struggle to capture transient EEG features and face high computational…

Signal Processing · Electrical Eng. & Systems 2024-07-26 Umesh Kumar Naik M , Shaik Rafi Ahamed

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

Neurons and Cognition · Quantitative Biology 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

Schizophrenia is a severe yet treatable mental disorder, it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms, therefore there is a need for…

Human-Computer Interaction · Computer Science 2023-10-26 Niki Maria Foteinopoulou , Ioannis Patras

The Disrupted in Schizophrenia Gene 1 (DISC1) plays a role in both neural signalling and development and is associated with schizophrenia, although its links to altered brain structure and function in this disorder are not fully…

Neurons and Cognition · Quantitative Biology 2014-06-10 Xiaohong Gong , Wenlian Lu , Keith M. Kendrick , Weidan Pu , Chu Wang , Li Jin , Guangmin Lu , Zhening Liu , Haihong Liu , Jianfeng Feng

Mental disorders are among the most widespread diseases globally. Analyzing functional brain networks through functional magnetic resonance imaging (fMRI) is crucial for understanding mental disorder behaviors. Although existing fMRI-based…

Neural and Evolutionary Computing · Computer Science 2025-05-26 Jun-En Ding , Dongsheng Luo , Anna Zilverstand , Kaustubh Kulkarni , Feng Liu

Precision psychiatry aspires to elucidate brain-based biomarkers of psychopathology to bolster disease risk assessment and treatment development. To this end, functional magnetic resonance imaging (fMRI) has helped triangulate brain…

Neurons and Cognition · Quantitative Biology 2026-01-23 Cole Korponay

Despite the promising performance of state of the art approaches for Parkinsons Disease (PD) detection, these approaches often analyze individual speech segments in isolation, which can lead to suboptimal results. Dysarthric cues that…

Machine Learning · Computer Science 2024-09-17 Shakeel A. Sheikh , Yacouba Kaloga , Md Sahidullah , Ina Kodrasi

Recently, there has been a growing interest in monitoring brain activity for individual recognition system. So far these works are mainly focussing on single channel data or fragment data collected by some advanced brain monitoring…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Lei Chu , Robert Qiu , Haichun Liu , Zenan Ling , Tianhong Zhang , Jijun Wang

Brain function and connectivity is a pressing mystery in medicine related to many diseases. Neural connectomes have been studied as graphs with graph theory methods including topological methods. Work has started on hypergraph models and…

Methodology · Statistics 2022-05-09 Michael G. Rawson

This paper introduces a novel Functional Graph Convolutional Network (funGCN) framework that combines Functional Data Analysis and Graph Convolutional Networks to address the complexities of multi-task and multi-modal learning in digital…

Machine Learning · Computer Science 2024-09-11 Tobia Boschi , Francesca Bonin , Rodrigo Ordonez-Hurtado , Cécile Rousseau , Alessandra Pascale , John Dinsmore

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

Machine Learning · Computer Science 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

Signal Processing · Electrical Eng. & Systems 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…

Brain imaging of mental health, neurodevelopmental and learning disorders has coupled with machine learning to identify patients based only on their brain activation, and ultimately identify features that generalize from smaller samples of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Laura Tomaz Da Silva , Nathalia Bianchini Esper , Duncan D. Ruiz , Felipe Meneguzzi , Augusto Buchweitz

Coronary heart disease (CHD) arises from complex interactions among uncontrollable factors, controllable lifestyle factors, and clinical indicators, where relationships are often uncertain. Fuzzy subgraph connectivity (FSC) provides a…

Artificial Intelligence · Computer Science 2025-09-23 Shanookha Ali , Nitha Niralda P C

There are two fundamental problems in applying deep learning/machine learning methods to disease classification tasks, one is the insufficient number and poor quality of training samples; another one is how to effectively fuse multiple…

Machine Learning · Computer Science 2023-07-25 Menglin Kong , Shaojie Zhao , Juan Cheng , Xingquan Li , Ri Su , Muzhou Hou , Cong Cao

Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene expression are likely to underpin much of human diversity,…

Genomics · Quantitative Biology 2019-05-31 Akram Yazdani , Raul Mendez Giraldez , Ahmad Samiei