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Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

With the advent of large language models (LLMs), there is a growing interest in applying LLMs to scientific tasks. In this work, we conduct an experimental study to explore applicability of LLMs for configuring, annotating, translating,…

Human-Computer Interaction · Computer Science 2025-10-13 Orcun Yildiz , Tom Peterka

Large language models (LLMs) have emerged as powerful tools with transformative potential across numerous domains, including healthcare and medicine. In the medical domain, LLMs hold promise for tasks ranging from clinical decision support…

Computation and Language · Computer Science 2024-05-14 Xiaolan Chen , Jiayang Xiang , Shanfu Lu , Yexin Liu , Mingguang He , Danli Shi

Large language models (LLMs) excel at modeling relationships between strings in natural language and have shown promise in extending to other symbolic domains like coding or mathematics. However, the extent to which they implicitly model…

Computation and Language · Computer Science 2025-07-18 Andrew Shin , Kunitake Kaneko

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language Models (LLMs) have great potential in the field of health care, yet they face great challenges in adapting to rapidly evolving medical knowledge. This can lead to outdated or contradictory treatment suggestions. This study…

Computation and Language · Computer Science 2025-09-09 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Lucas A. Salas , Jiang Gui

Several recent works seek to adapt general-purpose large language models (LLMs) and vision-language models (VLMs) for medical applications through continued pretraining on publicly available biomedical corpora. These works typically claim…

Computation and Language · Computer Science 2025-07-01 Daniel P. Jeong , Pranav Mani , Saurabh Garg , Zachary C. Lipton , Michael Oberst

This study presents a systematic approach to identifying and characterizing student misconceptions in online learning environments through a novel combination of quantitative performance analysis and large language model (LLM) assessment.…

Computation and Language · Computer Science 2026-05-04 Michael J. Parker , Maria G. Zavala-Cerna

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…

Artificial Intelligence · Computer Science 2025-08-27 Armin Berger , Sarthak Khanna , David Berghaus , Rafet Sifa

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Data plays a fundamental role in training Large Language Models (LLMs). Efficient data management, particularly in formulating a well-suited training dataset, is significant for enhancing model performance and improving training efficiency…

Computation and Language · Computer Science 2024-08-05 Zige Wang , Wanjun Zhong , Yufei Wang , Qi Zhu , Fei Mi , Baojun Wang , Lifeng Shang , Xin Jiang , Qun Liu

Large Language Models (LLMs) have demonstrated significant potential in medicine, with many studies adapting them through continued pre-training or fine-tuning on medical data to enhance domain-specific accuracy and safety. However, a key…

Large language models (LLMs) have been widely adopted in various downstream task domains. However, their abilities to directly recall and apply factual medical knowledge remains under-explored. Most existing medical QA benchmarks assess…

Computation and Language · Computer Science 2025-08-20 Jiaxi Li , Yiwei Wang , Kai Zhang , Yujun Cai , Bryan Hooi , Nanyun Peng , Kai-Wei Chang , Jin Lu

The growing capabilities of Large Language Models (LLMs) show significant potential to enhance healthcare by assisting medical researchers and physicians. However, their reliance on static training data is a major risk when medical…

Computation and Language · Computer Science 2025-09-05 Juraj Vladika , Mahdi Dhaini , Florian Matthes

This paper presents a comprehensive evaluation of the capabilities of Large Language Models (LLMs) in metaphor interpretation across multiple datasets, tasks, and prompt configurations. Although metaphor processing has gained significant…

Computation and Language · Computer Science 2025-07-22 Elisa Sanchez-Bayona , Rodrigo Agerri

In the age of Large Language Models (LLMs), much work has already been done on how LLMs support medication advice and serve as information providers; however, how mothers use these tools for emotional and informational support to avoid…

Human-Computer Interaction · Computer Science 2026-03-10 Shayla Sharmin , Sadia Afrin Ratna

Knowledge sharing is crucial in healthcare, especially when leveraging data from multiple clinical sites to address data scarcity, reduce costs, and enable timely interventions. Transfer learning can facilitate cross-site knowledge…

Computation and Language · Computer Science 2024-09-24 Yuhe Gao , Runxue Bao , Yuelyu Ji , Yiming Sun , Chenxi Song , Jeffrey P. Ferraro , Ye Ye